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Nanoemulsions based on selected berry seed oils

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PL
Nanoemulsje na bazie wybranych olejów z nasion owoców jagodowych
Języki publikacji
EN
Abstrakty
EN
The aim of this work was the preparation of O/W nanoemulsions based on supercritical CO2 extracted (SC-CO2) oils from seeds of strawberry and blackcurrant. The emulsion systems were obtained by the phase inversion composition method, at T = 25°C. Polysorbate 80 and Natragem S150 were used as the surfactant and co-surfactant, respectively. Kinetic stability of the prepared formulations with varying surfactant: oil (S:O) and surfactant/co-surfactant (S/CoS) weight ratio, was analysed by measuring the droplet size (DLS method) in time. The obtained results show that a nanoemulsion based on blackcurrant seed oil was characterised by the smallest droplet size (r = 15 nm), a low polydispersity index (PDI = 0.246) and the longest kinetic stability (S:CoS = 8:2, S/CoS:O = 9:1).
PL
Celem pracy było otrzymanie nanoemulsji O/W, w których rolę fazy olejowej pełnił ekstrakt z nasion truskawki lub czarnej porzeczki otrzymany w warunkach nadkrytycznego CO2 (SC-CO2). Układy emulsyjne otrzymano metodą składnikowej inwersji faz, w T = 25°C. Jako surfaktant zastosowano Polisorbat 80, rolę kosurfaktantu pełnił Natragem S150. Kinetyczną stabilność otrzymanych formulacji badano poprzez pomiar wielkości cząstek nanoemulsji (technika DLS) w czasie, dla układów o różnym stosunku wagowym surfaktant: olej (S:O) oraz surfactant/kosurfaktant (S/CoS). Otrzymane rezultaty wykazały, że najmniejszym rozmiarem cząstek fazy wewnętrznej (r = 15 nm), niskim indeksem polidyspersyjności (PDI = 0.246) oraz najdłuższą kinetyczną stabilnością charakteryzowała się nanoemulsja na bazie oleju z nasion czarnej porzeczki (S:CoS = 8:2, S/CoS:O = 9:1).
Rocznik
Strony
91--100
Opis fizyczny
Bibliogr. 28 poz., tab., wykr.
Twórcy
  • Institute of Inorganic Chemistry and Technology, Faculty of Chemical Engineering and Technology, Cracow University of Technology
autor
  • Institute of Inorganic Chemistry and Technology, Faculty of Chemical Engineering and Technology, Cracow University of Technology
autor
  • Institute of Inorganic Chemistry and Technology, Faculty of Chemical Engineering and Technology, Cracow University of Technology
Bibliografia
  • [1] Malinowska O., Szeląg H., The investigation of application possibilities and rheological behavior of crude fruit seed oil in emulsion system, International Journal of Research in Cosmetic Science, Vol. 3(1), 2013, 7–13.
  • [2] Jaworska M., Sikora E., Ogonowski J., Nanoemulsje – charakterystyka i metody otrzymywania, Przemysł Chemiczny, Vol. 93(7), 2014, 1000–1005.
  • [3] Sharma A., Kumar. S.M, Mahadevan N., Nanotechnology: A Promising Approach For Cosmetics, International Journal of Recent Advances in Pharmaceutical Research, Vol. 2(2), 2012, 54–61.
  • [4] Fernandez P., Andre V., Rieger J., Kühnle A., Nano–emulsion formation by emulsion phase inversion,Colloids and Surfaces A: Physicochem. Eng. Aspects, Vol. 251, 2004, 53–58.
  • [5] Porras M., Solans C., Gonzalez C., Gutierrez J.M., Properties of water–in–oil (W/O) nano–emulsions prepared by a low–energy emulsification method, Colloids and Surfaces A:Physicochem.Eng.Aspects, Vol. 324, 2008, 181–188.
  • [6] Tadros T., Izquierdo P., Esquena J., Solans C., Formation and stability of nano–emulsions, Advances in Colloid and Interface Science, Vol. 108–109, 2004, 303–318.
  • [7] Yang H., Cho W., Park S., Stability of oil–in–water nano–emulsions prepared using the phase inversion composition method, Journal of Industrial and Engineering Chemistry, Vol. 15, 2009, 331–335.
  • [8] Usón N., Garcia M.J., Solans C., Formation of water–in–oil (W/O) nanoemulsions in a water/mixed nonionic surfactant/oil systems prepared by low energy methods, Colloids and Surfaces A:Physicochem.Eng.Aspects, Vol. 250, 2004, 415–421.
  • [9] Sadurni N., Solans C., Azemar N., Garcia–Celma M.J., Studies on the formation of O/W nano–emulsions, by low–energy emulsification methods, suitable for pharmaceutical applications, European Journal of Pharmaceutical Sciences Vol. 26, 2005, 438–445.
