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Abstrakty
The rate of oxygen transport from atmospheric air into water and perfluorocarbon compound (PFC) was investigated. Static and dynamic systems with and without the presence of the lung surfactant monolayer were considered. For the case of water used as an oxygen absorbent, the monolayer activity allowed a simulation of the gas uptake into the lung hypophase. In the second case, a two-phase liquid system with water as a hypophase and PFC as the blood substitute simulated oxygen transport in the alveolus-blood system. Original experimental measurement devices gave the opportunity of determining the gas transport rate with the possibilities of indicating the role of the lung surfactant in the process and evaluating the influence of environmental conditions on the transport phenomena. Results of that work suggest a possible enhancing role of the lung surfactant in the oxygen transfer rate.
Wydawca
Rocznik
Tom
Strony
391--409
Opis fizyczny
Bibliogr. 16 poz., rys., tab., wykr.
Twórcy
autor
- Warsaw University of Technology, Poland
autor
- Warsaw University of Technology, Poland
autor
- Warsaw University of Technology, Poland
autor
- Warsaw University of Technology, Poland
Bibliografia
- 1.Akino, T. (1992). Lipid components of the surfactant system. In B. Robertson, L.M.G. Van Golde, & J.J. Batenburg (Eds.), Pulmonary surfactant: From molecular biology to clinical practice (pp. 19-31). Amsterdam: Elsevier Science.
- 2.Blank, M., & Roughton, F.J.W. (1960). The permeability of monolayers to carbon dioxide. Transactions o f the Faraday Society, 56, 1832-1841.
- 3.Gaines, G.L., Jr. (1966). Insoluble monolayers at liquid-gas interfaces. New York: Interscience.
- 4.Gehr, P., Green, F.H.Y., Geiser, M., Im Hof, V., Lee, M.M ., & Schiirch, S. (1996). Airway surfactant, a primary defense barrier: Mechanical and immunological aspects. Journal of Aerosol Medicine, 9, 163-181.
- 5.Gradon, L., & Podgorski, A. (1995). Displacement of alveolar macrophages in the air space o f human lung. Medical and Biological Engineering and Computing, 33, 575-581.
- 6.Gradon, L., Podgorski, A., & Sosnowski, T.R. (1996). Experimental and theoretical investigation of transport properties of DPPC monolayer. Journal o f Aerosol Medicine, 9, 357-367.
- 7.Keough, K.M.W. (1992). Physical chemistry of pulmonary surfactant in the terminal air spaces. In B. Robertson, L.M.G. Van Golde, & JJ. Batenburg (Eds.), Pulmonary surfactant: From molecular biology to clinical practice (pp. 109-164). Amsterdam: Elsevier Science.
- 8.Notter, R.H., & Finkelstein, J.N. (1984). Pulmonary surfactant: An interdisciplinary approach. Journal o f Applied Physiology, 57, 1613-1624.
- 9.Notter, R.H., Taubold, R., & Mavis, R.D. (1982). Hysteresis in saturated phospholipid films and its potential relevance for lung surfactant functions in vivo. Experimental Lung Research, 3, 109-127.
- 10.Podgorski, A., & Gradon, L. (1993). An improved mathematical model of hydrodynamical self-cleansing of pulmonary alveoli. Annals of Occupational Hygiene, 37, 347-365.
- 11.Sosnowski, T.R. (1997). Hydrodynamic and surface phenomena in the lung surfactant system. Warsaw, Poland: Warsaw University of Technology. (In Polish).
- 12.Sosnowski, T.R., & Gradon, L. (1993). Influence of ozone contained in the air on respiratory functions. In vitro study. Postępy Aerozoloterapii, 1, 77-92. (In Polish).
- 13.Sosnowski, T.R., & Gradon, L. (1995). Influence of toxic gases on alveolar surface transport. Journal o f Aerosol Medicine, 8, 113.
- 14.Sosnowski, T.R., & Gradon, L. (1997). Influence of acid fogs on lung surfactant function. Journal o f Aerosol Medicine, 10, 279.
- 15.Van Iwaarden, J.F. (1992). Surfactant and the pulmonary defense system. In B. Robertson, L.M.G. Van Golde, & J.J. Batenburg (Eds), Pulmonary surfactant: From molecular biology to clinical practice (pp. 215-227). Amsterdam: Elsevier Science.
- 16.Wesseler, E.P., litis, R., & Clark, L.J. (1977). The solubility of oxygen in highly fluorinated liquids. Journal of Fluorine Chemistry, 9, 137-146.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-b4262f89-aef8-4e96-9432-8f3b027724c2