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Effects of flattening filter (FF) and flattening filter-free (FFF) beams on small-field and large-field dose distribution using the VMAT treatment plan

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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Introduction: The aim of the study was to evaluate the influence of flattening filter (FF) and flattening filter-free (FFF) beams on small-field and large-field dose distribution using the VMAT treatment plan. Material and methods: Dose distribution calculations were performed for the VMAT technique in two locations: the larynx (small irradiation field; average 30.1 cm2) and gynecology (large irradiation field; average 173.1 cm2) using X- 6MV flattening filter (FF) and flattening filter-free (FFF) beams. The following values were compared: the number of monitor units, minimum doses, average doses in PTV and maximum average doses in OaR (spinal cord – in larynx radiotherapy, bladder and rectum - in gynecological radiotherapy) and RPI (Radiation Planning Index) coefficient. Results and Discussion: The performed statistical tests indicate that there is a significant difference (p <0.05) between the number of monitor units in the irradiation of large (gynecological) fields between the FF and FFF beams. The dose distributions show no statistically significant differences between the flattening filter and flattening-free filter beams (regardless of the field size). Conclusions: Due to the smaller number of monitor units, it is recommended to use flattening filter beams (FF) for largefield radiotherapy.
Rocznik
Strony
137--141
Opis fizyczny
Bibliogr. 21 poz., rys., tab.
Twórcy
  • Maria Skłodowska - Curie National Research Institute of Oncology, Gliwice Branch, Poland; Radiotherapy Planning Department
  • Maria Skłodowska - Curie National Research Institute of Oncology, Gliwice Branch, Poland; Radiotherapy Planning Department
  • Maria Skłodowska - Curie National Research Institute of Oncology, Gliwice Branch, Poland; Radiotherapy Planning Department
Bibliografia
  • 1. Ślosarek K. Podstawy planowania leczenia w radioterapii. Gliwice: Polskie Towarzystwo Onkologiczne, Oddział Śląski; 2007.
  • 2. Malicki J, Ślosarek K. Planowanie leczenia i dozymetria w radioterapii. Gdańsk: VIA MEDICA; 2016.
  • 3. Waligórski M, Lesiak J. Podstawy Radioterapii. Warszawa: PWN; 2000.
  • 4. Łobodziec W. Dozymetria promieniowania jonizującego w radioterapii. Katowice: Wyd. UŚ; 1999.
  • 5. Kukołowicz P. Charakterystyka wiązek terapeutycznych fotonów i elektronów. Kielce: RTA; 2001.
  • 6. Van Dam J, Marinello G. Methods for in vivo dosimetry in external radiotherapy. Brussels: ESTRO; 1994.
  • 7. Jia F, Xu D, Yue H, Wu H, Li G. Comparison of Flattening Filter and Flattening Filter-Free Volumetric Modulated Arc Radiotherapy in Patients with Locally Advanced Nasopharyngeal Carcinoma. Med Sci Monit. 2018;24:8500-8505. https://doi.org/10.12659/MSM.910218
  • 8. Ma C, Chen M, Long T, Parsons D, et al. Flattening filter free in intensity modulated radiotherapy (IMRT) - Theoretical modeling with delivery efficiency analysis. Med Phys. 2019;46(1):34-44. https://doi.org/10.1002/mp.13267
  • 9. Alvarez Moret J, Obermeier T, Pohl F. Second cancer risk after radiation therapy of ependymoma using the flattening filter free irradiation mode of a linear accelerator. J Appl Clin Med Phys. 2018;19(5):632-639. https://doi.org/10.1002/acm2.12438
  • 10. Wang L, Ding G. Estimating the uncertainty of calculated out-of-field organ dose from a commercial treatment planning system. J Appl Clin Med Phys. 2018;19(4):319-324. https://doi.org/10.1002/acm2.12367
  • 11. Yao C, Chang T, Lin C. Three-dimensional dose comparison of flattening filter (FF) and flattening filter-free (FFF) radiation therapy by using NIPAM gel dosimetry. PLoSOne. 2019;14(2):e0212546. https://doi.org/10.1371/journal.pone.0212546
  • 12. Irazola L, Sánchez-Nieto B, García-Hernández M. 10-Mv SBRT FFF Irradiation Technique is associated to the lowest peripheral dose: the outcome of 142 treatment plans for the 10 most common tumor locations. Radiat Prot Dosimetry. 2019;185(2):183-195. https://doi.org/10.1093/rpd/ncy292
  • 13. Aoki S, Yamashita H, Haga A. Flattening filter-free technique in volumetric modulated arc therapy for lung stereotactic body radiotherapy: A clinical comparison with the flattening filter technique. Oncol Lett. 2018;15(3):3928-3936. https://doi.org/10.3892/ol.2018.7809
  • 14. Duane S. Dosimetry for Flattening Filter Free (FFF) linac beams and small fields (SF). National Physics Laboratory, 2013.
  • 15. Dobler B, Obermeier T, Hautmann M. Simultaneous integrated boost therapy of carcinoma of the hypopharynx/larynx with and without flattening filter - a treatment planning and dosimetry study. Radiat Oncol. 2017;12(1):114. https://doi.org/10.1186/s13014-017-0850-8
  • 16. Maier J, Knott B, Maerz M. Simultaneous integrated boost (SIB) radiation therapy of right sided breast cancer with and without flattening filter - A treatment planning study. Radiat Oncol. 2016;11(1):111. https://doi.org/10.1186/s13014-016-0687-6
  • 17. Dobler B, Maier J, Knott B. Second Cancer Risk after simultaneous integrated boost radiation therapy of right sided breast cancer with and without flattening filter. Strahlenther Onkol. 2016;192(10):687-95. https://doi.org/10.1007/s00066-016-1025-5
  • 18. Baic B, Kozłowska B, Kwiatkowski R, Dybek M. Clinical advantages of using unfl attened 6-MV and 10-MV photon beams generated by the medical accelerator Elekta Versa HD based on their dosimetric parameters in comparison to conventional beams. Nukleonika;2019:64(3):77-86. https://doi.org/10.2478/nuka-2019-0010
  • 19. Ślosarek K, Grządziel A, Szlag M, Bystrzycka J. Radiation Planning Index for dose distribution evaluation in stereotactic radiotherapy. Reports of Practical Oncology and Radiotherapy. 2008;13(4):182-186. https://doi.org/10.1016/S1507-1367(10)60007-7
  • 20. Leszczyński W, Ślosarek K, Szlag M. Comparison of dose distribution in IMRT and RapidArc technique in prostate radiotherapy.Reports of Practical Oncology and Radiotherapy, 2012;17(6):348-351. https://doi.org/10.1016/j.rpor.2012.05.002
  • 21. Radwan M, Grządziel A, Hawrylewicz L, Ślosarek K, Osewski W. The influence of photon energy on dose distribution for IMRT and VMAT plans. Nowotwory Journal of Oncology. 2014;64(3):230-236. https://doi.org/10.5603/NJO.2014.0037
Uwagi
Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2021).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-df533b64-8a2d-4b0f-85ab-0ff484fa5b99
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