Mathematical modelling of UK rubella vaccination programs

• Autorzy: Greenhalgh D. , Sfikas N.
• Języki publikacji: EN

Abstrakty

EN

In this article we discuss mathematical modelling of vaccination programs for rubella in the UK. We briefly discuss rubella before outlining the underlying mathematical model. Age-structured serological data is used to estimate the force of infection in the absence of vaccination and hence the mixing matrix. Homogeneous, proportional and symmetric mixing are considered. The estimated mixing matrix is used to evaluate the basic reproduction number R0 and minimum elimination vaccination programs using one stage and two stage vaccination strategies.

Słowa kluczowe

EN

Rubella; age structure; serological profile; R0; vaccination

PL

różyczka; struktura wiekowa; serologiczny profil; szczepienia

• Wydawca: University of Silesia, Institute of Informatics, Computer Systems Department
• Czasopismo: Journal of Medical Informatics & Technologies
• Rocznik: 2002
• Tom: Vol. 3
• Strony: MI3--11
• Opis fizyczny: Bibliogr. 11 poz., rys., tab.

Twórcy

autor

Greenhalgh D.

• Department of Statistics and Modelling Science, University of Strathclyde, Livingstone Tower, 26 Richmond Street, Glasgow G1 1XH, U.K.

autor

Sfikas N.

• Novartis Pharma AG, Basel, Switzerland

Bibliografia

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