Artificial heart: Hydrophobic coating to make it more natural

• Autorzy: Ziętek P. A. , Butruk B. , Ciach T.
• Języki publikacji: EN

Abstrakty

EN

Polyurethanes are biocompatible materials commonly used in medical applications, mainly as coatings for vascular grafts and artificial hearts. There are many methods to increase hemocompatibility of polyurethane surfaces. Presented study was undertaken to obtain hydrophobic polyurethane coatings by silicone and perfl uorocarbohydrate modification. The aim of this work was to obtain smooth and homogenous coatings, as porous materials are likely to cause blood coagulation. Surface analysis (IR spectroscopy and scanning acoustic microscopy) revealed that the applied method allows to modify polyurethane surface successfully. An increase in material hydrophobicity was confirmed contact angle measurement.

Słowa kluczowe

EN

hydrophobic coatings; polyurethane vascular devices; blood coagulation

• Wydawca: Foundation for Young Scientists
• Czasopismo: Challenges of Modern Technology
• Rocznik: 2011
• Tom: Vol. 2, no. 3
• Strony: 15--19
• Opis fizyczny: Bibliogr. 7 poz., rys., wykr.

Twórcy

autor

Ziętek P. A.

• Warsaw University of Technology, Faculty of Chemical and Process Engineering, ul. Warynskiego 1, 00-645 Warszawa, Poland

autor

Butruk B.

autor

Ciach T.

Bibliografia

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• [2] Berg, J.M., J.L. Tymoczko, and L. Stryer. Biochemia. Warszawa: Wydawnictwo Naukowe PWN, 2005.
• [3] Turbill, P., T. Beugeling, and A.A. Poot. “Proteins involved in the Vroman effect during exposure of human blood plasma to glass and polyethylene”. Biomaterials 17(13), 1996: 1279–1287.
• [4] Gorbet, M.B., and M.V. Sefton. “Biomaterial-associated thrombosos: roles of coagulation factors, compulement, platelets and leukocytes”. Biomaterials 25(26), 2004: 5681–5703.
• [5] Xue, L., and H.P. Greisler. “Biomaterials in the development and future of vascular grafts”. Journal of Vascular Surgery 37(2), 2003: 472–480.
• [6] Resiak, I., and G. Rokicki. “Modyfikowane poliuretany do zastosowań biomedycznych”. Polimery 45(9), 2000: 592–602 [In Polish].
• [7] Dabagh, M., M.J. Abdekhodaie, and M.T. Kh orasani. “Effects of polydimethylsiloxane grafting on the calcification, physical properties, and biocompatibility of polyurethane in a heart valve”. Journal of Applied Polymer Science 98(2), 2005: 758–766.