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The high sensitivity time correlated single photon counting system (with photomultiplier tube) for biomedical measurements was designed and tested. Photon time of flight through a parafine wax phantom was modeled by Monte Carlo simulation and next measured by the device. Mean time delay introduced by a phantom is in a good agreement with simulation results. The results presented in this paper demonstrate the feasibility of measuring the optical response with the device.
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301--306
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Bibliogr. 6 poz., il., wykr.
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- Institute of Radioelectronics, Warsaw University of Technology, Nowowiejska 15/19, 00-665 Warsaw, Poland, A.Trybula@ire.pw.edu.pl
Bibliografia
- [1] E. M. C. Hillman, J. C. Hebden, M. Schweiger, H. Dehghani, F. E. W. Schmidt, D. T. Delpy, and S. R. Arridge. “Time resolved optical tomography of the human forearm”, Physics in Medicine and Biology. vol. 46, 2001, pp. 1117-1130.
- [2] J. S. Kapustinsky et al, Nuclear Instruments and Methods A, vol. 241, 1985, p. 612.
- [3] A. B. Milstein, “Three-dimensional optical diffusion tomography with experimental data”, Optics Letters, vol. 27, no. 2, 2002, pp. 95-97.
- [4] F. E. W. Schmidt, M. E. Fry, E. M. C. Hillman, J. C. Hebden, and D. T. Delpy, “A 32-channel time-resolved instrument for medical optical tomography”, Review of Scientific Instruments, vol. 71, no. 1, Jan. 2000.
- [5] A. Trybuła, G. Domański, B. Konarzewski, J. Marzec, and K. Zaremba, “System do pomiaru czasu przelotu fotonów przez tkankę”, Elektronika vol. 11, 2009, pp. 143-145, [in polish].
- [6] L. Wang, S. Jacques, and L. Zheng, “MCML - Monte Carlo modeling of light transport in multi-layered tissues”, Computer Methods and Programs in Biomedicine, vol. 47, 1995, pp. 131-146.
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Bibliografia
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bwmeta1.element.baztech-article-BWA0-0046-0014