Two Step One-Pot Synthesis of Novel 5-(4-Fluorophenyl)-1H-Beno[e][1,4]Diazepin-2(3H)-One and it’s Base Catalyzed Transformation to N-Alkyl and C-3 Arylidene Derivatives

• Autorzy: Patel Anil S. , Khunt H. R. , Ghelani S. M. , Babariya J. S. , Vilapara K. V. , Naliapara Y. T.
• Języki publikacji: EN

Abstrakty

EN

We have demonstrated two step one-pot synthesis of novel 5-(4-Fluorophenyl)-1H-Beno[e][1,4]Diazepin-2(3H)-one using 2-Amino-4’-fluorobenzophenone as initial stating material. The small library of N-alkylation and C-3 benzylidene derivatives have been synthesized by base catalyzedreaction of 5-(4-fluorophenyl)-1H-benzo[e][1,4]diazepin-2(3H)-one (3) nucleus with various alkyl halides and aromatic aldehydes respectively.

Słowa kluczowe

EN

benzodiazepines; base catalyzed; cross-aldol

• Wydawca: Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"
• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2014
• Tom: Vol. 11, iss. 2
• Strony: 106--115
• Opis fizyczny: Bibliogr. 18 poz., tab., wz.

Twórcy

autor

Patel Anil S.

• Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

autor

Khunt H. R.

• Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

autor

Ghelani S. M.

• Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

autor

Babariya J. S.

• Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

autor

Vilapara K. V.

• Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

autor

Naliapara Y. T.

• Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

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