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Abstrakty
Four alkannins, isobutylalkannin (1), β,β-dimethylacrylalkannin (2), acetylalkannin (3) and β-hydroxyisovalerylalkannin (4), two shikonofurans: shikonofuran C (5), shikonofuran D (6), and a number of sterols as well as esterified acids, have been isolated and determined from the n-hexane extract of Lithospermum canescens transgenic roots. Pigments 1 and 4 are reported in the present work as novel metabolites within Lithospermum genus, while it is also the first detailed chemical analysis of transgenic roots from the studied species. All chemical structures were determined by modern chromatographic and spectral means as GC-MS, ESI-MS, and NMR.
Słowa kluczowe
Czasopismo
Rocznik
Tom
Strony
353--363
Opis fizyczny
Bibliogr. 21 poz., rys., tab.
Twórcy
autor
- University of Athens Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy Zografou Campus 15771 Athens Greece
autor
- Medical University of Warsaw Department of Biology and Pharmaceutical Botany, Faculty of Pharmacy Banacha str. 1 02-097 Warsaw Poland
autor
- Medical University of Warsaw Department of Biology and Pharmaceutical Botany, Faculty of Pharmacy Banacha str. 1 02-097 Warsaw Poland
autor
- University of Athens Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy Zografou Campus 15771 Athens Greece
autor
- Medical University of Warsaw Department of Biology and Pharmaceutical Botany, Faculty of Pharmacy Banacha str. 1 02-097 Warsaw Poland
autor
- University of Athens Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy Zografou Campus 15771 Athens Greece
Bibliografia
- [1] V.P. Papageorgiou, A.N. Assimopoulou, E.A. Couladouros, D. Hepworth, and K.C. Nicolaou. Angew. Chem. Int. Ed., 38, 270 (1999)
- [2] A. Pietrosiuk, M. Furmanowa, E. Skopińska-Różewska, E. Sommer, et al. Acta Pol. Pharm. — Drug Res., 61, 379 (2004)
- [3] Pietrosiuk, E. Skopińska-Różewska, M. Furmanowa, H. Wiedenfeld, et al. Pharmazie, 59, 640 (2004)
- [4] Pietrosiuk and H. Wiedenfeld. Pharm. Biol., 43, 189 (2005)
- [5] H. Wiedenfeld, A. Pietrosiuk, M. Furmanowa, and E. Roeder. Z. Naturforsch., 58c, 173 (2003)
- [6] A. Pietrosiuk, K. Sykłowska-Baranek, H. Wiedenfeld, R. Wolanowska, et al. Plant Cell Rep., 25, 1052 (2006)
- [7] E.F. Linsmaier and F. Skoog. Physiol. Plant, 18, 100 (1965)
- [8] Y. Fujita, Y. Hara, C. Suga, and T. Morimoto. Plant Cell Rep., 1, 61 (1981)
- [9] K. Shimomura, H. Sudo, H. Sada, and H. Kamada. Plant Cell Rep., 10, 282 (1991)
- [10] H.N. Chang, and S.J. Sim, in: Y.P.S. Bajaj (ed), Biotechnology in Agriculture and Forestry, vol. 38. Plant Protoplasts and Genetic Engineering VII, Springer-Verlag, Berlin-Heidelberg, 1996, pp. 233–242
- [11] K. Yazaki, S. Tanaka, H. Matsuoka, and F. Sato. Plant Cell Rep., 18, 214 (1998)
- [12] M.H. Cho, Y.S. Paik, and T.R. Hahn. Arch. Pharm. Res., 22, 414 (1999)
- [13] N. Kirimer, B. Bozan, and K.H.C. Başer. Fitoterapia, 66, 499 (1995)
- [14] J.S. Kang, B.Z. Ahn, and G. Blaschke. Arch. Pharm. Res., 21, 565 (1998)
- [15] F. Shanlin, S. Tianmin, and X. Peigen. Yaoxue Xuebao, 19, 921 (1984)
- [16] Y. Hu, Z. Jiang, K.S.Y. Leung, and Z. Zhao. Anal. Chim. Acta, 577, 26 (2006)
- [17] X.C. Weng, G.Q. Xiang, A.L. Jiang, Y.P. Liu, et al. Food Chem., 69, 143 (2000)
- [18] Morimoto and Y. Hirata. Tetrahedron Lett., 7, 3677 (1966)
- [19] M.H. Cho, Y.S. Paik, and T.R. Hahn. J. Agric. Food Chem., 47, 4117 (1999)
- [20] J. Han, X. Weng, and K. Bi. Food Chem., 106, 2 (2008)
- [21] F. Yoshizahi, S. Hismichi, Y. Kondo, Y. Sato, and S. Nozol. Chem. Pharm. Bull., 30, 4407
Typ dokumentu
Bibliografia
Identyfikator YADDA
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