Effect of non-modified and modified nanodiamond particles by Fenton reaction on human endothelial cells

• Autorzy: Solarska K. , Gajewska A. , Skolimowski J. , Woś R. , Bartosz G. , Mitura K.
• Języki publikacji: EN

Abstrakty

EN

Purpose: The use of carbon nanoparticles in medicine is increasing due to their high biocompatibility. Nanopowders are one of the best materials which can be used in medicine on medical implants and surgical tools. DPP (Diamond Powder Particles) obtained by different methods which can be expected to affect their properties, including biocompatibility, were compared. The aim of the present study was to compare the biocompatibility of Diamond Powder Particles (DPP) obtained by detonation method and graphite on the basis of their interactions with human endothelial cells. Design/methodology/approach: The effect of nanodiamonds on cell proliferation HUVEC-ST and production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) was studied. We used FT-IR Spectroscopy attributive chemical function groups. Findings: In this subject the material characterization of nanodiamond powders and influence on endothelial cells. Practical implications: Biological research with endothelial cells and nanodiamond powder are the introduction to application in human’s treatment. Originality/value: Nanodiamond powders with chemical modified surface.

Słowa kluczowe

EN

diamond nanoparticles; reactive oxygen species; reactive nitrogen species; biocompatibility

PL

nanocząsteczki diamentu; reaktywne formy tlenu; reaktywne formy azotu; biozgodność

• Wydawca: International OCSCO World Press
• Czasopismo: Journal of Achievements in Materials and Manufacturing Engineering
• Rocznik: 2010
• Tom: Vol. 43, nr 2
• Strony: 603--607
• Opis fizyczny: Bibliogr. 12 poz., wykr.

Twórcy

autor

Solarska K.

• Department of Molecular Biophysics, University of Lodz, ul. Pomorska 141/143, 90-237 Łódź, Poland

autor

Gajewska A.

• Department of Molecular Biophysics, University of Lodz, ul. Pomorska 141/143, 90-237 Łódź, Poland

autor

Skolimowski J.

• Department of Organic Chemistry, University of Lodz, ul. Tamka 12, 91-403 Łódź, Poland

autor

Woś R.

• Division of Biomedical Engineering, Institute of Materials Science and Engineering, Technical University of Lodz, ul. Stefanowskiego 1/15, 90-924 Łódź, Poland

autor

Bartosz G.

• Department of Molecular Biophysics, University of Lodz, ul. Pomorska 141/143, 90-237 Łódź, Poland

autor

Mitura K.

• Division of Biomedical Engineering, Institute of Materials Science and Engineering, Technical University of Lodz, ul. Stefanowskiego 1/15, 90-924 Łódź, Poland
• Koszalin University of Technology, ul. Racawicka 15/17, 75-620 Koszalin, Poland

Bibliografia

• [1] S. Mitura, K. Mitura, P. Niedzielski, P. Louda, V. Danilenko, Nanocrystaline diamond, its synthesis, properties and applications, Journal of Achievements in Materials and Manufacturing Engineering 16 (2006) 9-16.
• [2] J. Grabarczyk, D. Batory, P. Louda, P. Couvrat, I. Kotela, K. Bakowicz-Mitura, Journal of Achievements in Materials and Manufacturing Engineering 20 (2007) 107-110.
• [3] V Yu. Dolmatov, Modern industrial technology of reception detonation nanodiamonds and the basic areas of their use. Nanotechnics 1 (2008) 56-78.
• [4] V.V. Danilenko, Synthesizing and sintering of diamond by explosion, Energoatomizdat, Moscow, 2003 (in Russian).
• [5] A.M. Schrand, S.A. Hens, O.A. Shenderova, Nanodiamond Particles: Properties and Perspectives for Bioapplications Critical Reviews in Solid State and Materials Science 34/1-2 (2009) 18-74.
• [6] R. Martin, P. Concepcion Heydorn, M. Alvaro, H. Garcia, General strategy for high-density covalent functionalization of diamond nanoparticles using fenton chemistry, Chemistry of Materials 21/19 (2009) 4505-4514.
• [7] T. Downs, W. Wilfinger, Fluorometric quantification of DNA in cells and tissue, Analytical Biochemistry 131 (1983) 538-547.
• [8] R. Rago, J. Mitchen, G. Wilding, DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water, Analytical Biochemistry 191 (1990) 31-34.
• [9] J. Grabarczyk, I. Kotela, Plasma modification of medical implants by carbon coatings depositions, Journal of Achievements in Materials and Manufacturing Engineering 37/2 (2009) 277-281.
• [10] K. Mitura, HR TEM examinations for nanodiamond particles for biomedical applications, Journal of Achievements in Materials and Manufacturing Engineering 37/2 (2009) 317-322.
• [11] W. Mark Saltzman, Biomedical Engineering: Bridging Medicine and Technology, Cambridge University Press, United States of America, 2009.
• [12] S. Mitura, Nanodiamonds, Journal of Achievements in Materials and Manufacturing Engineering 24/1 (2007) 166-171.