Powiadomienia systemowe
- Sesja wygasła!
- Sesja wygasła!
Tytuł artykułu
Treść / Zawartość
Pełne teksty:
Identyfikatory
Warianty tytułu
Hydrogel patches soothing migraine symptoms
Języki publikacji
Abstrakty
Migraine is a chronic neurological disorder that directly affects up to one billion people worldwide. Current treatments for migraine involve acute treatment, including the use of analgesics, nonsteroidal anti-inflammatory drugs, triptans, and preventive treatment. One of the currently available solution relieving migraine symptoms is hydrogel patches. They typically provide a cooling effect due to the presence of an active substance, most commonly menthol. Unfortunately, despite menthol's undeniable advantages in cooling applications, its intense smell may be irritating for people with migraines, who suffer from olfactory hypersensitivity. Therefore, the following work proposes a novel solution that combines the benefits of hydrogels with a natural extract of feverfew, which is described in the literature as effective in relieving headaches, including migraines. In this study, hydrogel patches were developed based on a natural polymer and modified with feverfew extract. The physicochemical properties of the resulting materials were investigated, including swelling behavior, surface wettability, and substance release from the polymer matrix. The potential for use in the intended application was preliminarily assessed as possible, but requiring further studies.
Słowa kluczowe
Wydawca
Czasopismo
Rocznik
Tom
Strony
539--558
Opis fizyczny
Bibliogr. 19 poz., wykr., tab.
Twórcy
autor
- Katedra Technologii Polimerów, Wydział Chemiczny, Politechnika Gdańska, ul. Gabriela Narutowicza 11/12, 80-222 Gdańsk
autor
- Katedra Technologii Polimerów, Wydział Chemiczny, Politechnika Gdańska, ul. Gabriela Narutowicza 11/12, 80-222 Gdańsk
autor
- Wydział Lekarski, Gdański Uniwersytet Medyczny, ul. Marii Skłodowskiej-Curie 3a, 80-210 Gdańsk
autor
- Katedra Technologii Polimerów, Wydział Chemiczny, Politechnika Gdańska, ul. Gabriela Narutowicza 11/12, 80-222 Gdańsk
autor
- Katedra Technologii Polimerów, Wydział Chemiczny, Politechnika Gdańska, ul. Gabriela Narutowicza 11/12, 80-222 Gdańsk
Bibliografia
- [1] Dhillon K S, Singh J and Lyall J S 2011 A new horizon into the pathobiology, etiology and treatment of migraine Med. Hypotheses 77 147–51
- [2] Steinmetz J D, Seeher K M, Schiess N, Nichols E, Cao B, Servili C, Cavallera V, Cousin E, Hagins H, Moberg M E, Mehlman M L, Abate Y H, Abbas J, Abbasi M A, Abbasian M, Abbastabar H, Abdelmasseh M, Abdollahi M, Abdollahi M, Abdollahifar M-A, Abd-Rabu R, Abdulah D M, Abdullahi A, Abedi A, Abedi V, Abeldańo Zuńiga R A, Abidi H, Abiodun O, Aboagye R G, Abolhassani H, Aboyans V, Abrha W A, Abualhasan A, Abu-Gharbieh E, Aburuz S, Adamu LH, Addo I Y, Adebayo O M, Adekanmbi V, Adekiya T A, Adikusuma W, Adnani Q E S, Adra S, Afework T, Afolabi A A, Afraz A, Afzal S, Aghamiri S, Agodi A, Agyemang-Duah W, Ahinkorah B O, Ahmad A, Ahmad D, Ahmad S, Ahmadzade A M, Ahmed A, Ahmed A, Ahmed H, Ahmed J Q, Ahmed L A, Ahmed M B, Ahmed S A, Ajami M, Aji B, Ajumobi O, Akade S E, Akbari M, Akbarialiabad H, Akhlaghi S, Akinosoglou K, Akinyemi R O, Akonde M, Al Hasan S M, Alahdab F, AL-Ahdal T M A, Al-amer R M, Albashtawy M, AlBataineh M T, Aldawsari K A, Alemi H, Alemi S, Algammal A M, Al-Gheethi A A S, Alhalaiqa F A N, Alhassan R K, Ali A, Ali E A, Ali L, Ali M U, Ali M M, Ali R, Ali S, Ali S S S, Ali Z, Alif S M, Alimohamadi Y, Aliyi A A, Aljofan M, et al 2024 Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 Lancet Neurol. 23 344–81
