Medyczne zastosowania sit molekularnych

• Autorzy: Długopolska K. , Ruman T. , Pogocki D. , Danilczuk M.

Warianty tytułu

EN

Medical applications of molecular sieves

• Języki publikacji: PL

Abstrakty

EN

Molecular sieves are porous, crystalline materials usually synthetic or natural zeolites, that contain well-defined pores of precise and uniform size. The term zeolite originally described a group of natural crystalline aluminosilicates, however nowadays the term covers many different materials such as aluminophosphates or gallium-silicalites. During the last few decades microporous and mesoporous materials have been considered for medical use due to biological properties and stability in biological environment [1-4]. Zeolites have been investigated as drug carriers, dietetic supplements, antimicrobial agents or as adjuvants in anticancer therapy [3–9]. Unique "magnetic" zeolite was obtained by Shan et al. Zeolite nanocrystals were in situ combined with superparamagnetic magnetite (Fe3O4) nanoparticles in the hydrothermal synthesis procedure. An high amount of enzymes adsorption and a good biocatalytic performance is shown by those newly formed magnetite/zeolite composite nanoparticles [15]. Zeolite of the CuX type has been used as a support for a antitumoral drug-cyclophosphamide. The in vivo tests show that the intensity of the antitumoral effects of the CuX zeolitecyclophosphamide system is similar in comparison to the one achieved by cyclophosphamide alone [21]. Ion-exchanged zeolites have also been used as a novel approach to storage and delivery of nitric oxide (NO) [16]. Zeolite surface coatings offer antimicrobial protection through the controlled release of antimicrobial agent and can be applied to different types of surfaces or incorporated in many types of polymers [17, 18]. Rivera group prove that both zeolitic materials and drugs could be simultaneously administrated to a patient without any loss of an individual pharmaceutical effect of each product [22]. Zeolite matrix has been also used to stabilize erythromycin solutions. An existing commercial product based on diisopropylsebacate/ethanol solution of 4% erythromycin and zinc acetate (ZinerytŽ, Yamanouchi Pharma) has been compared to analogical system where active compounds are loaded into porous material [26]. Natural clinoptilolite is the main and active component of the antidiarrheal drug acting as adsorbent of bile acids, Aflatoxine B and Glucose [64]. Recent studies show that this material can also be utilized as an adjuvant in anticancer therapy [10–13, 46–47]. The new antacid drug NeutacidŽ is based on the neutralizing capacity of the purified natural zeolite – clinoptilolite from the Tasajera deposit (Cuba) for therapy of patients suffering from hyperacidity produced by gastric dyspepsia and gastric-duodenal ulcer [50]. Mesoporous material MCM-41, due to the pore size tunability and functionalization possibilities, can especially encapsulate a variety of different drug molecules and release them in controlled ways [27, 28, 30–36]. Zeolites containing silver ions are used as antimicrobial agents [53–57]. Zeolites are the main ingredient of commercially available anti-bleed agents [67].

Słowa kluczowe

PL

materiały mikroporowate; materiały mezoporowate; zeolity; nośniki leków; systemy transportu leków

EN

microporous materials; mesoporous materials; zeolite; drug delivery systems; drug carriers

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Wiadomości Chemiczne
• Rocznik: 2009
• Tom: [Z] 63, 11-12
• Strony: 1073--1088
• Opis fizyczny: bibliogr. 69 poz., wykr.

Twórcy

autor

Długopolska K.

autor

Ruman T.

autor

Pogocki D.

autor

Danilczuk M.

