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In this work the studies on the antioxidative properties of extracts from various morphotic parts of the ground elder (leaves, rhizomes, seeds and flowers) were presented. Moreover, the effect of different extraction methods (ultrasonic assisted extractions, extraction in a Soxhlet apparatus, extraction at the boiling point of the solvent used), solvent and its amount, and extraction time on the antioxidative properties of the obtained extracts were tested. The studies showed that all parts of ground elder can show radical scavenging activity, and it depends mainly on the method of extraction and extraction time. But the most beneficial is ultrasonic assisted extraction which used lower amount of solvent (ethanol). In case of all parts of the ground elder (leaves, rhizomes, seeds and flowers) it allows to obtain very high values of the antioxidant capacity (above 90%) for very short extraction time amounted to 20–40 minutes.
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13--18
Opis fizyczny
Bibliogr. 32 poz., rys., tab.
Twórcy
autor
- West Pomeranian University of Technology, Szczecin, 71-065, Szczecin, Poland
autor
- Pomeranian Medical University, 71-460, Szczecin, Poland
autor
- West Pomeranian University of Technology, Szczecin, 71-065, Szczecin, Poland
autor
- West Pomeranian University of Technology, Szczecin, 71-065, Szczecin, Poland
autor
- West Pomeranian University of Technology, Szczecin, 71-065, Szczecin, Poland
autor
- Pomeranian Medical University, 71-460, Szczecin, Poland
Bibliografia
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- 3. Rahal, A., Kumar, A., Singh, V., Yadav, B., Tiwari, R., Chakraborty, S. & Dham, K. (2014). Oxidative stress, prooxidants, and antioxidants: the interplay. Biomed. Res. Int. Article ID 761264, 1–19. DOI: 10.1155/2014/761264.
- 4. Chen, Z. & Zhong, C. (2014). Oxidative stress in Alzheimer’s disease. Neurosci Bull. 30(2), 271–281. DOI: 10.1007/s12264-013-1423-y.
- 5. Gupta, R.K., Patel, A.K., Shah, N., Chaudhary, A.K., Jha, U.K., Yadav, U.C., Gupta, P.K. & Pakuwal. U. (2014).Oxidative stress and antioxidants in disease and cancer: a review. Asian Pac. J. Cancer. Prev. 15(11), 4405–4409. DOI: 7314/APJCP.2014.15.11.4405.
- 6. Hauser, D.N. & Hastings, T.G. (2013). Mitochondrial dysfunction and oxidative stress in Parkinson’s disease and monogenic parkinsonism. Neurobiol. Dis. 51, 35–42. DOI: 10.1016/j.nbd.2012.10.011.
- 7. Rains, J.L. & Jain, S.K. (2011). Oxidative stress, insulin signaling, and diabetes. Free Radic. Biol. Med. 50(5), 567–575. DOI: 10.1016/j.freeradbiomed.2010.12.006.
- 8. Siti, H.N., Kamisah, Y. & Kamsiah, J. (2015). The role of oxidative stress, antioxidants and vascular infl ammation in cardiovascular disease (a review). Vascul Pharmacol. 71, 40–56. DOI: 10.1016/j.vph.2015.03.005.
- 9. Cisowski, W. (1985). Flavonoid compounds in herb Aegopodium podagraria L. Herba Pol. 31 (3–4), 137–140.
- 10. Nowak, B. (2000). Leksykon roślin ozdobnych i użytkowych (wyd. 1). Warszawa, Polska: Wiedza Powszechna.
- 11. Stefanovic, O., Comic, L., Stanojevic, D., Čomić, L. (2009). Antibacterial activity of Aegopodium podagraria L. extracts and interaction between extracts and antibiotics. Turk. J. Biol. 33, 145–150. DOI: 10.3906/biy-0810-21.
- 12. Trąba, C., Rogut, K., Wolański, P. (2012). Wild plants and their use. Guide to selected species. Rzeszów, Polska: Procapathia.
- 13. Kunstman, P., Wojcińska, M. & Popławska, P. (2012). Podagrycznik pospolity (Aegopodium podagraria L.) Post Fitot. 4, 244–249.
- 14. Orav, A., Viitak, A. & Vaher, M. (2010). Identifi cation of bioactive compounds in the leaves and stems of Aegopodium podagraria by various analytical techniques. Procedia Chem. 2, 152–160. DOI: 10.1016/j.proche.2009.12.022.
- 15. Priori, N.M., Lundgaard, N.H., Light, M.E., Stafford, G.I., van Staden, J. & Jäger, A.K. (2007). The polyacetylene falcarindiol with COX-1 activity isolated from Aegopodium podagraria L. J. Ethnopharmacol. 113, 176–178. DOI: 10.1016/j.jep.2007.05.005.