- [3] Wilson J F 2007 Migraine ed C Laine and D R Goldman Ann. Intern. Med. 147 ITC11-1
- [4] Puledda F, Silva E M, Suwanlaong K and Goadsby P J 2023 Migraine: from pathophysiology to treatment J. Neurol. 270 3654–66
- [5] Gould G M 1904 The History and Etiology of “Migraine” JAMA J. Am. Med. Assoc. XLII 239
- [6] Domitrz I and Kozubski W Standardy leczenia migreny: Polskie Towarzystwo Bólów Głowy
- [7] DOZ.pl 2025 APAP Ice
- [8] Kayabaşoglu G, Altundag A, Kotan D, Dizdar D and Kaymaz R 2017 Osmophobia and olfactory functions in patients with migraine Eur. Arch. Oto-Rhino-Laryngology 274 817–21
- [9] MALE Srinivas Reddy, MANDAPALLI Praveen Kumar, VENGALA Mounika P S L 2019 MIGRAINE RELIEVING TOPICAL PATCH AND ITS PROCESS OF PREPARATION
- [10] Wider B, Pittler M H and Ernst E 2015 Feverfew for preventing migraine Cochrane Database Syst. Rev. 2020
- [11] Koprowska K and Czyż M 2010 Molekularne mechanizmy działania partenolidu – stary lek z nową twarzą Postepy Hig. Med. Dosw. 64 100–14
- [12] Nelson M H, Cobb S E and Shelton J 2002 Variations in parthenolide content and daily dose of feverfew products Am. J. Heal. Pharm. 59 1527–31
- [13] Fuakye E, Hailemeskel B and Fullas F 2024 Migraine Management Using Feverfew, Butterbur, Peppermint, and Ginger: Perspectives of Pharmacy Students Eur. J. Theor. Appl. Sci. 2 412–9
- [14] Bashir S, Hina M, Iqbal J, Rajpar A H, Mujtaba M A, Alghamdi N A, Wageh S, Ramesh K and Ramesh S 2020 Fundamental Concepts of Hydrogels: Synthesis, Properties, and Their Applications Polymers (Basel). 12 2702
- [15] Hoti G, Caldera F, Cecone C, Rubin Pedrazzo A, Anceschi A, Appleton S L, Khazaei Monfared Y and Trotta F 2021 Effect of the Cross-Linking Density on the Swelling and Rheological Behavior of Ester-Bridged β-Cyclodextrin Nanosponges Materials (Basel). 14 478
- [16] Pfaffenrath V, Diener H, Fischer M, Friede M and Henneicke-von Zepelin H 2002 The Efficacy and Safety of Tanacetum Parthenium (Feverfew) in Migraine Prophylaxis - a Double-Blind, Multicentre, Randomized Placebo-Controlled Dose-Response Study Cephalalgia 22 523–32
- [17] Abascal K and Yarnell E L 2015 Tanacetum parthenium (Feverfew)
- [18] Zhan Z-Y, Zhang Z-H, Sun R-H, Wu Y-L, Nan J-X and Lian L-H 2024 A therapeutic strategy of parthenolide in improving imiquimod-induced psoriasis-like skin inflammation targeting IL-36/NETs through skin transdermal therapeutic system Int. Immunopharmacol. 131 111824
- [19] Sabbagh F and Kim B S 2022 Recent advances in polymeric transdermal drug delivery systems J. Control. Release 341 132–46
Uwagi
Opracowanie rekordu ze środków MNiSW, umowa nr POPUL/SP/0154/2024/02 w ramach programu "Społeczna odpowiedzialność nauki II" - moduł: Popularyzacja nauki (2025).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-d8b6a19a-8407-45ba-bdcd-6f2132f3974f
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.