Colloidal quantum dots conjugated with human serum albumin : interactions and bioimaging properties

• Autorzy: Wojnarowska-Nowak R. , Polit J. , Zięba A. , Stolyarchuk I. D. , Nowak S. , Romerowicz-Misielak M. , Sheregii E. M.

Identyfikatory

DOI

10.1016/j.opelre.2017.04.004

• Języki publikacji: EN

Abstrakty

EN

Quantum dots, due to their unique optical properties, constitute significant materials for many areas of nanotechnology and bionanotechnology. This work presents a review of researches dedicated to the interaction between quantum dots (QDs) with human serum albumin (HSA) and human cell culture as important for nanomedicine applications. The optical properties of bio-nanocomplexes formed by nanoparticles including colloidal QDs (e.g., CdTe, CdS, CdCoS) and albumin are displayed. The absorption spectra show that adding HSA to colloidal QDs leads to a gradual decrease of absorption and broadening of the exciton structure. The photoluminescence quenching results indicate that the quenching effect of QDs on HSA fluorescence depends on the size and temperature. The nature of quenching is rather static, resulting in forming QD-HSA complexes. The CdTe QD-HSA complexes show chemical stability in a PBS buffer. Furthermore, it is stable in cytoplasm and suitable for cell labeling, tracking, and other bioimaging applications.

Słowa kluczowe

EN

quantum dot; human serum albumin; interactions; bioimaging properties

• Wydawca: Stowarzyszenie Elektryków Polskich ; Polska Akademia Nauk ; Wojskowa Akademia Techniczna im. Jarosława Dąbrowskiego
• Czasopismo: Opto-Electronics Review
• Rocznik: 2017
• Tom: Vol. 25, No. 2
• Strony: 137--147
• Opis fizyczny: Bibliogr. 84 poz., il., tab., wykr.

Twórcy

autor

Wojnarowska-Nowak R.

• Centre for Microelectronics and Nanotechnology, University of Rzeszow, ul. Pigonia 1, 35-959 Rzeszow, Poland

autor

Polit J.

• Centre for Microelectronics and Nanotechnology, University of Rzeszow, ul. Pigonia 1, 35-959 Rzeszow, Poland

autor

Zięba A.

• Centre for Microelectronics and Nanotechnology, University of Rzeszow, ul. Pigonia 1, 35-959 Rzeszow, Poland

autor

Stolyarchuk I. D.

• Department of Physics of Semiconductors and Nanostructures, Chernivtsi National University, 2 Kotsiubynsky St., 58012 Chernivtsi, Ukraine
• Department of Theoretical and Applied Physics and Computer Simulations, Ivan Franko Drohobych Pedagogical University, 24 I. Franko St., 82100 Drohobych, Ukraine

autor

Nowak S.

• Department of Animal Physiology and Reproduction, Institute of Biotechnology, University of Rzeszow, ul. Werynia 502, 36-100 Kolbuszowa, Poland

autor

Romerowicz-Misielak M.

• Department of Animal Physiology and Reproduction, Institute of Biotechnology, University of Rzeszow, ul. Werynia 502, 36-100 Kolbuszowa, Poland

autor

Sheregii E. M.

• Centre for Microelectronics and Nanotechnology, University of Rzeszow, ul. Pigonia 1, 35-959 Rzeszow, Poland

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Uwagi

EN

This article is an expanded version of the scientific reports presented at theInternational Conference on Semiconductor Nanostructures for Optoelectronics and Biosensors 2016 ICSeNOB2016, May 22–25, 2016, Rzeszow, Poland

PL

Opracowanie ze środków MNiSW w ramach umowy 812/P-DUN/2016 na działalność upowszechniającą naukę (zadania 2017)