Cardiometabolic risk prediction in patients with non-alcoholic fatty liver disease combined with subclinical hypothyroidism

• Autorzy: Kolesnikova Olena , Vуsotska Olena , Potapenko Anna , Radchenko Anastasia , Trunova Anna I. , Virstyuk Nataliya , Vasylevska-Skupa Liudmyla , Kalizhanova Aliya , Mukanova Nazerka

Identyfikatory

DOI

10.35784/iapgos.3654

Warianty tytułu

PL

Przewidywanie ryzyka kardiometabolicznego u pacjentów z niealkoholową stłuszczeniową chorobą wątroby w połączeniu z subkliniczną niedoczynnością tarczycy

• Języki publikacji: EN

Abstrakty

EN

One of the most common diseases of our time is non-alcoholic fatty liver disease (NAFLD). Recently published research results indicate that patients with NAFLD along with traditional risk factors for cardiovascular diseases (CVD) have "new"risk factors such as endothelial dysfunction (ED), carotid intima-media thickness (CIMT), an increase in the CRP level, as well as risk factors combined into the Framingham scale. It is also knownthat combination of NAFLD with subclinical hypothyroidism (SH) forms an abnormal metabolic phenotype, which is associated with cardiometabolicrisk factors. The study of cardiometabolic predictors and vascular markers in patients with NAFLD in combination with SH willprovide an opportunityto improve the strategy of cardiovascular events prevention in such comorbid patients.

PL

Niealkoholowe stłuszczenie wątroby (NAFLD) jest jedną z najczęstszych chorób naszych czasów. Ostatnio opublikowane wyniki badań sugerują, że pacjenci z NAFLD, wraz z tradycyjnymi czynnikami ryzyka chorób sercowo-naczyniowych (CVD), mają "nowe" czynniki ryzyka, takie jak dysfunkcja śródbłonka (ED), grubość błony wewnętrznej i środkowej tętnicy szyjnej (CIMT), podwyższony poziom CRP i czynniki ryzyka połączone w skali Framingham. Wiadomo również, że połączenie NAFLD z subkliniczną niedoczynnością tarczycy (SH) tworzy nieprawidłowy fenotyp metaboliczny związany z czynnikami ryzyka kardiometabolicznego. Badanie predyktorów kardiometabolicznych i markerów naczyniowych u pacjentów z NAFLDw połączeniu z SH pozwoli na ulepszenie strategii zapobiegania zdarzeniom sercowo-naczyniowym u takich współistniejących pacjentów.

Słowa kluczowe

EN

cardiometabolic risk; non-alcoholic fatty liver disease; subclinical hypothyroidism; prediction; binary regression logistic analysis; validation of prognostic models

PL

ryzyko kardiometaboliczne; niealkoholowe stłuszczenie wątroby; subkliniczna niedoczynność tarczycy; rokowanie; binarna analiza regresji logistycznej; walidacja modeli prognostycznych

• Wydawca: Wydawnictwo Politechniki Lubelskiej
• Czasopismo: Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
• Rocznik: 2023
• Tom: T. 13, nr 2
• Strony: 64--68
• Opis fizyczny: Bibliogr. 20 poz., tab., wykr.

Twórcy

autor

Kolesnikova Olena

• Government Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine

• https://orcid.org/0000-0001-5606-6621

autor

Vуsotska Olena

• National AerospaceUniversity"Kharkiv Aviation Institute", Kharkiv, Ukraine, 3Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine

• https://orcid.org/0000-0003-3723-9771

autor

Potapenko Anna

• Government Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine

• https://orcid.org/0000-0002-1658-0156

autor

Radchenko Anastasia

• Government Institution "L. T. Malaya Therapy Institute of the National Academy of Medical Science of Ukraine", Kharkiv, Ukraine

• https://orcid.org/0000-0002-9687-8218

autor

Trunova Anna I.

• National AerospaceUniversity"Kharkiv Aviation Institute", Kharkiv, Ukraine, 3Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine

• https://orcid.org/0000-0001-7069-0674

autor

Virstyuk Nataliya

• Vinnytsia Mychailo Kotsiubynskyi State Pedagogical University, Vinnytsia,Ukraine

• https://orcid.org/0000-0002-5794-8754

autor

Vasylevska-Skupa Liudmyla

• Vinnytsia Mychailo Kotsiubynskyi State Pedagogical University, Vinnytsia,Ukraine

• https://orcid.org/0000-0002-1989-7175

autor

Kalizhanova Aliya

• Institute of Information and Computational Technologies, Almaty, Kazakhstan

• https://orcid.org/0000-0002-5979-9756

autor

Mukanova Nazerka

• Gymnasium No. 159 named after Y. Altynsarin, Almaty, Kazakhstan

• https://orcid.org/0009-0002-7945-7187

Bibliografia

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2024).