The study of the influence of micro-environmental signals on macrophage differentiation using a quantitative Petri net based model

• Autorzy: Rżosińska K. , Formanowicz D. , Formanowicz P.

Identyfikatory

DOI

10.1515/acsc-2017-0022

• Języki publikacji: EN

Abstrakty

EN

The complexity of many biological processes, which, thanks to the development of many fields of science, becomes for us more and more obvious, makes these processes extremely interesting for further analysis. In this paper a quantitative model of the process of macrophage differentiation, which is essential for many phenomena occurring in the human body, is proposed and analyzed. The model is expressed in the language of Petri net theory on the basis of one of the three hypotheses concerning macrophage differentiation existing in the literature. The performed analysis allowed to find an importance of individual factors in the studied phenomenon.

Słowa kluczowe

EN

Petri nets; atherosclerosis; macrophages; t-invariants

• Wydawca: Polish Academy of Sciences, Committee of Automatic Control and Robotics
• Czasopismo: Archives of Control Sciences
• Rocznik: 2017
• Tom: Vol. 27, no. 2
• Strony: 331--349
• Opis fizyczny: Bibliogr. 29 poz., rys., schem., tab.

Twórcy

autor

Rżosińska K.

• Institute of Computing Science, Poznań University of Technology, Piotrowo str. 2, 60-965 Poznan, Piotrowo

autor

Formanowicz D.

• department of Clinical Biochemistry and laboratory Medicine, Poznan University of Medical Sciences, Grunwaldzka str. 6, 60-780 Poznan, Poland

autor

Formanowicz P.

• Institute of Computing Science, Poznan University of Technology, Piotrowo str. 2, 60-965 Poznan
• Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego str. 12/14, 61-704 Poznan, Poland

Bibliografia

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Uwagi

PL

Opracowanie ze środków MNiSW w ramach umowy 812/P-DUN/2016 na działalność upowszechniającą naukę (zadania 2017).