• Politechnika Rzeszowska, Wydział Chemiczny, al. Powstańców Warszawy 6, 35-959 Rzeszów,

Bibliografia

• [1] C.K. Hersh, Molecular Sieves, Reinhold Pub. Corp., New York, 1961.
• [2] D.W. Breck, Zeolite Molecular Sieves, Wiley, New York, 1973.
• [3] D.W. Breck, Zeolite Molecular Sieves: Structure, Chemistry, and Uses, John Wiley & Sons, New York, 1974, pp. 634-641.
• [4] E.M. Flanigen, L.B. Sand, Molecular Sieve Zeolite - I, ACS, Washington, 1971.
• [5] T. Ceyhan, M. Tatlier, H.J. Akcakaya, Mater. Sci. Mater. Med., 2007, 18, 1557.
• [6] W.G. Pond, L.P. Krook, H. Ho, D.R. Su, P.A. Schoknecht, Bull. Env. Contam. Toxicol., 1996, 57, 713.
• [7] N. Zarkovic, K. Zarkovic, M. Kralj, S. Borovic, S. Sabolovic, M.P. Blazi, A. Cipak, K. Pavelic, Anticancer Res., 2003, 23, 1589.
• [8] Y.H. Zhang, X.J. Yu, X.Y. Wang, W. Shan, P.Y. Yang, Y. Tang, Chem. Comm., 2004, 2882.
• [9] Y.H. Zhang, X.J. Yu, X.Y. Wang, W. Shan, B.Y,Wu, H. Z. Fan, X. J. Yu, Y. Tang, P.Y. Yang, Ang. Chem. Int. Ed., 2005, 44, 615.
• [10] T. Yu, Y.H. Zhang, C.P. You, J.H. Zhuang, B. Wang, B.H. Liu, Y.J. Kang, Y. Tang, Chem.-A Eur. J., 2006, 12, 1137.
• [11] C. Platas-Iglesias, L. Van der Elst, W.Z. Zhou, R.N. Muller, C.F.G.C. Geraldes, T. Maschmeyer, Peters, J.A. Chem.-A Eur. J., 2002, 8, 5121.
• [12] A. Dyer, S. Morgan, P. Wells, C. Williams, J. Helminthol., 2000, 74, 137.
• [13] A. Dyer, P. Wells, C. Williams, 2007, Patent: PTC. INT.APPL. WO 8705, 504.
• [14] S.K. Shaker, A. Dyer, D.M. Storey, J. Helminthol., 1992, 66, 288.
• [15] H.M. Ötker, I.J. Akmehmet-BalcIoglu, J. Hazard. Mater., 2005, 122, 251.
• [16] M. Arruebo, R. Fernandez-Pacheco, S. Irusta, J. Arbiol, M.R. Ibarra, J. Santamaria, J. Nanotechnology, 2006, 17, 4057.
• [17] W. Shan, T. Yu, B. Wang, J. Hu, Y. Zhang, X. Wang, Y. Tang, Chem. Mater., 2006, 18, 3169.
• [18] P.S. Wheatley, A.R. Butler, M.S. Crane, S. Fox, B. Xiao, A.G. Rossi, I.L. Megson, R.E. Morris, J. Am. Chem. Soc., 2006, 128, 502.
• [19] M.C. Frost, M.E. Meyerhoff, J. Biomed. Mater. Res. A. 2005, 72A, 409.
• [20] M.R. Miller, I.L. Megson, Br. J. Pharmacol., 2007, 151, 305.
• [21] A. Rivera, T. Farias, Micropor. Mesopor. Mater., 2005, 80, 337.
• [22] A. Rivera, T. Farias, A.R. Ruiz-Salvador, L.C. de Menorval, Micropor. Mesopor. Mater., 2003, 61, 249.
• [23] C.V. Uglea, I. Albu, A. Vatajanu, M. Croitoru, S. Antoniu, L. Panaitescu, R.M.J. Ottenbrite, J. Biomater. Sci. Polymer Ed., 1994, 6, 633.
• [24] T. Farias, A.R. Ruiz-Salvador, A. Rivera, Micropor. Mesopor. Mater., 2003, 61, 117.
• [25] M.G. Rimoli, M.R. Rabaioli, D. Melisi, A. Cucio, S. Mondello, R. Mirabelli, E. Abignete, J. Biomed. Mater. Res. A. 2008, 87A, 156.
