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Hemocompatibility of ultrafine systems on the basis of chitosan and its derivatives polymer-colloid complexes

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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
This article presents the results of the development process for the preparation of micro and nano-sized polymer-colloid complexes (РСС) on the basis of water-soluble natural polymer chitosan (СTZ) and the sodium salt of chitosan succinylamid (SСTZ) with silver halide sols in aqueous media. Results of research of СTZ, sodium salt of SСTZ solutions and PСС of CTZ and SСTZ with colloidal particles of silver iodide influence on structurally-functional properties of erythrocytes’ membranes on model of acidic hemolisis are presented in the article. Their influence on the nature of erythrocytes distribution by degree of their stability and on kinetic parameters (the beginning, intensity and completion of process of their destruction) under the influence of the damaging agent (HCl) is shown. The comparative analysis of results convinces that СTZ, SСTZ solutions and disperse systems on the basis of PСС of СTZ and SСTZ with colloidal particles of the silver iodide are capable of modulating variously matrix properties of erythrocytes of blood.
Rocznik
Strony
30--34
Opis fizyczny
Bibliogr. 11 poz., rys., tab.
Twórcy
  • Bashkir State University 32 Zaki Validi Street, 450076 Ufa, Republic of Bashkortostan, Russia
autor
  • Bashkir State University 32 Zaki Validi Street, 450076 Ufa, Republic of Bashkortostan, Russia
  • Bashkir State University 32 Zaki Validi Street, 450076 Ufa, Republic of Bashkortostan, Russia
  • Bashkir State University 32 Zaki Validi Street, 450076 Ufa, Republic of Bashkortostan, Russia
  • Bashkir State University 32 Zaki Validi Street, 450076 Ufa, Republic of Bashkortostan, Russia
  • Institute of Production Enineering, Czestochowa University of Technology, Armii Krajowej 19B, 42-201 Czestochowa, Poland
autor
  • Institute of Biochemical Physics named N.M. Emanuel of Russian Academy of Sciences, Kosygina Street, 119334, Moscow, Russia
Bibliografia
  • 1. Bazunova M.V., Kolesov S.V., Hairullina A.I., Zaikov G.E. Podhod k sozdaniyu lekarstvennyh sredstv prolongirovannogo deistviya na osnove uglerod-polimernyh nositelei. Vestnik Kazanskogo tehnologicheskogo universiteta, 2014, vol.17, № 7, p. 145-147.
  • 2. Bolotova G.V. Polimernye nositeli dlya protivotuberkulyoznyh lekarstvennyh sredstv na osnove hitozana// Molodoi uchenyi, 2010. Vol.2., №5, p. 208-210.
  • 3. Bolotova G.V. Polimernye nositeli dlya protivotuberku-lyoznyh lekartsvennyh sredstv na osnove hitoza-na.//Molodoi uchyonyi, № 5 (16), vol. 2.
  • 4. Eliseeva E.A., E.A. Litmanovich, G.YU. Ostaeva, E.V. Chernikova, I.M. Papisov. Zoli medi, stabilizirovannye polietilenglikol’-600-monolauratom i ego kompleksami s poliakrilovoi kislotoi. Vysokormolekulyarnye soedine-nieya. Seriya A, 2014, vol. 56, № 6, p. 631-637.
  • 5. Inozemceva O.A. Formirovovanie i fiziko-himicheskie svoistva polielektrolitnyh nanokompozitnyh mikrokapsul// Rossiiskie nanotehnologii, 2007, vol.2, № 9, p. 68-80.
  • 6. Kalawnikova I.V, Mehanizmy vzaimodeistviya antibiotikov penicilinovogo ryada s eritrocitami cheloveka//Byull. Eksp biologii i mediciny, 2008, vol. 146, № 10, p.419-423.
  • 7. Korchagina E.V. Agregaciya hitozana i ego proizvodnyh v razbavlennyh vodnyh rastvorah: avtoreferat dissertacii kandidata fiziko-matematicheskih nauk: 02.00.06.: M.: MGU im. M.V. Lomonosova, 2012., p. 232.
  • 8. Lampreht Alf. Nanolekarstva. Koncepcii dostavki lekarstv v nanonauke. M.: Nauchnyi mir, 201, p. 232.
  • 9. Nel A.E., L. Madler, D. Velegol. Understading biophysicochemical interactions at the nan-bio interface// Nature Materials/ 2009. № 8. З. 543-557.
  • 10. Savlukov A.I., V.M. Samsonov, R.F. Kamilov, E.D. Wakirova, R.N. YApparov, D.F. Wakirov. Sostoyanie ustoichivosti eritrocitov kak zveno adaptacii organizma// Medicinskii vestnik Bawkortostana, 2011. vol. 6. №4 p. 13-1.
  • 11. Sevast’yanov V.I., Laksina O.V., Novikova S.P., Rozanova I.B., Ceitlina E.A., Wal’nev B.I. Sovremennye gemosovmestimye materialy dlya serde4no-sosudistoi hirurgii, pod red. V.I. Wumakova, (medicina i zdravoohranenie, seriya hirurgiya, issue 2). M., VNIIMI, 1987.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-c0a0bb80-7043-40d0-9bfa-463a95f3292b
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