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The study on pH gradient control in solution for driving bacteria

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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Medical applications are the most impactful areas of microrobotics, such as targeting tumoral lesions for therapeutic purposes, minimally invasive surgery (MIS) and highly localized drug delivery. However, miniaturization of the power source with an effective on board controllable propulsion system has prevented the implementation of such mobile robots. Flagellated chemotactic bacteria can be used as an effective integrated propulsion system for microrobots. In this paper, we study the pH gradients control in solution for driving bacteria. The swimming property of flagellar bacteria and mechanism of forming the pH gradient field in solution are discussed. By experiments, we found that the pH gradient field distribution in solution is mainly related to the electrode shape. And the input voltage value can control the stable time of the pH gradient field, while it has no effect on the distribution of the field. The electric potential distribution is analyzed by simulation with COMSOL Multiphysics. The simulation results are consistent with the experiment results, which indicate that the bacteria movement can be controlled by the electrodes' shape and the input voltage.
Twórcy
autor
  • Department of Control Science & Engineering, Tongji University, Shanghai, China
autor
  • Department of Control Science & Engineering, Tongji University, Shanghai, China
autor
  • Department of Control Science & Engineering, Tongji University, Shanghai, China
autor
  • Department of Control Science & Engineering, Tongji University, Shanghai, China
autor
  • College of Computer Science, Hangzhou Dianzi University, Hangzhou, China
Bibliografia
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  • [3] Edd J, Payen S, Rubinsky B, Stoller ML, Sitti M. Biomimetic propulsion for a swimming surgical micro-robot. In: Proc IEEE/RSJ Int Conf Intell Robots Syst; 2003. pp. 2583–8.
  • [4] Bell DJ, Leutenegger S, Hammar KM, Dong LX, Nelson BJ. Flagella-like propulsion for microrobots using a nanocoil and a rotating electromagnetic field. In: Proc IEEE Int Conf Robot Autom; 2007. pp. 1128–33.
  • [5] Martel S, Mohammadi M, Felfoul O, Lu Z, Poupanneau P. Flagellated magnetotactic bacteria as controlled MRI-trackable propulsion and steering systems for medical nanorobots operating in the human microvasculature. Int J Robot Res 2009; 28: 571–82.
  • [6] Julius AA, Sakar MS, Steager E, Cheang UK, Kim MJ, Kumar V, Pappas GJ. Harnessing bacterial powerin microscale actuation. In: Proc IEEE Int Conf Robot Autom; 2009. pp. 1004–9.
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  • [12] Behkamand B, Sitti M. Effect of quantity and configuration of attached bacteria on bacterial propulsion of microbeads. Appl Phys Lett 2008; 93: 1–3. 223901.
  • [13] Martel S, Tremblay CC, Ngakeng S, Langlois G. Controlled manipulation and actuation of micro-objects with magnetotactic Bacteria. Appl Phys Lett 2006; 89:1–4. 233904.
  • [14] Aranson IS, Sokolov A, Kessler JO, Goldstein RE. Model for dynamical coherence in thin films of self-propelled microorganisms. Phys Rev E 2007; 75: 1–4. 040901.
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  • [17] Sokolov A, Aranson IS, Kessler JO, Goldstein RE. Concentration dependence of the collective dynamics of swimming bacteria. Phys Rev Lett 2007; 98: 1–4. 158102.
  • [18] Samatey FA, Imada K, Nagashima S, Vonderviszt F, Kumasaka T, Yamamoto M, Namba K. Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling. Nature 2001; 410: 331–7.
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Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-b85e7260-dadc-4a6f-aa03-7fcb2f501090
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