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Synthesis, Spectral Studies, Antibacterial and Antifungal Activity of 2" – Methoxy - 4" -[2 - (4' -chlorophenyl)-6-Methyl Imidazo [1, 2-a] Pyridin-3-yl]-6"-Aryl Nicotinonitrile

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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Pyridine nucleus plays an important role in medicine, agriculture and industrial chemistry. With a view of biological activities and variety of industrial applications, some new 2" – methoxy - 4" - [2 - ( 4' -chlorophenyl)-6-methyl imidazo [1, 2-a] pyridin-3-yl]-6"-aryl nicotinonitrile( 4a-4l ) has been synthesized. The products have been assayed for their biological activity against Gram +ve, Gram –ve bacteria and fungi. Some of the products showed moderate activity in concentration 50µg/ml. The structures of the products have been elucidated by IR, 1H-NMR, Mass spectral data, elemental analysis and thin layer chromatography.
Rocznik
Tom
Strony
155--160
Opis fizyczny
Bibliogr. 13 poz., rys., tab., wz.
Twórcy
autor
  • Shree M. & N. Virani science college, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India.
  • Shree M. & N. Virani science college, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India.
  • Shree M. & N. Virani science college, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India.
  • Shree M. & N. Virani science college, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India.
Bibliografia
  • [1]. D. B. Shinde, M. S. Shingare; Indian J. Chem., 30B, 450, 1991.
  • [2]. G. A. Kileigil and R. Ertan; J. Heterocycl. Chem., 35, 1485, 1998.
  • [3]. Saheyla Ozbey and Engin Kendi; J. Heterocycl. Chem., 35, 1485, 1998.
  • [4]. N. Latif, N. Mishrky and N. S. Girgis; Indian J. Chem., 20B, 147-149, 1981.
  • [5]. W. Von Behenburg, J. Engel, J. Heese and K. Thiele; Ger. often., D.E.,3, 337, 593 (Cl C07D 213/72) 1984; Chem. Abstr., 101, 130595n, 1984.
  • [6]. L. Castedo, J. M. Quintela and R. Riguers; Eur. J. Med. Chem. Chim. Ther., 19(6), 555, 1984; Chem. Abstr., 103, 37337, 1985.
  • [7]. M. R. Pavia, C. P. Taylor, F. M. Hershenson and S. J. Lobbestael; J. Med. Chem., 30, 1210, 1987.
  • [8]. W. L. Hoefling, D. Elhaner and E. Reckling; VEB Leund-Werke “Walter Ulbricht” Ger., 1,193, 506, 1965; Chem. Abstr., 63, 6979, 1965.
  • [9]. Thiele Kurt, Von Be Benburg and E. Walter; S. African 6, 905, 06, 13 Feb.,1970.
  • [10]. B. John E.D., F. M. Peter and Freeman; Ger. often., 2, 029, 079 (Cl. A 01 N007d), 1971; Brist. Appl. (1969); Chem . Abstr., 74, 99891d, 1971.
  • [11]. V. Scott and Joseph; Jap. Pat., 2, 803, 592, 1979; Chem. Abstr., 92, 47216, 1980.
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  • [13]. A. L. Barry; the antimicrobial acceptability test, principal and practices, edited by illus lee and febiger; 180, Bio. Abstr., 64, 25183,1997.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-d5e7c046-cb0d-43e3-8be7-825505cd61b1
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