Scavenging activity, anti-inflammatory and diabetes related enzyme inhibition properties of leaves extract from some varieties of Phoenyx dactylifera l.

Eddine, L. S.; Segn, L.; Noureddine, G.; Mohammed Redha, O.; Mokni, Sonia

Artykuł - szczegóły

Tytuł artykułu

Scavenging activity, anti-inflammatory and diabetes related enzyme inhibition properties of leaves extract from some varieties of Phoenyx dactylifera l.

Autorzy

Eddine L. S. , Segn L. , Noureddine G. , Mohammed Redha O. , Mokni Sonia

Treść / Zawartość

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Abstrakty

In this study we investigate the antioxidant, anti-inflammatory, and antidiabetic activities of ethanolic leaves extracts of three selected varieties of Phoenyx dactylifera L. namely: “Ghars”, “Deglet Nour” and “Hamraya”. The assessment of the antioxidant potential of crude leaves extracts, using superoxide anions inhibition, DPPH and total antioxidant activity essays, was carried out. Furthermore, the anti-inflammatory properties of the extracts were determined by measuring the inhibition of nitric oxide (NO) production. Moreover, the antidiabetic effect was evaluated by inhibition of α-amylase enzymes. The total phenolic content measured by Folin-ciocalteu method was as well conducted. The raw leaves extracts of the selected varieties was found to contain a high content of total phenolic content (342.45 mg GAE/gDW for GE) and therefore exhibited a higher antioxidant activity and inhibitory effect of radicals scavenging activity against DPPH and superoxide anion (IC50 = 7.44 μg/mL and 39.11 μg/mL respectively). The three varieties exhibited significant inhibition nitric oxide using in-vitro assay (IC50 = 240.28 μg/mL for GE). The extracts also displayed high inhibition actions against α-amylase enzymes. The results suggest that the leaves of the three selected varieties of Phoenyx dactylifera can be considered as a good source of natural antioxidant and anti-inflammation drugs as well as potent antidiabetic medicine.

Słowa kluczowe

Phoenyx dactylifera L phenolic content leaves extract Scavenger activity anti-inflammatory antidiabetic

Wydawca

Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"

Czasopismo

International Letters of Chemistry, Physics and Astronomy

Rocznik

2013

Tom

Vol. 9, iss. 2

Strony

125--135

Opis fizyczny

Bibliogr. 50 poz., wykr., wz.

Twórcy

autor

Eddine L. S.

Salah_laouini@yahoo.fr

Department of Industrial Chemistry, Mohammed Kheider University, Biskra, Algeria
Laboratory of Valorisation and Technology of Saharian Resources, El-Oued University, Algeria

autor

Segn L.

Process Engineering Laboratory, Kasdi Merbah University, Ouargla, Algeria

autor

Noureddine G.

Laboratory of Biomolecules and Plant Breeding, Larbi Ben M’hidi University, Algeria

autor

Mohammed Redha O.

Process Engineering Laboratory, Kasdi Merbah University, Ouargla, Algeria

autor

Mokni Sonia

Laboratory of Wastewater Treatment, Water Researches and Technologies, Tunisia

Bibliografia

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Typ dokumentu

Bibliografia

Identyfikator YADDA

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