The layer-specific biomechanical properties of dissecting ascending aortic aneurysm (Stanford type A of dissection)

• Autorzy: Kozuń Marta , Kaczorowski Maciej , Haloń Agnieszka

Identyfikatory

DOI

10.37190/ABB-02020-2022-01

• Języki publikacji: EN

Abstrakty

EN

The aims of this paper was the analysis of the mechanical properties of dissected wall of the ascending aortic aneurysm (n = 12). Methods: All aortas were collected from men (mean age: 48 ± 12 years, mean diameter of the aneurysm: 49 mm ± 4 mm). The mechanical properties were determined based on directional tensile test. The biomechanical assay was complemented by conducting histological analysis (hematoxylin and eosin, Mallory’s trichrome, Azan stain). Results: The highest values (median) of failure Cauchy stress, failure force, Young’s modulus and stiffness coefficient were obtained for the adventitia (max = 1.40 MPa, Fmax = 4.05 N, E = 26.11 MPa, k = 1.06 N/mm). Conclusions: The results indicate that the mechanical function of the adventitia in healthy tissue and dissected ascending aorta aneurysm is the same, i.e., it protects the vessel against destruction. The failure Cauchy stresses found in the media and intima are comparable and amounted to 0.23 and 0.21 MPa, respectively. The results indicate that dissection affects the mechanical properties of ascending aorta wall layers. The mechanical loads are probably transferred within the dissected aneurysmal wall not only through the media, but also through the intima.

Słowa kluczowe

EN

dissection; mechanical properties; human ascending aorta; aneurysm; dissecting aneurysm; aorta layers

• Wydawca: Oficyna Wydawnicza Politechniki Wrocławskiej
• Czasopismo: Acta of Bioengineering and Biomechanics
• Rocznik: 2022
• Tom: Vol. 24, no. 2
• Strony: 3--14
• Opis fizyczny: Bibliogr. 31 poz., rys., tab., wykr.

Twórcy

autor

Kozuń Marta

• Department of Mechanics, Materials and Biomedical Engineering, Wrocław University of Science and Technology, Wrocław, Poland.

autor

Kaczorowski Maciej

• Department of Pathomorphology and Oncological Cytology, Wroclaw Medical University, Wrocław, Poland.

autor

Haloń Agnieszka

• Department of Pathomorphology and Oncological Cytology, Wroclaw Medical University, Wrocław, Poland.

Bibliografia

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