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Influence of thin films of bioglass and hydroxyapatite mixture deposited by PLD method on bioactivity of foam titanium implants

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EN
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EN
The introduction of different bioelements into the structure of hydroxyapatite exerts a positive influence on the growth of new bone tissue. One such useful bioelement is silica, which possesses antibacterial properties and also acts as a factor regulating bone mineralization through stimulation of DNA to synthesize osteoblasts. Results of investigations into integration of foam titanium implants (FTI), with rabbit bone are presented. Two groups of implants were investigated: clean titanium implants produced by selective laser melting and FTI coated with a thin film of hydroxyapatite (HA) mixed with 10 wt. % of bioglass (BG) of A2 type (CaO- P2P-SiO2). Analysis of histopathology of implants' integration with bone were performed by staining using the triple chromatographic method of Masson - Goldner, planimetric analysis using the Kruskal - Wallis test, an ANOVA test and microtomography. Application of layers of the type HA+GH showed superior integration with bone than uncoated titanium implants.
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autor
  • Military University of Technology, Institute of Optoelectronics, Gen.S.Kaliskiego Str., 00-908 Warsaw, Poland
autor
  • Military University of Technology, Institute of Optoelectronics, Gen.S.Kaliskiego Str., 00-908 Warsaw, Poland
  • Military University of Technology, Institute of Optoelectronics, Gen.S.Kaliskiego Str., 00-908 Warsaw, Poland
autor
  • Military University of Technology, Institute of Optoelectronics, Gen.S.Kaliskiego Str., 00-908 Warsaw, Poland
  • Medical University, Department of Orthopaedics, Polish Mother Memorial Hospital, 281/289 Rzgowska Str., 93-338 Lodz, Poland
autor
  • AGH-University of Science and Technology Faculty of Material Science and Ceramics, 30 Mickiewicza Ave, 30-059 Kraków, Poland
  • AGH-University of Science and Technology Faculty of Material Science and Ceramics, 30 Mickiewicza Ave, 30-059 Kraków, Poland
  • AGH-University of Science and Technology Faculty of Material Science and Ceramics, 30 Mickiewicza Ave, 30-059 Kraków, Poland
  • Ghent University, Polymer Chemistry and Biomaterials (PBM) group, Campus Sterre, building S4, Krijgslaan 281, 9000 Gent, Belgium
autor
  • SLM Solutions GmbH, Roggenhorster Strasse 9c, 23556 Lübeck, Germany
Bibliografia
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bwmeta1.element.baztech-c74be03f-1760-40ac-92e6-0905381afe2d
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