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Study on in vitro toxicity of biometal(II) Monensinates against rat Zajdela liver tumour

Treść / Zawartość
Identyfikatory
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The ability of Monensic acid A (MonH∙H2O) and its neutral metal complexes [M(Mon)2(H2O)2]with ions of Mg2+, Ca2+, Mn2+, Co2+, Ni2+ and Zn2+ to decrease viability and proliferation of primary cell cultures, originating from a chemically induced transplantable liver tumour of Zajdela in rats, and bone marrow cells from the same tumour-bearers, was evaluated. Experimental data revealed that manganese(II) and nickel(II) complexes of Monensin A are relatively more selective against the tumour as compared to the healthy bone marrow cells.
Rocznik
Strony
125--132
Opis fizyczny
Bibliogr. 45 poz., rys., wykr.
Twórcy
  • Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. G. Bonchev 25, 1113 Sofia, Bulgaria
  • Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. G. Bonchev 25, 1113 Sofia, Bulgaria
  • Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. G. Bonchev 25, 1113 Sofia, Bulgaria
  • Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. G. Bonchev 25, 1113 Sofia, Bulgaria
autor
  • Institute of Neurobiology, Bulgarian Academy of Sciences, Acad. G. Bonchev 23, 1113 Sofia, Bulgaria
  • Department of Analytical Chemistry, Faculty of Chemistry and Pharmacy, Sofia University “St. Kliment Ohridski”, J. Bourchier Blvd. 1, 1164 Sofia, Bulgaria
autor
  • Biovet Ltd., Research and Development Department, 4550 Peshtera, Bulgaria
Bibliografia
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Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-de0f2e56-2e3a-4176-a954-c7504d839732
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