Nanoscale dosimetric consequences around bismuth, gold, gadolinium, hafnium, and iridium nanoparticles irradiated by low energy photons

• Autorzy: Mesbahi Asghar , Mansouri Elham , Mohammadzadeh Mohammad

Identyfikatory

DOI

10.2478/pjmpe-2020-0027

• Języki publikacji: EN

Abstrakty

EN

In the current study, nanoscale physical dose distributions around five potential nanoparticles were compared. Five potential nanoparticles including bismuth, gold, gadolinium, hafnium, and iridium nanoparticles in the form of a sphere with a diameter of 50 nm were simulated in a water medium. The MCNPX (2.7.0) Monte Carlo code with updated libraries was used for calculations of electron dose deposition and electron flux in water from 25 nm up to 4000 nm with a step of 25 nm. Also, secondary electron spectra after irradiation of nanoparticles with mono-energetic photons with energies of 30, 60, 100 keV were derived. The nano-scale distance-dose curves showed a very steep gradient with distance from nanoparticle surface up to 60 nm and after this point, a gradual decrease was seen. The dose deposition characteristics in the nano-scale were dependent on the type of nanoparticle as well as photon energy. Our results concluded that for each photon energy in the energy range of 30-100 keV, a suitable nanoparticle can be selected to boost the effect of energy deposition by low energy photon beams used in brachytherapy.

Słowa kluczowe

EN

nanoparticle; radiation therapy; electron spectra; heavy atoms

• Wydawca: Polskie Towarzystwo Fizyki Medycznej ; De Gruyter
• Czasopismo: Polish Journal of Medical Physics and Engineering
• Rocznik: 2020
• Tom: Vol. 26, Iss. 4
• Strony: 225--234
• Opis fizyczny: Bibliogr. 35 poz., rys.

Twórcy

autor

Mesbahi Asghar

• Molecular Medicine Research Center, Biomedicine Institute, Tabriz University of Medical Sciences, Iran
• Medical Radiation Sciences Research Team, Tabriz University of Medical Sciences, Iran

autor

Mansouri Elham

• Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

autor

Mohammadzadeh Mohammad

• Medical Radiation Sciences Research Team, Tabriz University of Medical Sciences, Iran

Bibliografia

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2021).