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The irritation potencies of 8 dental polymer products, used as dental restorative materials, adhesives, or temporary constructions, were tested using the HET-CAM (hen's egg test-chorioallantoic membrane) technique. Liquid and powder components, and extracts of cured and freshly mixed non-cured materials of 5 glass ionomers, 1 bonding, 1 composite, and 1 cold-cured acrylate were examined. Results showed that the liquid component of all products had a strong irritation capacity but powder suspensions and extracts from cured and freshly mixed non-cured materials had no effect on the CAM. Thus, dental personnel who handle liquid and powder manually are exposed to components with a high irritation potential, in contrast to patients who are exposed to the cured and mixed non-cured materials with low irritation potential. This illustrates the importance of safe handling procedures and practices for dental personnel who handle non-cured polymers manually.
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Tom
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43--57
Opis fizyczny
Bibliogr. 43 poz., tab.
Twórcy
autor
- Lulea University of Technology, Sweden
- NIOM - Scandinavian Institute of Dental Materials, Norway
autor
- NIOM - Scandinavian Institute of Dental Materials, Norway
autor
- Lulea University of Technology, Sweden
Bibliografia
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- [3] Dahl, J. (1999). Irritation of dental adhesive agents evaluated by the HET-CAM test. Toxicology in Vitro, 13, 259-264.
- [4] de Silva, O., Cottin, M., Dami, N., Roguet, R., Catroux, P., Toufic, A., Sicard, C., Dossou, K.G., Gerner. I., Schlede. E., Spielmann. H., Gupta, K.C., & Hills, R .N. (1997). Evaluation of eye irritation potential: Statistical analysis and tier strategies. Food and Chemical Toxicology, 55(1), 159-164.
- [5] Feder, P., Carr, G., Holzhutter, H.G., Lowell, D., & Springer, J. (1997). Statistical planning and analysis considerations in the evaluation of in vitro alternatives to whole animal use for eye irritation testing. Food and Chemical Toxicology, 55(1),167-174.
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- [7] Halker-Sørensen, L. (1998). Occupational skin diseases: Reliability and utility of the data in the various registers; the course from notification to compensation and the costs. Contact Dermatitis, 39, 71-78.
- [8] Hensten-Pettersen, A. (1998). Skin and mucosal reactions associated with dental materials. European Journal of Oral Sciences, 106, 707-712.
- [9] Hensten-Pettersen, A., & Jacobsen, N. (1991). Perceived side effects of biomaterials in prosthetic dentistry. Journal of Prosthetic Dentistry, (55(1), 138-144.
- [10] Hill, J.G., Grimwood, R.E., Hermesch, C.B., & Marks, J.G., Jr. (1998). Prevalence of occupational related hand dermatitis in dental workers. Journal of American Dental Association, 129(2), 212-217.
- [11] International Organization for Standardization (ISO). (1996). Biological evaluation of medical devices-part 12: Sample preparation and reference materials. (Standard No. ISO 10993-12:1996). Geneva, Switzerland: Author.
- [12] Jacobsen, N., Aasenden, R., & Hensten-Pettersen, A. (1991). Occupational health complaints and adverse patient reactions as perceived by personnel in public dentistry. Community Dental Oral Epiodemiology, 19(3), 155-159.
- [13] Jacobsen, N., Derand, T., & Hensten-Pettersen, A. (1996). Profile of work-related health complaints among Swedish dental laboratory technicians. Community Dental Oral Epidemiology, 24, 138-144.
- [14] Jacobsen, N., & Hensten-Pettersen, A. (1993). Self-reported occupation-related health complaints among dental laboratory technicians. Quintessence International, 24(6), 409-415.
- [15] Jacobsen, N., & Hensten-Pettersen, A. (1995). Occupational health problems among dental hygienists. Community Dental Oral Epiodemiology, 23, 177-181.
- [16] Jolanki, R., Kanerva, L., & Estlander, T. (1995). Occupational allergic contact dermatitis caused by epoxy diacrylate in ultraviolet-light-cured paint, and bisphenol A in dental composite resin. Contact Dermatitis, 33(2), 94-99.
- [17] Jolanki, R., Kanerva, L., & Estlander, T. (1996). Allergic patch test reaction to diglycidyl ether of bisphenol A in hardened nail base and top coat. Contact Dermatitis, ,?5(4), 246-247.
- [18] Kalweit, S., Besoke, R., Gerner, I., & Spielmann, H. (1990). A national validation project of alternative methods to the Draize rabbit eye test. Toxicology in Vitro, 4(5), 702-706.
- [19] Kanerva, L., Estlander, T., & Jolanki, R. (1994). Occupational skin allergy in the dental profession. (1994). Clinical Dermatology, 12(3), 517-532.
- [20] Kanerva, L., Estlander, T., & Jolanki, R. (1997). Occupational allergic contact dermatitis caused by acrylic tri-cure glass ionomer. Contact Dermatitis, 37(1), 49-50.
- [21] Kanerva, L., Estlander, T., Jolanki, R., & Tarvainen, K. (1993). Occupational allergic contact dermatitis caused by exposure to acrylates during work with dental prostheses. Contact Dermatitis, 28(5), 168-175.
- [22] Kanerva, L., Henriks-Eckerman, M.L., Jolanki, R., & Estlander, T. (1997). Plastics acrylics: Material safety data sheets need to be improved. Clinical Dermatology, 15(A), 533-546.
