Adhesion and growth of cells in culture on carbon-carbon composites with different surface properties

• Autorzy: Bacakova L. , Stary V. , Glogar P.
• Języki publikacji: EN

Abstrakty

EN

The biocompatibility of unidirectionallv reinforced carbon-carbon composites (carbon fibre T300, phenolformaldehyde resin based matrix) with different surface roughness and chemical composition was tested in cell culture conditions. The surface of the composites was polished, covered with amorphous or pyrolytic carbon and seeded with rat aortic smooth muscle cells. Coating with amorphous carbon significantly lowered the number of initially adbered cells. In these samples, the surface roughness had no significant effect on the number of initially adbering cells nor their subsequent proliferation, In contrast, coating with pyrolitic carbon improved significantly both cell adhesion and growth, especially on the polished surfaces. In addition, the layer of pyrolitic carbon was more resistant to mechanical damage than the film of amorphous carbon. It is concluded that polished composites covered by pyrolytic carbon could be suitable for the future application in medicine and biotechnology.

Słowa kluczowe

EN

carbon-carbon composites; biocompatibility; artificial materials

• Wydawca: Polskie Stowarzyszenie Biomateriałów
• Czasopismo: Inżynieria Biomateriałów
• Rocznik: 1998
• Tom: R. 1, nr 2
• Strony: 3--5
• Opis fizyczny: Bibliogr. 18 poz., tab., wykr.

Twórcy

autor

Bacakova L.

• Institute of Physiology, Academy of Sciences of the Czech Republic, Praha, Czech Republic

autor

Stary V.

• Czech Technical University, Faculty of Mechanical Engineering, Dept. of Material Science, Praha, Czech Republic

autor

Glogar P.

• Institute of Rock Structures and Mechanics, Academy of Sciences of the Czech Republic, Praha, Czech Republic