CFD modeling of droplet generation process for medical applications using the electrostatic impulse method

• Autorzy: Cendrowski Piotr , Kramek-Romanowska Katarzyna , Lewińska Dorota , Grzeczkowicz Marcin , Korycka Paulina , Krzysztoforski Jan

Identyfikatory

DOI

10.24425/cpe.2022.142278

• Języki publikacji: EN

Abstrakty

EN

The electrostatic impulse method is an established method for producing microbeads or capsules. Such particles have found application in biomedical engineering and biotechnology. The geometric properties of the droplets – constituting precursors of microbeads and capsules – can be precisely controlled by adjusting the geometry of the nozzle system, the physical properties and the flow rate of the fluids involved, as well as the parameters of the electrostatic impulse. In this work, a method of mathematical modeling of the droplet generation process using the electrostatic impulse method in a single nozzle system is presented. The developed mathematical model is an extension of the standard Volume of Fluid (VOF) model by addition of the effect of the electric field on the fluid flow. The model was implemented into the OpenFOAM toolkit for computational fluid dynamics (CFD). The performed CFD simulation results showed good agreement with experimental data. As a result, the influence of all process parameters on the droplet generation process was studied. The most significant change in droplet generation was caused by changing the electrostatic impulse strength. The presented modeling method can be used for optimization of process design and for studying the mechanisms of droplet generation. It can be extended to describe multi nozzle systems used for one-step microcapsule production.

Słowa kluczowe

EN

droplet generation; electrostatic impulse method; encapsulation; CFD; OpenFOAM

PL

generacja kropli; metoda impulsu elektrostatycznego; kapsułkowanie; Kontrakty CFD; OpenFOAM

• Wydawca: Komitet Inżynierii Chemicznej i Procesowej Polskiej Akademii Nauk
• Czasopismo: Chemical and Process Engineering
• Rocznik: 2022
• Tom: Vol. 43, nr 3
• Strony: 331--–355
• Opis fizyczny: Bibliogr. 68 poz., rys., tab.

Twórcy

autor

Cendrowski Piotr

• Warsaw University of Technology, Faculty of Chemical and Process Engineering, Ludwika Waryńskiego 1, Warsaw, Poland

• https://orcid.org/0000-0002-5089-8811

autor

Kramek-Romanowska Katarzyna

• Warsaw University of Technology, Faculty of Chemical and Process Engineering, Ludwika Waryńskiego 1, Warsaw, Poland

• https://orcid.org/0000-0001-9969-0360

autor

Lewińska Dorota

• Nalecz Institute of Biocybernetics and Biomedical Engineering Polish Academy of Sciences, Ks. Trojdena 4, Warsaw, Poland

• https://orcid.org/0000-0002-9978-9157

autor

Grzeczkowicz Marcin

• Nalecz Institute of Biocybernetics and Biomedical Engineering Polish Academy of Sciences, Ks. Trojdena 4, Warsaw, Poland

• https://orcid.org/0000-0001-8775-6940

autor

Korycka Paulina

• Foundation of Research and Science Development, Rydygiera 8, 01-793 Warsaw, Poland

• https://orcid.org/0000-0003-1148-7910

autor

Krzysztoforski Jan

• Warsaw University of Technology, Faculty of Chemical and Process Engineering, Ludwika Waryńskiego 1, Warsaw, Poland

• https://orcid.org/0000-0002-6869-1595

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