- [23] Kanerva, L., Jolanki, R., & Estlander, T. (1997). 10 years of patch testing with the (metha)acrylate series. Contact Dermatitis, 37(6), 255-258.
- [24] Kanerva, L., Mikola, H ., Henriks-Eckerm an, M.L., Jolanki, R., & Estlander, T. (1998). Fingertip paresthesia and occupational allergic contact dermatitis caused by acrylics in a dental nurse. Contact Dermatitis, 38(2), 114-116.
- [25] Kieć-Świerczyńska, M.K. (1996). Occupational allergic contact dermatitis due to acrylates in Lódź. Contact Dermatitis, 34(6), 419-422.
- [26] Lönnroth, E-C., & Shahnavaz, H . (1998a). Adverse health reactions in skin, eyes, and respiratory tract among dental personnel in Sweden. Swedish Dental Journal, 22, 33-45.
- [27] Lönnroth, E-C., & Shahnavaz, H. (1998b). Hand dermatitis and symptoms from the fingers among Swedish Dental Personnel. Swedish Dental Journal, 22, 23-32.
- [28] Lönnroth, E-C., & Shahnavaz, H. (1998c). The correlation between symptoms, frequent use of dental polymers, and evaluation of health risk. International Journal of Occupational Safety and Ergonomics, 4(A), 411-423.
- [29] Munksgaard, E.C. (1992). Permeability of protective gloves to (di)methacrylates in resinous dental materials. Scandinavian Journal of Dental Research, 100, 182-192.
- [30] Munksgaard, E.C., Hansen, E.K., Engen, T., & Holm, U. (1996). Self-reported occupational dermatological reactions among Danish dentists. European Journal of Oral Sciences, 104(4), 396-402.
- [31] Mystkowska-Bączkowska, E.T., Komar, A., Samos-Zielińiska, J., Stroińiska, W., & Rogulska, T. (1995). Ocena przydatności błony omoczniowo-kosmówkowej zarodka kury do testowania drażniących właściwości substancji chemicznych [Evaluation of the chorioallantoic membrane in the chick embryo to test the irritation potential of chemical and cosmetic products], Roczniki Państwowego Zakładu Higieny, 46(A), 407-415.
- [32] Rustemeyer, T., & Frosh, P.J. (1994). Contact allergies in medical occupation. Hautartz, 45 (12), 838-844.
- [33] Rustemeyer, T., & Frosh, P.J. (1996). Occupational skin diseases in dental laboratory technicians. (1) Clinical picture and causative factors. Contact Dermatitis, 34, 15-33.
- [34] Savonius, B., Keskinen, H., Tupparainen, M., & Kanerva, L. (1993). Occupational respiratory disease caused by acrylates. Clinical and Experimental Allergy, 23, 416-424.
- [35] Schendel, K .U., Erdinger, L., Komposch, G., & Sonntag, H.-G . (1994). Untersuchung kierferorthopädisher materialen in HET-CAM-test auf schleimhautreizende Wirkung [Studying the skin irritation effects of dental orthopaedic materials with the HET-CAM technique]. Fortschritte der Kieferorthopädie, 55, 28-35.
- [36] Schendel, K.U., Erdinger, L., Komposch, G., & Sonntag, H.-G. (1995). Neonfarbene Kunststoffe für kierferorthopädishe Apparaten [Plastic neon colours in dental orthodontic devices]. Fortschritte der Kieferorthopädie, 56, 4-48.
- [37] Socialstyrelsen (SOSFS). (1994). Medidnsktekniska produkter [Medical technical products] (The statue book of the Swedish National Board of Health and Safety No.1994: 20). Stockholm: Author.
- [38] Spielmann, H. (1992). The Ergatt/Frame data bank of in vitro techniques in toxicology. HET-CAM test (Protocol No. 47). Available E-mail: <invittox@frame-uk.demon.co.uk>.
- [39] Spielmann, H., Kalweit, S., Liebsch, M., Wirnsberger, T., Gerner, I., Bertram-Neis, E., Krauser, K., Kreiling, R., Miltenburger, H G., Pape, W., & Steiling, W. (1993). Validation study of alternatives to the Draize eye irritation test in Germany; Cytotoxicity testing and HET-CAM-test with 136 industrial chemicals. Toxicology in Vitro, 7, 505-510.
- [40] Spielmann, H., Liebsch, M., Moldenhauer, F., Holzhutter, H .G., Bagley, D .M., Lipman, J.M., Pape, W.J., Miltenburger, H., de Silva, O., Hofer, H., & Steiling, W. (1997). IRAG working group 2. CAM -based assays. Interagency Regulatory Alternatives Group. Food and Chemical Toxicology, 35(1), 39-66.
- [41] Stingeni, L., Lapomarda, V., & Lisi, P. (1995). Occupational hand dermatitis in hospital environments. Contact Dermatitis, 33(3), 172-176.
- [42] Uveges, R.E., Grimwood, R.E., Slawsky, L.D., & Marks, J.G., Jr. (1995). Epidemiology of hand dermatitis in dental personnel. Military Medicine, 169(1), 335-338.
- [43] Wiegleb, K., Lange, N., & Kuhnert, M. (1993). The use of HET-CAM test for the determination of the irritating effects of humic acid. Deutche Tierarztliche Wochenschrift, 700(10), 412-416.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-df2a8982-e438-4249-a30d-4191eb61f4c8