  • [10] Kelmann R., Kuminek G., Teixeira H., Koester L., Carbamazepine parenteral nanoemulsions prepared by spontaneous emulsification process, International Journal of Pharmaceutics, Vol. 342, 2007, 231–239.
  • [11] Saberi A., Fang Y., McClements F.D., Fabrication of vitamin E–enriched nanoemulsions: Factors affecting particle size using spontaneous emulsification, Journal of Colloid and Interface Science, Vol. 391, 2013, 95–102.
  • [12] Alayoubi A.Y., Anderson J.F., Satyanarayanajois S.D., Sylvester P.W., Nazzal S., Concurrent delivery of tocotrienols and simvastatin by lipid nanoemulsions potentiates their antitumor activity against human mammary adenocarcenoma cells, European Journal of Pharmaceutical Sciences, Vol.48(3), 2013, 385–392.
  • [13] Araujo F.A., Kelmann B.V., Araujo B.V., Finatto R.B., Teixeira H.F., Koester L.S., Development and characterization of parenteral nanoemulsions containing thalidomide, European Journal of Pharmaceutical Science, Vol. 42(3), 2011, 238–245.
  • [14] Kuo F., Subramanian B., Kotyla T., Wilson T., Yoganathanb S., Nicolosi R., Nanoemulsions of an antioxidant synergy formulation containing tocopherol have enhanced bioavailability and anti –inflammatory properties, International Journal of Pharmaceutics, Vol. 363, 2008, 206–213.
  • [15] Mou D., Chen H., Du D., Mao C., Wan J., Xu H., Yang X., Hydrogel –thickened nanoemulsion system for topical delivery of lipophilic drugs, International Journal of Pharmaceutics International Journal of Pharmaceutics, 2008, 353, 270–276.
  • [16] Kotyla T., Kuo F., Moolchandani V., Wilson T., Nicolosi R., Increased bioavailability of a transdermal application of a nano–sized emulsion preparation, International Journal of Pharmaceutics, Vol. 347, 2008, 144–148.
  • [17] Bernardi D., Pereira T., Maciel N., Bortoloto J., Viera G., Oliveira G., Rocha–FilhoP., Formation and stability of oil–in–water nanoemulsions containing rice bran oil: in vitro and in vivo assessments, Journal of nanobiotechnology, 2011, 9–44.
  • [18] Davidov-Pardo G., McClements D.J., Nutraceutical delivery systems: Resveratrol encapsulation in grape seed oil nanoemulsions formed by spontaneous emulsification, Food Chemistry, Vol. 167, 2015, 205–2012.
  • [19] Eid A.M.M., Baie S.H., Arafat O.M., The Effect of Surfactant Blends on the Production of SelfEmulsifying System, Vol. 2(2), 2012, 21–31.
  • [20] Dweck A.C., Formulating Natural Cosmetics, Allured Books, 2011 .
  • [21] Hoed V., De Clercq N., Echim C., Andjelkovic M., Leber E., Dewettinck K., Verhé R., Berry seeds: a source of specialty oils with high content of bioactives and nutritionalvalue, Journal of Food Lipids, Vol. 16, 2009, 33–49.
  • [22] Sikora E., Michorczyk P., Olszańska M., Ogonowski J., Supercritical CO2 extract from strawberry seeds as a valuable, component of mild cleansing compositions, International Journal of Cosmetic Science, Vol. 37, 2015, 574–578.
  • [23] Rój E., Dobrzyńska-Inger A., Kostrzewa D., Kołodziejczyk K., Sój M., Król B., Miszcza A., Markowski J., Extraction of berry seed oils with supercritical CO2, Przemysł Chemiczny, Vol. 88 (12), 2009, 1325–1330.
  • [24] Sovilj M., Critical review of supercritical carbon dioxide extraction of selected oil seeds, APTEFF, Vol. 41, 2010, 105–120.
  • [25] Ostertag F., Weiss J., McClements D.J., Low–energy formation of edible nanoemulsions: Factors influencing droplet size produced by emulsion phase inversion, Journal of Colloid and Interface Science, Vol. 388, 2012, 95–102.
  • [26] Li Y., Zhang Z., Yuan Q., Liang H., Vriesekoop F., Process optimization and stability of D–limonene nanoemulsions preapred by catastrophic phase inversion method, Journal of Food Engineering, Vol. 119, 2013, 419–424.
  • [27] Komaiko J., McClements D.J., Low–energy formation of edible nanoemulsions by spontaneous emulsification: Factors influencing particle size, Journal of Foofdc Engineering, Vol. 146, 2015, 122–128.
  • [28] Anton N., Vandamme T., The universality of low–energy nano–emulsification, International Journal of Pharmaceutics, Vol. 377, 2009, 142–147.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-b67a585d-096f-4426-ad30-97bc92027cd3
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