Identyfikatory
Warianty tytułu
Języki publikacji
Abstrakty
The acoustic nonlinearity parameter, B/A, is a fundamental material constant characterizing nonlinear properties of biological media. Knowledge of the B/A of biological fluids or soft tissues through which pulsed acoustic waves generated from clinically relevant probes are propagating is necessary whenever high intensity pressure fields are produced. The numerical model recently developed in our lab, capable of predicting the pulsed sound fields generated from axisymmetric sources in nonlinear attenuating media, was a powerful instrument for investigating nonlinear acoustic fields produced from circular plane or focused sources in attenuating media in dependence on boundary condition parameters. Quantitative analysis of the obtained results enabled developing the alternative method for determination of the B/A parameter of biological media. First, the method involves measuring in the near field of a piezoelectric transducer the nonlinear waveform distortion of the pulsed acoustic wave propagating through the two-layer system of media: water-tested material. Then, the method involves numerical modeling, in frequency domain and under experimental boundary conditions, the nonlinear waveform distortion of the propagating wave by using the Time-Averaged Wave Envelope (TAWE) approach [1]. The obtained numerical simulation results were fitted to the experimental data by adjusting the B/A parameter of the tested material. The determined values of the B/A for standard media considered (corn oil, glycerol, pig blood, homogenized pig liver), whose density, sound velocity and attenuation law have been preliminary determined experimentally, are in a good agreement with those published. The proposed method ensure the decimal degree of accuracy, is relatively simple to use and requires small volume of tested materials that is important because of difficulty of their availability.
Słowa kluczowe
Czasopismo
Rocznik
Tom
Strony
149--158
Opis fizyczny
Bibliogr. 12 poz., tab., wykr.
Twórcy
autor
- Institute of Fundamental Technological Research Polish Academy of Sciences, 00-049 Warsaw, Świętokrzyska 21, Poland, tkujaw@ippt.gov.pl
Bibliografia
- 1. J. Wójcik, A. Nowicki, P. A. Lewin, P.E. Bloomfield, T. Kujawska, L. Filipczyński, Wave envelopes method for description of nonlinear acoustic wave propagation, Ultrasonics, 44, 310-329, 2006.
- 2. G. ter Haar, Therapeutic applications of ultrasound, Progress in Biophysics and Molecular Biology, 93, 111-129, 2007
- 3. P.K. Verma, V.F. Humphrey, F.A. Duck, Broadband measurements of the frequency dependence of attenuation coefficient and velocity in amniotic fluid, urine and human serum albumin solutions, Ultrasound in Med. & Biol., 31, 10, 1375-1381, 2005.
- 4. P.K. Verma, V.F. Humphrey, F.A. Duck, Broadband attenuation and nonlinear propagation in biological fluids: an experimental facility and measurements, Ultrasound in Med. & Biol., 31, 12, 1723-1733, 2005.
- 5. F. Chavrier, C. Lafon, A. Birer, C. Barriere, X. Jacob, D. Cathignol, Determination of the nonlinear parameter by propagating and modeling finite amplitude plane waves, J. Acoust. Soc. Am., 119, 5, 2639-2644, 2006.
- 6. F.P. Curra, P.D. Mourad, V.A. Khokhlova, R.O. Cleveland, L.A. Crum, Numerical simulations of heating patterns and tissue temperature response due to high-intensity focused ultrasound, IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 47, 1077-1089, 2007.
- 7. L. BjOrno, Characterization of biological media by means of their nonlinearity, Ultrasonics, 24, 254-259, 1986.
- 8. L. Filipczyński, T. Kujawska, R. Tymkiewicz, J. Wójcik, Nonlinear and linear propagation of diagnostic ultrasound pulses, Ultrasound in Med. & Biol., 25, 285-299, 1999.
- 9. T. Kujawska, A new method for determination of the acoustic nonlinearity parameter B/A in multilayer biological media, Proc. of the 5th World Congress on Ultrasound, Paris, 81-84, 2003.
- 10. T. Kujawska, J. Wójcik, L. Filipczyński., J. Etienne, A new numerical method for determination of the acoustic nonlinearity parameter B/A in two-layer structures, Proc. of the 7th International Conference on Biomedical Engineering, Kaunas Technological University, 219-222, 2003.
- 11. T. Kujawska, J. Wójcik, Harmonic ultrasound beams forming by means of radiating source Parameters, Hydroacoustics, 7, 135-142, 2004.
- 12. T. Kujawska, J. Wójcik, Nonlinear properties of tissues, Proc. of the Workshop on Ultrasound in Biomeasurements, Diagnostics and Therapy, Gdańsk, 173-182, 2004.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BWMA-0018-0018