- 16. Akhtardzhiev, K.H., Nakov, N. & Nikolov, V. (1975). Content of fl avonoids in Aegopodium podagraria. Farmatsiya. 25 (1), 24–27.
- 17. Kapetanos, C., Karioti, A. & Bojović, S. et al. (2008). Chemical and principal-component analyses of the essential oils of Apioideae Taxa (Apiaceae) from Central Balkan. Chem. Biodivers. 5 (1), 101–119. DOI: 10.1002/cbdv.200890000.
- 18. Koyro, O.O. (2013). Role of goutweed (Aegopodium podagraria L.) biologically active substances in nephroprotective, hepatoprotective and hypouricemic activity. PhD thesis. Kharkiv – National University of Pharmacy. Ukraine.
- 19. Ojala, T. (2001). Biological screening of plant coumarins. Academic dissertation, University of Helsinki, Finland.
- 20. Paramonov, E.A., Khalilova, A.Z., Odinokov, V.N. & Khalilov, L.M. (2000). Identifi cation and biological activity of volatile organic compounds isolated from plants and insects. III. Chromatography-mass spectrometry of volatile compounds of Aegopodium podagraria. Chem Nat Comp. 36 (6), 584-586. DOI: 10.1023/A:1017563708858
- 21. Ojala, T., Remes, S., Haansuu, P., Vuorela, H., Hiltunen, R., Haahtela, K., Vuorela, P. (2000). Antimicrobial activity of some coumarin containing herbal plants growing in Finland. J. Ethnopharmacol. 73, 299–305. DOI: 10.1016/S0378-8741(00)00279-8.
- 22. Tovchiga, O.V. (2009). The investigation of the goutweed (Aegopodium podagraria L.) diuretic, nephroprotective and hypouricemic action as the basis for the drug development. PhD thesis. Kharkiv – National University of Pharmacy. Ukraine.
- 23. Tovchiga, O.V. (2012). The influence of goutweed (Aegopodium podagraria L.) preparations on the metabolic processes in alloxan-induced diabetic mice. Pharmacol. Med. Toxicol. 5, 73–78.
- 24. Tovchiga, O.V. (2016). The influence of goutweed (Aegopodium podagraria L.) tincture and metformin on the carbohydrate and lipid metabolism in dexamethasone-treated rats. BMC Complement. Altern. Med. 16, 235. DOI: 10.1186/s12906-016-1221-y.
- 25. Tovchiga, O.V., Shtrygol, S.Y., Taran, A.V. & Yudkevich, T.K. (2016). The renal effects of the goutweed (Aegopodium podagraria L.) tincture and metformin in dexamethasone-treated rats. Clinical Pharmacy. 20 (4), 39–45. DOI: 10.24959/cphj.16.1407.
- 26. Tovchiga, O.V. & Shtrygol, S.Y. (2016). The effect of medicines with goutweed (Aegopodium podagraria L.) on the physical endurance, cognitive functions and the level of depression in animals. News of pharmacy. 1 (85), 71–76. DOI: 10.24959/nphj.16.2100.
- 27. Tovchiga, O.V. (2017). The effects of goutweed (Aegopodium podagraria L.) preparations on glycemia in intact rats and against the background of metformin. News of Pharmacy. 2(90), 54–62. DOI: 10.24959/nphj.17.2161.
- 28. Tovchiga, O.V. (2016). Interaction of Aegopodium podagraria L. (goutweed) preparations with central nervous system depressants. Ukrainian Biopharmac. J. 1 (42), 31–36. DOI: 10.24959/ubphj.16.6.
- 29. Valyova, M., Tashev, A., Stoyanov, S., Yordanova, S. & Ganeva, Y. (2016). In vitro free-radical scavenging activity of Aegopodium podagraria L. and Orlaya grandifl ora (L.) Hoffm. (Apiaceae). J. Chem. Technol. Metallurgy. 51 (3), 271–274.
- 30. Akhtardzhiev, K., Nakov, N. & Nikolov, V. (1975). Content of fl avonoids in Aegopodium podagraria. Farmatsiya. 25 (1), 24–27.
- 31. Jakubczyk, K., Kwiatkowski, P., Sienkiewicz, M. & Janda, K. (2018). The content of polyphenols in extract from goutweed (Aegopodium podagraria L.) and their antistaphylococcal activity. Post Fitoter (1), 3–9, https://doi.org/10.25121/PF.2018.19.1.3 (in Polish).
- 32. Šircelj, H., Mikulic-Petkovsek, M., Veberic, R., Hudina, M. & Slatnar, A.(2018). Lipophilic antioxidants in edible weeds from agricultural areas. Turk. J. Agric. For. (42), 1–10.
Uwagi
Opracowanie rekordu w ramach umowy 509/P-DUN/2018 ze środków MNiSW przeznaczonych na działalność upowszechniającą naukę (2019).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-cf1bfa67-f003-4a5f-aadb-cca0f9c37469