J-PET application as a Compton camera for proton beam range verification: A preliminary study

Kozani, Majid; Rucinski, Antoni; Moskal, Pawel

doi:10.5604/01.3001.0054.1819

Artykuł - szczegóły

Tytuł artykułu

J-PET application as a Compton camera for proton beam range verification: A preliminary study

Autorzy

Kozani Majid , Rucinski Antoni , Moskal Pawel

Wybrane pełne teksty z tego czasopisma

Identyfikatory

DOI

10.5604/01.3001.0054.1819

Warianty tytułu

Języki publikacji

Abstrakty

Hybrid in-beam PET/Compton camera imaging currently shows a promising approach to use of the quasi-real-time range verification technique in proton therapy. This work aims to assess the capability of utilizing a configuration of the Jagiellonian-positron emission tomography (J-PET) scanner made of plastic scintillator strips, so as to serve as a Compton camera for proton beam range verification. This work reports the production yield results obtained from the GATE/Geant4 simulations, focusing on an energy spectrum (4.2-4.6) MeV of prompt gamma (PG) produced from a clinical proton beam impinging on a water phantom. To investigate the feasibility of J-PET as a Compton camera, a geometrical optimisation was performed. This optimisation was conducted by a point spread function (PSF) study of an isotropic 4.44 MeV gamma source. Realistic statistics of 4.44 MeV PGs obtained from the prior step were employed, simulating interactions with the detector. A sufficient number of detected photons was obtained for the source position reconstruction after performing a geometry optimisation for the proposed J-PET detector. Furthermore, it was demonstrated that more precise calculation of the total deposited energy of coincident events plays a key role in improving the image quality of source distribution determination. A reasonable spatial resolution of 6.5 mm FWHM along the actual proton beam direction was achieved for the first imaging tests. This preliminary study has shown notable potential in using the J-PET application for in-beam PET/Compton camera imaging at quasi-real-time proton range monitoring in future clinical use.

Słowa kluczowe

proton therapy prompt gammas Compton camera J-PET range verification

Wydawca

Uniwersytet Jagielloński - Collegium Medicum
Index Copernicus Sp. z o.o.

Czasopismo

Bio-Algorithms and Med-Systems

Rocznik

2023

Tom

Vol. 19, no. 1

Strony

23--30

Opis fizyczny

Bibliogr. 64 poz., rys.

Twórcy

autor

Kozani Majid

Department of Radiology, University of Pennsylvania, Philadelphia, USA
Institute of Nuclear Physics Polish Academy of Sciences, Krakow, Poland

https://orcid.org/0000-0002-7460-3926

autor

Rucinski Antoni

Institute of Nuclear Physics Polish Academy of Sciences, Krakow, Poland

https://orcid.org/0000-0002-5815-4606

autor

Moskal Pawel

Center for Theranostics, Jagiellonian University, Krakow, Poland

https://orcid.org/0000-0002-4229-3548

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Uwagi

Opracowanie rekordu ze środków MEiN, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2022-2023).

Typ dokumentu

Bibliografia

Identyfikator YADDA

bwmeta1.element.baztech-d7228ff1-f329-4a04-a074-145be1a481ec