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Tytuł artykułu

Chitosan-based films with selected moisturizing additives

Treść / Zawartość
Identyfikatory
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
This study presents the development and characterization of thin films based on chitosan, modified with selected moisturizing additives, including hyaluronic acid, snail mucus extract, natural moisturizing factor (NMF), and gluconolactone, chosen for their common application in skin care products. Chitosan was dissolved in 0.1 M acetic acid to prepare a 1% w/v solution, and each additive was incorporated at 10% w/w relative to the chitosan content, both individually and in combination. The resulting mixtures were cast and dried under ambient conditions to form flexible films. Comprehensive characterization was performed using Fourier Transform Infrared Spectroscopy (FTIR), atomic force microscopy (AFM), contact angle measurements, and mechanical testing. The results revealed significant differences in chemical interactions, surface morphology, wettability, and mechanical behavior depending on the additive used. Notably, the formulation combining all moisturizing agents exhibited the most favorable balance of mechanical strength, flexibility, and hydration-related surface characteristics. FTIR spectra indicated molecular-level interactions between chitosan and the additives, particularly through hydrogen bonding. AFM analysis showed variations in surface roughness, while contact angle measurements highlighted changes in surface energy and hydrophilicity. These findings indicate that the modified chitosan films are promising candidates for innovative, sustainable dermatological and cosmetic applications, especially for effective skin hydration and use in skin care products.
Rocznik
Strony
art. no. 9
Opis fizyczny
Bibliogr. 20 poz., rys., tab., wykr., zdj.
Twórcy
  • Nicolaus Copernicus University in Torun, Faculty of Chemistry, Laboratory for Functional Polymeric Materials, Gagarin 7, 87-100 Torun, Poland
  • Nicolaus Copernicus University in Torun, Faculty of Chemistry, Laboratory for Functional Polymeric Materials, Gagarin 7, 87-100 Torun, Poland
autor
  • Nicolaus Copernicus University in Torun, Faculty of Chemistry, Laboratory for Functional Polymeric Materials, Gagarin 7, 87-100 Torun, Poland
Bibliografia
  • [1] Martins A. M., Marto J. M.: A sustainable life cycle for cosmetics: From design and development to post-use phase. Sustain. Chem. Pharm. 35 (2023) 101178.
  • [2] Cubas A. L.V., Bianchet R. T., dos Reis I. M.A. S., Gouveia I. C.: Plastics and microplastic in the cosmetic industry: Aggregating sustainable actions aimed at alignment and interaction with UN sustainable development goals. Polymers (Basel) 14 (2022) 4576.
  • [3] Yousaf S. S., Houacine C., Khan I., Ahmed W., Jackson M. J.: Importance of biomaterials in biomedical engineering. In: Advances in Medical and Surgical Engineering. Elsevier (2020) 151–177.
  • [4] Coltelli M.-B., Danti S., Trombi L., Morganti P., Donnarumma G., BaroniA., FuscoA., LazzeriA.: Preparation of innovative skin compatible films to release polysaccharides for biobased beauty masks. Cosmetics 5 (2018) 70.
  • [5] Wang H., Qian J., Ding F.: Emerging chitosan-based films for food packaging applications. J. Agric. Food Chem. 66 (2018) 395–413.
  • [6] Ahmad S. I., Ahmad R., Khan M. S., Kant R., Shahid S., Gautam L., Hasan G. M., Hassan M. I.: Chitin and its derivatives: Structural properties and biomedical applications. Int. J. Biol. Macromol. 164 (2020) 526–539.
  • [7] Bukhari S. N.A., Roswandi N. L., Waqas M., Habib H., Hussain F., Khan S., Sohail M., Ramli N. A., Thu H. E., Hussain Z.: Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects. Int. J. Biol. Macromol. 120 (2018) 1682–1695.
  • [8] Dicker K. T., Gurski L. A., Pradhan-Bhatt S., Witt R. L., Farach-Carson M. C., Jia X.: Hyaluronan: A simple polysaccharide with diverse biological functions. Acta Biomater. 10 (2014) 1558–1570.
  • [9] Valachová K., Šoltés L.: Self-associating polymers chitosan and hyaluronan for constructing composite membranes as skin-wound dressings carrying therapeutics. Molecules 26 (2021) 2535.
  • [10] Altay B. N., Ma R., Fleming P. D., Joyce M. J., Anand A., Chen T., Keskin B., Maddipatla D., Turkani V. S., Kotkar P. R., Fleck A., Rasheed R., He D.: Surface free energy estimation: A new methodology for solid surfaces. Adv. Mater. Interfaces 7 (2020).
  • [11] Chen G., Mi J., Wu X., Luo C., Li J., Tang Y., Li J.: Structural features and bioactivities of the chitosan. Int. J. Biol. Macromol. 49 (2011) 543–547.
  • [12] Sadat A., Joye I. J.: Peak fitting applied to Fourier transform infrared and Raman spectroscopic analysis of proteins. Appl. Sci. 10 (2020) 5918.
  • [13] Zhang W., Jin X., Li H., Zhang R., Wu C.: Injectable and body temperature sensitive hydrogels based on chitosan and hyaluronic acid for pH sensitive drug release. Carbohydr. Polym. 186 (2018) 82–90.
  • [14] Zhu K., Zhang Z., Li G., Sun J., Gu T., Ain N. U., Zhang X., Li D.: Extraction, structure, pharmacological activities and applications of polysaccharides and proteins isolated from snail mucus. Int. J. Biol. Macromol. 258 (2024) 128878.
  • [15] Rubina M., Elmanovich I., Vasil’kov A.: AFM studies of chitosan, gold-chitosan, and silver-chitosan films morphology. Macromol. Symp. 389 (2020).
  • [16] Lewandowska K., Sionkowska A., Grabska S.: Influence of the intermolecular interaction on physico-chemical properties of chitosan/hyaluronic acid blends. Prog. Chem. Appl. Chitin Deriv. XX (2015) 170–176.
  • [17] Kaczmarek-Szczepańska B., Glajc P., Chmielniak D., Gwizdalska K., Swiontek-Brzezinska M., Dembińska K., ShindeA. H., Gierszewska M., Łukowicz K., Basta-Kaim A., D’Amora U., Zasada L.: Development and characterization of biocompatible chitosan-aloe vera films functionalized with gluconolactone and sorbitol for advanced wound healing applications. ACS Appl. Mater. Interfaces 17 (2025) 15196–15207.
  • [18] Aguirre-Loredo R. Y., Rodríguez-Hernández A. I., Morales-Sánchez E., Gómez-Aldapa C. A., Velazquez G.: Effect of equilibrium moisture content on barrier, mechanical and thermal properties of chitosan films. Food Chem. 196 (2016) 560–566.
  • [19] Jost V.: Mechanical and permeation properties of PHA-based blends and composites. In: The Handbook of Polyhydroxyalkanoates. CRC Press (2020) 137–164.
  • [20] El-Banna F. S., Mahfouz M. E., Leporatti S., El-Kemary M., Hanafy N. A.N.: Chitosan as a natural copolymer with unique properties for the development of hydrogels. Appl. Sci. 9 (2019) 2193.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-d43553c8-3985-4b76-8a18-da6754aa66ea
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