Optimization of Headspace Solid Phase Microextraction Procedure for Trace Analysis of Toluene

• Autorzy: Heidari H. R. , Shahtaheri S. J. , Golbabaei F. , Alimohammadi M. , Rahimi-Froushani A.
• Języki publikacji: EN

Abstrakty

EN

This study describes optimization of headspace solid phase microextraction followed by gas chromatography equipped with a flame ionization detector for toluene at trace level in spiked urine. The parameters affecting the extraction and gas chromatographic determination of analytes were studied: extraction time and temperature; desorption time and temperature; addition of NaCl; and pH, volume and agitation of the sample. Optimized headspace extraction was carried out at 30 °C for 6 min in the presence of 0.2 g⋅m–1of NaCl in the sample solution. Also, sample volume and sample pH were optimized at 5 ml and 7 (neutral pH), respectively. Desorption of the analytes was carried out at 250 °C for 60 s. The optimized procedure was validated with 3 different pools of spiked urine; it showed good reproducibility over 6 consecutive days and 6 within-day experiments. The study also determined the accuracy, linearity and detection limits of this method.

Słowa kluczowe

EN

headspace; solid phase microextraction; gas chromatography; toluene

• Wydawca: Taylor & Francis
• Czasopismo: International Journal of Occupational Safety and Ergonomics
• Rocznik: 2008
• Tom: Vol. 14, No. 4
• Strony: 395--405
• Opis fizyczny: Bibliogr. 23 poz., tab., wykr.

Twórcy

autor

Heidari H. R.

• School of Public Health & Institute of Public Health Research, Tehran University of Medical Sciences, I.R. Iran

autor

Shahtaheri S. J.

• School of Public Health & Institute of Public Health Research, Tehran University of Medical Sciences, I.R. Iran

autor

Golbabaei F.

• School of Public Health & Institute of Public Health Research, Tehran University of Medical Sciences, I.R. Iran

autor

Alimohammadi M.

• School of Public Health & Institute of Public Health Research, Tehran University of Medical Sciences, I.R. Iran

autor

Rahimi-Froushani A.

• School of Public Health & Institute of Public Health Research, Tehran University of Medical Sciences, I.R. Iran

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