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Near infrared transillumination-back scattering (NIRT-BS) : a new method for non-invasive monitoring of changes in width of subarachnoid space and magnitude of cerebrovascular pulsation

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The authors present the medical, physical, and technical background for the new method of near infrared transillumination - back scatetering. The method, for the first time ever, allows for almost complete elimination of the influence of the alterations in skin circulation on the optical signal iDS(t) subtly modulated by the changes in the width of the subarachnoid space (SAS). This has been accomplished through division of the distal or deep optical signal iDS(t) subtly modulated by the changes in the width of the subarachnoid space (SAS). This has been accomplished through division of the distal or deep optical signal iDS(t) over the optical reference signal iPS(t) which is independent of the width of SAS, but depends on the other tissue layers in the same manner as iDS(t). From the obtained quotient, a weak component was extracted that depends on the cerebrovascular pulsation. Described in this paper is the mathematical method of reducing the influence of the changes in skin blood flow on the transillumination signals. A tilt test was used as an example to show the capacity of the method to determine the cerebro-spinal reserve volume.
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bwmeta1.element.baztech-article-BWA2-0005-0252
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