Promieniowanie UV jako kluczowy czynnik w prebiotycznej syntezie i selekcji komponentów kwasów nukleinowych

• Autorzy: Szabla Rafał

Identyfikatory

DOI

10.53584/WIADCHEM.2025.11.3

Warianty tytułu

EN

UV radiation as the key factor in prebiotic synthesis and selection of nucleic acid components

• Języki publikacji: PL

Abstrakty

EN

Understanding the origins of biomolecules on Earth and discovering plausible reaction pathways that lead to their formation has been a notorious challenge for chemists. In particular, the origins of functional RNA fragments still remain largely obscure. Recent discoveries in this field proposed credible scenarios for the synthesis of nucleosides and nucleotides, demonstrating the crucial role of UV irradiation in promoting selective photochemical transformations and degrading biologically irrelevant components of the so-called prebiotic soup. In this work, I discuss the role of computational chemistry in these discoveries and underscore the importance of investigating prebiotic photochemistry at all stages of prebiotic molecular assembly, starting from small-molecule nucleic acid precursors up to RNA and DNA oligomers. The insights obtained from quantum chemical simulations of possible reaction paths can elucidate the mechanisms of non-intuitive reactions and offer predictive capacity for experiments aiming to discover similar or analogous reactions in related systems.

Słowa kluczowe

PL

fotochemia; chemia prebiotyczna; promieniowanie UV

EN

photochemistry; prebiotic chemistry; UV radiation

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Wiadomości Chemiczne
• Rocznik: 2025
• Tom: [Z] 79, 11-12
• Strony: 923--942
• Opis fizyczny: Bibliogr. 48 poz., rys., wykr.

Twórcy

autor

Szabla Rafał

• Instytut Materiałów Zaawansowanych, Wydział Chemiczny, Politechnika Wrocławska, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław

• https://orcid.org/0000-0002-1668-8044

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