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Evaluation of personal inhalation exposure to methylene diphenyl diisocyanate (MDI) among 39 employees, working in the window fixation and window glue processes in an automobile manufacturing company was performed. This study was conducted for both case and control groups. After sampling and sample preparation processes, MDI was determined with a UV-VIS spectrophotometer at 590 nm; the lung function was assessed with a digital spirometer, too. The average concentration of MDI in the window fixation, and window glue workplaces were 34.53 and 27.37 μg/m3, respectively, which was lower than the threshold limit value (TLV) recommended by the American Conference of Governmental Industrial Hygienists (ACGIH) (51 μg/m3). Respiratory symptoms in the exposed group were significantly different compared to the unexposed group (p < .05). Lung capacities in the case group were lower than in the control group (p < .05). Therefore, MDI can be easily measured making it possible to evaluate the adverse effects caused by occupational exposure.
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Tom
Strony
443--449
Opis fizyczny
Bibliogr. 22 poz., tab.
Twórcy
autor
- School of Public Health & Institute of Public Health Research Tehran University of Medical Sciences. I.R. Iran
autor
- School of Public Health & Institute of Public Health Research Tehran University of Medical Sciences. I.R. Iran
autor
- School of Public Health & Institute of Public Health Research Tehran University of Medical Sciences. I.R. Iran
Bibliografia
- 1.Lofgren DJ, Walley TL, Peters PM, Weis ML. MDI exposure for spray-on truck bed lining. Appl Occup Environ Hyg. 2003;18:772–9.
- 2.National Institute of Occupational Safety and Health (NIOSH). Criteria for a recommended standard: occupational exposure to toluene diisocynate (NIOSH criteria documents. DHEW [NIOSH] publication No. 73-11022). Cincinnati, OH, USA: NIOSH; 1973.
- 3.National Institute of Occupational Safety and Health (NIOSH). Criteria for a recommended standard: occupational exposure to diisocyanates (NIOSH criteria documents. DHEW [NIOSH] publication No. 78-215). Cincinnati, OH, USA: NIOSH; 1978.
- 4.National Institute of Occupational Safety and Health (NIOSH). Preventing asthma and death from diisocyanate exposure (DHHS [NIOSH] Publication No. 96-111). Cincinnati, OH, USA: NIOSH; 1999.
- 5.BASF Corporation. Polyurethane MDI handbook. Retrieved December 5, 2005, from: http://www.basf.com/urethanechemicals/pdfs/chemicals/Other/2000mdihandbook.pdf
- 6.Crespo J, Galan J. Exposure to MDI during the process of insulating building with sprayed polyurethane foam. Ann Occup Hyg. 1999;43:415–19.
- 7.American Conference of Governmental Industrial Hygienists (ACGIH). Threshold limit values for chemical substances and physical agents. Biological exposure indices. Cincinnati, OH, USA: ACGIH; 2004.
- 8.Petsonk EL, Wang ML, Lewis DM, Siggel PD, Husberg BJ. Asthma-like symptoms in wood product plant workers exposed to methylene diphenyl diisocyanate. Chest. 2000;118:1183–93.
- 9.National Institute of Occupational Safety and Health (NIOSH). Manual of analytical methods (NMAM). Isocyanates, monomeric (DHHS/NIOSH publication No. 94-113). Cincinnati, OH, USA; U.S. Department of Health and Human Services (DHHS); 1994.
- 10.Health and Safety Executive (HSE). Methods for the determination of hazardous substances (MDHS) guidance. Aromatic isocyanates in air (MDHS 49). Sudbury, Suffolk, UK: HSE Books; 1985.
- 11.Health and Safety Executive (HSE). Methods for the determination of hazardous substances (MDHS) guidance. Organic isocyanates in air (MDHS 25/2). Sudbury, Suffolk, UK: HSE Books; 1994.
- 12.Musk AW, Peters JM, DiBerardinis L, Murphy RLH. Absence of respiratory effects in subjects exposed to low concentrations of TDI and MDI. J Occup Med. 1982;24:746–75.
- 13.Littorin M, Truedsson L, Welinder H, Skarping G, Martensson U, Sjoeholm AG. Acute respiratory disorder, rhinoconjunctivitis and fever associated with the pyrolysis of polyurethane derived from diphenylmethane diisocyanate. Scand J Work Environ Health. 1994;20:216–22.
- 14.Streicher R, Reh CM, Key-Schwartz R, Schlecht PC, Cassinelli ME, O’Connor PF. Determination of airborne isocyanate exposure: considerations in method selection. Am Ind Hyg Assoc J. 2000;61:544–56.
- 15.Levine Sp, Hillig KJD, Dharmarajan V, Spence MW, Baker MD. Critical review of methods of sampling, analysis, and monitoring for TDI and MDI. Am Indus Hyg Assoc J. 1995;56:581–9.
- 16.Pham QT, Teculescu D, Meyer-Bisch C, Mur JM. Effects of chronic exposure to diisocyanates. Bull Eur Physiopathol Respir. 1998;23:561–4.
- 17.Sulotto F, Romano C, Piolatto G, Coggiola M, Polizzi S, Ciacco C, Berra A. Short-term respiratory changes in polyurethane foam workers exposed to low MDI concentration. Int Arch Occup Environ Health. 1990;62:521–4.
- 18.Johnson A, Chan-Yeung M, MacLean M. Atkin E, Dybuncio A, Cheng F, et al. Respiratory abnormalities among workers in an iron and steel foundry. Br J Ind Med. 1985;42:94–100.
- 19.Martin FD, Fichet D, Arsanian, G, Leloup MC. Epidemiological study on the toxicity of isocyanates in working environment. Arch Mal Prof. 1982;43:481. In French.
- 20.Akbar-Khanzadeh F. Exposure to particulates and fluorides and respiratory health of workers in an aluminum production potroom with limited control measures. Am Ind Hyg Assoc J. 1995;56:1008–16.
- 21.Golbabaei F, Barghi MA, Sakhaei M. Evaluation of workers’ exposure to total respirable and silica dust and the related health symptoms in Senjedak stome quarry, Iran. Ind Health. 2004;42:29–33.
- 22.Alizadeh A, Nasl Seraji J, Kakooei H. Evaluation of lung capacity in coal mine worker in Mazandaran Province, Iran. Journal of Shahid Sadoughi University of Medical Sciences and Health Services. 2001;8:58–63.
Typ dokumentu
Bibliografia
Identyfikator YADDA
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