An Optimal Framework for the Effective Delivery of the Radiation to the target by Considering the Case of Head and Neck Cancer

• Autorzy: Singh Pushpendra , Dewangan Naveen Kumar , Potdar Ravindra Manohar , Singh Seema , Mishra Alka , Mishra Santosh Kumar

Identyfikatory

DOI

10.2478/pjmpe-2024-0016

• Języki publikacji: EN

Abstrakty

EN

Introduction: Delivering the required dose to the intended target while limiting the radiation's impact on adjacent normal tissue is the principal goal of radiotherapy. One effective method for doing this is intensity-modulated radiotherapy, which operates on the idea of inverse planning. In order to transmit the fluence to the target efficiently while sparing the healthy cells, the objective of the research is to generate the ideal radiation dosage by first optimizing the fluence and then adjusting the trajectory of the leaf. Materials and Methods: Fluence mapping is utilized in inverse planning to calculate each beam's intensity level. Considering dose-volume limitations on the OARs, five evenly spaced beams expose the intended target for examination. The efficacy of the therapy regimens was measured using cumulative DVH. We have taken into account a number of PTVs and OARs acquired from the CORT dataset, which is accessible publicly for the benefit of researchers, to validate our approach. Results: For the various target area and critical organs, we fixed the radiation levels at 82 Gy and 61 Gy across the PTV-70 and PTV-56, and similarly, the dose volumes of 52 Gy, 40 Gy, and 32 Gy across the Spinal Cord, Spinal Cord PRV, and Left and Right Parotid. Analysis of the data indicates that our approach generates the highest D95 dosage level possible across the target area for each PTV. Additionally, relative to other approaches employed in the literature, our approach's duration for analysis (254.28 Seconds) is extremely low. Conclusion: The suggested approach can produce global minima for IMRT planning with consistent quality across a range of treatment plans and effectively improve safety for substantial dual OARs.

Słowa kluczowe

EN

fluence map optimization; planned target volume; radiotherapy; leaf trajectory optimization

• Wydawca: Polskie Towarzystwo Fizyki Medycznej
• Czasopismo: Polish Journal of Medical Physics and Engineering
• Rocznik: 2024
• Tom: Vol. 30, Iss. 3
• Strony: 132--144
• Opis fizyczny: Bibliogr. 49 poz., rys., tab.

Twórcy

autor

Singh Pushpendra

• Department of Electronics & Telecommunication Engineering, Bhilai Institute of Technology, Durg, India

• https://orcid.org/0000-0001-8608-5188

autor

Dewangan Naveen Kumar

• Department of Electronics & Telecommunication Engineering, Bhilai Institute of Technology, Durg, India

• https://orcid.org/0009-0007-0911-5161

autor

Potdar Ravindra Manohar

• Department of Electronics & Telecommunication Engineering, Bhilai Institute of Technology, Durg, India

• https://orcid.org/0000-0002-7297-5945

autor

Singh Seema

• Department of Electronics & Telecommunication Engineering, Shri Shankaracharya Technical Campus, Bhilai, Chhattisgarh, India

• https://orcid.org/0009-0002-8750-2590

autor

Mishra Alka

• Department of Electrical & Electronics Engineering, Bhilai Institute of Technology, Durg, India

• https://orcid.org/0000-0002-8997-6581

autor

Mishra Santosh Kumar

• Department of Mechanical Engineering, Bhilai Institute of Technology, Durg, India

• https://orcid.org/0000-0001-8616-2606

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa nr POPUL/SP/0154/2024/02 w ramach programu "Społeczna odpowiedzialność nauki II" - moduł: Popularyzacja nauki (2025).