Miniaturized textile-based multi-layer pH-sensor for wound monitoring applications

• Autorzy: Nocke A. , Schröter A. , Cherif C , Gerlach G.

Identyfikatory

DOI

10.2478/v10304-012-0004-x

• Języki publikacji: EN

Abstrakty

EN

Wound assessment has become an important issue in the wound treatment procedure. One important indicator of the wound status is the pH value. Our approach to assess this quantity is through use of a fiber sensor coated with a pH-responsive hydrogel, which functions as a sensitive layer for impedance measurements. An advantage of this is its integratability into wound dressings using standard textile technologies. The pH characteristic shows a pH-dependent behavior of the absolute impedance at certain frequencies. The fabrication technology and sensor characteristics are discussed. The values of almost 14% impedance change demonstrate the potential for improvement by optimizing fabrication technologies. The presented sensor meets all requirements necessary for wound pH assessment.

Słowa kluczowe

EN

wound monitoring; pH sensor; textile technology; multi-layer fiber

PL

monitorowanie rany; czujnik pH; technologia włókien; włókno wielowarstwowe

• Wydawca: Lodz University of Technology, Faculty of Material Technologies and Textile Design
• Czasopismo: Autex Research Journal
• Rocznik: 2012
• Tom: Vol. 12, no. 1
• Strony: 20--22
• Opis fizyczny: Bibliogr. 14 poz.

Twórcy

autor

Nocke A.

• Institute of Textile Machinery and High Performance Material Technology (ITM), Technische Universität Dresden, Dresden, Germany

autor

Schröter A.

• Solid-State Electronics Laboratory (IFE), Technische Universität Dresden, Dresden, Germany

autor

Cherif C

• Institute of Textile Machinery and High Performance Material Technology (ITM), Technische Universität Dresden, Dresden, Germany

autor

Gerlach G.

• Solid-State Electronics Laboratory (IFE), Technische Universität Dresden, Dresden, Germany

Bibliografia

• 1. Schneider, L.; Korber, A.; Grabbe, S.; Dissemond, J.: Influence of pH on wound-healing: a new perspective for wound-therapy? Archives of Dermatological Research 298(2007)9, pp. 413-420.
• 2. Armstrong, D. G.; Lavery, L. A.; Liswood, O. J.; Todd, W. F.; Tredwell, J. A.: Infrared Dermal Thermometry for the High- Risk Diabetic Foot. Physical Therapy 77(1997)2, pp. 169-175.
• 3. Bharara, M.; Schoess, J.; Nouvong, A.; Armstrong, D. G.: Wound inflammatory index: a “proof of concept” study to assess wound healing trajectory. Journal of Diabetes Science and Technology 4(2010), pp. 773-779.
• 4. Connolly, P.; McColl, D. (18.04.2005): Wound Dressings and Performance Measurement of Such Dressings. US020080171957A1.
• 5. McColl, D.; Cartlidge, B.; Connolly, P.: Real-time monitoring of moisture levels in wound dressings in vitro: An experimental study. International Journal of Surgery 5(2007)5, pp. 316-322.
• 6. Test, S. T.; Weiss, S. J.: Quantitative and temporal characterization of the extracellular H2O2 pool generated by human neutrophils. Journal of Biological Chemistry 259(1984)1, pp. 399-405
• 7. Liu, X.; Zweier, J. L.: A real-time electrochemical technique for measurement of cellular hydrogen peroxide generation and consumption: evaluation in human polymorphonuclear leukocytes. Free Radical Biology and Medicine 31(2001)7, pp. 894-9018.
• 8. Cho, M.; Hunt, T. K.; Hussain, M. Z.: Hydrogen peroxide stimulates macrophage vascular endothelial growth factor release. American Journal of Physiology - Heart and Circulatory Physiology 280(2001)5, pp. H2357-H2363.
• 9. Trabold, O.; Wagner, S.; Wicke, C.; Scheuenstuhl, H.; Hussain, M. Z.; Rosen, N.; Seremetiev, A.; Becker, H. D.; Hunt, T. K.: Lactate and oxygen constitute a fundamental regulatory mechanism in wound healing. Wound Repair and Regeneration 11(2003)6, pp. 504-509.
• 10. Sharp, D.; Davis, J.: Integrated urate sensors for detecting wound infection. Electrochemistry Communications 10(2008) 5, pp. 709-713.
• 11. Sharp, D.; Forsythe, S.; Davis, J.: Carbon fibre composites: integrated electrochemical sensors for wound management. Journal of Biochemistry 144(2008)1, pp. 87-93.
• 12. Vincenzini, P.; Rossi, D. de: Wearable biosensors for monitoring wound healing. Advances in Science and Technology 57(2008), pp. 80-87.
• 13. Schulz, V.; Gerlach, G.; Günther, M.; Magda, J. J.; Solzbacher, F.:. Piezoresistive pH microsensors based on stimulisensitive polyelectrolyte hydrogels. Technisches Messen 77(2010)3, pp. 179-186.
• 14. Richter, A.; Bund, A.; Keller, M.; Arndt, K. - F.: Characterization of a microgravimetric sensor based on pH sensitive hydrogels. Sensors and Actuators B: Chemical 99(2004)2-3, pp. 579-585.