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Easy, Simplistic and Green Synthesis of Various Benzimidazole and Benzoxazole Derivatives Using PEG400 as a Green Solvent

Treść / Zawartość
Identyfikatory
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
An improved environmentally benign procedure for the synthesis of various benzimidazole and benzoxazole derivatives using green solvent PEG400. We have optimized the reaction condition and it was found that PEG400 was believed to be best as compared to PEG200, PEG600 and PEG800 at 80 to 85 °C. This method provides a novel route for the synthesis of benzimidazole and benzoxazole derivatives. The main attractive features of this process are a mild reaction conditions, easy workup procedure and good to excellent yield. The structures of all the synthesized compounds were confirmed by 1H NMR, IR, MASS and Elemental Analysis.
Słowa kluczowe
Rocznik
Tom
Strony
61--68
Opis fizyczny
Bibliogr. 18 poz., tab., wz.
Twórcy
autor
  • Department of Chemistry, Saurashtra University, Rajkot-360005, Gujrat, India
  • Department of Chemistry, Saurashtra University, Rajkot-360005, Gujrat, India
  • Department of Chemistry, Saurashtra University, Rajkot-360005, Gujrat, India
autor
  • Department of Chemistry, Saurashtra University, Rajkot-360005, Gujrat, India
autor
  • Department of Chemistry, Saurashtra University, Rajkot-360005, Gujrat, India
Bibliografia
  • [1] (a) N. Candeias, L. Branco, P. Gois, C. Afonso, A. Trindade, Chem. Rev. 109 (2009) 2703-2802; (b) M. Martins, C. Frizzo, D. Moreira, L. Buriol, P. Machado, Chem. Rev. 109 (2009) 4140-4182; (c) P. Walsh, H. Li, C. Parrodi, Chem. Rev. 107 (2007) 2503-2545.
  • [2] F. Bailey, J. Koleske, Poly(ethylene oxide); Academic: NY, New York, (1976) 173.
  • [3] E. Colacino, L. Daı¨ch, J. Martinez, F. Lamaty, Synthetic letter (2007) 1279-1283.
  • [4] V. Declerck, J. Martinez, F. Lamaty, Synthetic letter (2006) 3029-3032.
  • [5] V. Declerck, P. Ribie` re, Y. Ne´ dellec, H.Allouchi, J. Martinez, F. Lamaty, European Journal Organic Chemistry (2007) 201-208.
  • [6] P. Ribie` re, V. Declerck, Y. Ne´ dellec, Y. Bhatnagar, J. Martinez, F. Lamaty, Tetrahedron 62 (2006) 10456-10466.
  • [7] P. Ribie` re, C. Enjalbal, J. Aubagnac, Y. Bhatnagar, J. Martinez, F. Lamaty, Journal of combinatorial chemistry 6 (2004) 464-467.
  • [8] P. Ribie` re, Y. Bhatnagar, J. Martinez, F. Lamaty, QSAR combinatorial science 23 (2004) 911-914.
  • [9] D. Evans, C. Sacks, W. Kleschick, T. Taber, Journal of American Chemical Society 101 (1979) 6789-6791.
  • [10] X. Song, B. Vig, P. Lorenzi, J. Drach, L. Townsend, G. Amidon, Journal of Medicinal Chemistry 48 (2005) 1274-1277.
  • [11] M. Yamato, Journal of Pharmaceutical Society of Japan 112 (1992) 81-99.
  • [12] I. Yildiz-Oren, I. Yalcin, E. Aki-Sener, N. Ucarturk, European Journal of Medicinal Chemistry 39 (2004) 291-298.
  • [13] D. Kumar, M. Jacob, M. Reynolds, S. Kerwin, Bioorganic Medicinal Chemistry 10 (2002) 3997-4004.
  • [14] B. L. Mylari, E. Larson, T. Beyer, W. Zembrowski, C. Aldinger, M. Dee, T. Siegel, D. Singleton, Journal of Medicinal Chemistry 34 (1991) 108-122.
  • [15] (a) K. Nagata, T. Itoh, H. Ishikawa, A. Ohsawa, Heterocycles 61 (2003) 93-96; (b) M. Curini, F. Epifano, F. Montanari, O. Rosati, S. Taccone, Synthetic Letter 10 (2004) 1832-1834; (c) M. Chakrabarty, S. Karmakar, M. Ajanta, S. Arima, Y. Harigaya, Heterocycles 68 (2006) 967-974; (d) H. Aliyan, R. Fazaeli, N. Fazaeli, A. Mssah, H. Naghash, M. Alizadeh, G. Emami, Heteroatom Chemistry 20 (2009) 202-207.
  • [16] (a) R. Kumar, C. Selvam, G. Kaur, A. Chakraborti, Synthetic letter 09 (2005) 1401-1404; (b) J. Seijas, M. Vázquez-Tato, M. Carballido-Reboredo, J. Crecente-Campo, L. Romar-López, Synthetic Letter (2007) 313-316.
  • [17] H. Bachhav, S. Bhagat, V. Telvekar, Tetrahedron Letters 52 (2011) 5697-5701.
  • [18] G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 5 (2014) 89-98.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-b506c12d-44e3-404d-9747-2de5526610b4
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