The influence of bone tissue microstructure' parameters on bone mineral density parameter computed within the computer simulation process

• Autorzy: Binkowski M. , Dyszkiewicz A. , Wróbel Z.
• Języki publikacji: EN

Abstrakty

EN

The given article was created with reference to lack of correlation between results from densitometry test of bone tissue and its mechanical strength. The changes of bone mechanical strength cannot be solely connected with changes of bone mineral density with micro structural construction of bone tissue. The article describes the research using a computer simulation where changes of physical density and parameters of bone microstructure were modelled. The influences of those parameters for changing the bone mineral density have been computed. It has been calculated during simulation process similar to the way it has been provided from densitometry test. The computation process has been carried out on the basis of computer method of simulation of x-ray radiation propagating through the object and had been was created and tested in the previous research. The model of tested object was defined by spatial high resolution distribution of density. The simulation was executed on a sample of bone tissue. The input data to the model of sample were series of cross-sections obtained previously from micro CT of an animal sample. The changes of parameters were simulated in the model based on a method of 2D image processing. The procedure was used to reduce the trabecular surface for all cross-sections. The results of the algorithm were measured during algorithm process. Images were also analyzed by software to measure parameters of microstructure. It gave a chance to estimate the correlation between measured parameter and parameters of microstructure. The applied method of simulation of attenuation of x-ray radiation allowed to produce densitometry image and to compute parameter similar to bone mineral density. The analysis of obtained results shows how the bone mineral density computed from simulation depends on changes of parameters of microstructure.

Słowa kluczowe

EN

densitometry test; bone tissue; bone mineral density; bone microstructure; simulation of attenuation law

PL

badanie densytometryczne; tkanka kostna; gęstość mineralna kości; mikrostruktury kości

• Wydawca: University of Silesia, Institute of Informatics, Computer Systems Department
• Czasopismo: Journal of Medical Informatics & Technologies
• Rocznik: 2005
• Tom: Vol. 9
• Strony: 49--55
• Opis fizyczny: Bibliogr. 18 poz., rys., tab.

Twórcy

autor

Binkowski M.

• Institute of Computer Science, Silesian University, Department of Biomedical Computer Systems Poland, 41-200 Sosnowiec, ul. Będzińska 39

autor

Dyszkiewicz A.

• Institute of Computer Science, Silesian University, Department of Biomedical Computer Systems Poland, 41-200 Sosnowiec, ul. Będzińska 39
• Laboratory of Biotechnology, Poland, 43-400 Cieszyn, ul. Goździków 2
• Silesian Hospital in Cieszyn, Poland, 43-400 Cieszyn, ul. Bielska 4

autor

Wróbel Z.

• Institute of Computer Science, Silesian University, Department of Biomedical Computer Systems Poland, 41-200 Sosnowiec, ul. Będzińska 39

Bibliografia

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