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Synthesis, Spectral Studies and Biological Screening of 2-(4'-chlorophenyl)-6-methyl-(3-N, n’-Diaryl/Dialkyl Amino methyl)-imidazo[1,2-a]pyridine

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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
2-(4'-chlorophenyl)-6-methyl- (3-N, N'- diaryl/dialkyl amino methyl)-imidazo [1, 2-a] pyridine (4a-4l) has been synthesized. The products have been assayed for their biological activity against Gram +ve, Gram –ve bacteria and fungi. Some of the products showed moderate activity in concentration 50μg/ml. The structures of the products have been elucidated by IR, 1H-NMR, Mass spectral data, elemental analysis and thin layer chromatography.
Rocznik
Tom
Strony
167--171
Opis fizyczny
Bibliogr. 15 poz., rys., tab., wz.
Twórcy
autor
  • Shree M. & N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India
  • Shree M. & N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India
  • Shree M. & N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India
  • Shree M. & N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India
Bibliografia
  • [1]. D. B. Shinde, M. S. Shingare; Indian J. Chem., 30B, 450, 1991.
  • [2]. G. A. Kileigil and R. Ertan; J. Heterocycl. Chem., 35, 1485, 1998.
  • [3]. Saheyla Ozbey and Engin Kendi; J. Heterocycl. Chem., 35, 1485, 1998.
  • [4]. N. Latif, N. Mishrky and N. S. Girgis; Indian J. Chem., 20B, 147-149, 1981.
  • [5] W. von Behenburg, J. Engel, J. Heese and K. Thiele; Ger. Often., D.E., 3, 337, 593 (Cl C07D 213/72), 1984; Chem. Abstr., 101, 130595n, 1984.
  • [6] L. Castedo, J. M. Quintela and R. Riguers; Eur. J. Med. Chem. Chim. Ther., 19(6), 555, 1984 Chem. Abstr., 103, 37337, 1985.
  • [7] M. R. Pavia, C. P. Taylor, F. M. Hershenson and S. J. Lobbestael; J. Med. Chem., 30, 1210, 1987.
  • [8] W. L. Hoefling, D. Elhaner and E. Reckling; VEB Leund-Werke “Walter Ulbricht” Ger., 1,193, 506, 1965; Chem. Abstr., 63, 6979, 1965.
  • [9] Thiele Kurt, Von Be Benburg and E. Walter; S. African 6, 905, 06, 13 Feb., 1970.
  • [10] Rae Ducan Robertson and Gibson Samuel George; PCT Int. Appl. Wo, 98, 21, 206, EP Appl. 96/203,175 , 1996 ; Chem.Abstr.,129,27899u, 1998.
  • [11] J. Knoll; Naunyn-Schmiedebergs Arch. Exp. Pathol. Pharmakol., 236, 92,1959.
  • [12] J. Knoll; Naunyn-Schmiedebergs Arch. Exp. Pathol. Pharmakol., 238, 114, 1960.
  • [13] V. J. Ram and N. Haque; Indian J. Chem., 34, 514, 1995.
  • [14] L. H. Schmidt and Ruth Crosby; Antimicrobial agents and Chemotherapy, 15(5), 672-679, 1978.
  • [15] A. L. Barry; the antimicrobial acceptability test, principal and practices, edited by illus Lee and febiger; 180, Bio. Abstr., 64, 25183,1997.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-d9a1fca9-8c52-45dd-b964-980ffaee3083
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