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Feature selection for breast cancer malignancy classification problem

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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The paper provides a preview of some work in progress on the computer system to support breast cancer diagnosis. Diagnosis approach is based on microscope images of the FNB (Fine Needle Biopsy) and assumes distinguishing malignant from benign cases. Studies conducted focus on two different problems, the first concern the extraction of morphometric parameters of nuclei present in cytological images and the other concentrate on breast cancer nature classification using selected features. Studies in both areas are conducted in parallel. This work is devoted to the problem of feature selection from the set of determined features in order to maximize the accuracy of classification. Morphometric features are derived directly from a digital scans of breast fine needle biopsy slides and are computed for segmented nuclei. The quality of feature space is measured with four different classification methods. In order to illustrate the effectiveness of the approach, the automatic system of malignancy classification was applied on a set of medical images with promising results.
Rocznik
Tom
Strony
193--199
Opis fizyczny
Bibliogr. 19 poz., rys., tab.
Twórcy
autor
  • University of Zielona Góra, Institute of Control and Computation Engineering
autor
autor
Bibliografia
  • [1] BREIMAN L., FRIEDMAN J., STONE C.J., OLSHEN R.A., Classification and Regression Trees, Chapman & Hall, Boca Raton, 1993.
  • [2] HREBIEŃ M., STEĆ P., OBUCHOWICZ A., NIECZKOWSKI T., Segmentation of breast cancer fine needle biopsy cytological images. Int. J. Appl. Math and Comp. Sci. Vol. 18, No. 2, 2008, pp. 159–170.
  • [3] HUANG H.K., PACS and Imaging Informatics: Basic Principles and Applications, John Wiley & Son, New Jersey, 2010.
  • [4] JELEŃ Ł., FEVENS T., KRZYŻAK A., Classification of breast cancer malignancy using cytological images of fine needle aspiration biopsies, Int. J. Appl. Math and Comp. Sci. Vol. 18, No. 1, 2008, pp. 75–83.
  • [5] JELEŃ Ł., FEVENS T., KRZYŻAK A., JELEŃ M., Discriminatory Power of Cells Grouping Features for Breast Cancer Malignancy Classification, Proc. 4th Int. Conf. on Biomedical Engineering, Kuala Lumpur, 2008, pp. 559–562.
  • [6] KAWA J., PIĘTKA E., Image Clustering with Median and Myriad Spatial Constraint Enhanced FCM, Proc. 4th Int. Conf. on Computer Recognition Systems CORES' 05, Springer, 2005, pp. 211–218.
  • [7] KOWAL M., KORBICZ J., Segmentation of breast cancer fine needle biopsy cytological images using fuzzy clustering. In Kornacki J., Raś Z, Wierzchoń S.T., Kacprzyk J. (Eds.) Advances in Machine Learning I, Springer–Verlag, Berlin – Heidelberg, 2010, pp. 405–417.
  • [8] MARCINIAK A., OBUCHOWICZ A., MONCZAK R., KOŁODZIŃSKI M., Cytomorphometry of Fine Needle Biopsy Material from the Breast Cancer, Proc. 4th Int. Conf. on Computer Recognition Systems CORES' 05, Springer, 2005, pp. 603–609.
  • [9] MITCHELL T.M., Machine Learning. McGraw–Hill, 1997.
  • [10] NEZAFAT R., TABESH A., AKHAVAN S., LUCAS C., ZIA M., Feature selection and classification for diagnosing breast cancer, Proc. Int. Assoc. of Science and Technology for Development International Conference, Cancun, Mexico, 1998, pp. 310–313.
  • [11] OBUCHOWICZ A., HREBIEŃ M., NIECZKOWSKI T., MARCINIAK A., Computational intelligence techniques in image segmentation for cytopathology. In Smoliński T.G., Milanova M.G., Hassanien A.–G. (Eds.) Computational intelligence in biomedicine and bioinformatics : current trends and applications, Springer–Verlag, Berlin, 2008, pp. 169–199.
  • [12] SCHNORRENBERG F., PATTICHIS C., KYRIYRIACOU K., SCHIZAS C., Detection of cell nuclei in breast cancer biopsies using receptive fields, IEEE Proc. Engineering in Medicine and Biology Society, 1994, pp. 649–650.
  • [13] STREET N., Xcyt: A system for remote cytological diagnosis and prognosis of breast cancer, In Jain L. (Ed.), Soft Computing Techniques in Breast Cancer Prognosis and Diagnosis, World Scientific Publishing, Singapore, 2000, pp. 297–322.
  • [14] SURI J. S., SETAREHDAN K., SINGH S., Advanced Algorithmic Approaches to Medical Image Segmentation, Springer–Verlag, London, 2002.
  • [15] UNDERWOOD J.C.E., Introduction to biopsy interpretation and surgical pathology, Springer–Verlag, London, 1987.
  • [16] WALKER H. J., ALBERTELLI L., Breast cancer screening using evolved neural networks, Proc. IEEE Int. Conf. on Systems, Man and Cybernetics, San Diego, USA, 1998, pp. 1619–1624.
  • [17] WANG S–L., LAU W–H., LIEW A.W.C., LEUNG S–H., Robust Lip Region Segmentation for Lip Images with Complex Background. Pattern Recognition, Vol. 40, No. 12, 2007, pp. 3481–3491.
  • [18] WOLBERG W.H., STREET W.N., MANGASARIAN O.L., Breast cytology diagnosis via digital image analysis, Analytical and Quantitative Cytology and Histology, Vol. 15, 1993, pp. 396–404.
  • [19] ZOLLER T., VARIGOU, T.A., Robust image segmentation using resampling and shape constraints., IEEE Trans. on Pattern Analysis and Machine Intelligence. Vol. 29, No. 7, 2007, pp. 1147–1164.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-PWA4-0017-0028
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