• [26] C.F. Linares, S. Solano, G. Infante, Micropor. Mesopor. Mater., 2004, 74, 105.
• [27] M.C. Bonferoni, G. Cerri, M. de' Gennaro, C. Juliano, C. Caramella, App. Clay. Sci., 2007, 36, 95.
• [28] G. Cerri, M. de'Gennaro, M.C. Bonferoni, C. Caramella, App. Clay. Sci., 2004, 27, 141.
• [29] A. Ramila, B. Munoz, J. Perez-Pariente, M. Vallet-Regi, J. Sol- Gel Sci. Technol., 2003, 26, 1199.
• [30] M. Vallet-Regi, A Ramila, R.P. del Redl, J. Perez-Pariente, Chem. Mater., 2001, 13, 308.
• [31] S. Inagaki, S. Guan, Y. Fukushima, T. Ohsuma, O. Terasami, J. Am. Chem. Soc., 1999, 121, 9611.
• [32] B. Munoz, A. Ramila, J. Perez-Pariente, I. Diaz, M. Vallet-Regi, Chem. Mater., 2003, 15, 500.
• [33] C. Tourne-Peteilh, D. Brunel, S. Begu, B. Chiche, F. Fajula, D.A. Lerner, J.M. Devoisselle, New J. Chem., 2003, 27, 1415.
• [34] A. Vinu, K.Z. Hossain, K.J Ariga, Nanosci. Nanotechnol., 2005, 5, 347.
• [35] A. Vinu, T. Mori, K. Ariga, Sci. Technol. Adv. Mater., 2006, 7, 753.
• [36] T. Kokubo, H. Kushitani, S. Sakka, T. Kitsugi, T. Yamamuro, J. Biomed. Mater. Research., 1990, 24, 721.
• [37] M. Manzano, V. Aina, C.O. Arean, F. Balas, V. Cauda, M. Colilla, M.R. Delgado, M. Vallet-Regi, Chem. Eng. J., 2008, 137, 30.
• [38] C. Charnay, S. Begu, C. Tourne-Peteilh, L. Nicole, D.A. Lerner, J.M. Devoisselle, Eur. J. Pharm. Biopharm., 2004, 57, 533
• [39] C.A. Aerts, E. Verraedt, R. Mellaerts, A. Depla, P. Augustijns, J. Van Humbeeck, G. Van den Mooter, J.A. Martens, J. Phys. Chem. C., 2007, 111, 13404.
• [40] T. Heikkila, J. Salonen, J. Tuura, N. Kumar, T. Salmi, D.Y. Murzin, M.S. Hamdy, G. Mul, L. Laitinen, A.M. Kaukonen, J. Hirvonen, V.P. Lehto, Drug Delivery., 2007, 15, 337.
• [41] T. Limnell, J. Riikonen, J. Salonen, A.M. Kaukonen, L. Laitinen, J. Hirvonen, V.P. Lehto, Int. J. Pharm., 2007, 343, 141.
• [42] T. Azais, C. Tourne-Peteilh, F. Aussenac, N. Baccile, C. Coelho, J.M. Devoisselle, F. Babonneau, Chem. Mater., 2006, 18, 6382.
• [43] K.A. Fisher, K.D. Huddersman, M.J. Taylor, Che. A Eur. J., 2003, 9, 5873.
• [44] Q. Tang, Y. Xu, D. Wu, Y. Sun, J. Solid State Chem., 2006, 179, 1513.
• [45] D. Zhao, Q. Huo, J. Feng, B.F. Chmelka, G.D. Stucky, J. Am. Chem. Soc., 1998, 120, 6024.
• [46] D. Zhao, J. Feng, Quo. Huo, N. Melosh, G.H. Fredrickson, B.F. Chmelka, G.D. Stucky, Science, 1998, 279, 548.
• [47] A.L. Doadrio, E.M.B. Sousa, J.C. Doadrio, J. Perez-Pariente, I. Izquierdo-Barba, M. Vallet-Regi, J. Control. Release., 2004, 97, 125.
• [48] M. Colic, K. Pavelic, J. Mol. Med., 2000, 78, 333.
• [49] K. Pavelic, M. Hadzija, L. Bedrica, I. Dikic, M. Katic, M. Kralj, M. Bosnar Herak, S. Kapitanovic, M. Poljak-Blazi, S. Krizanac, R. Stojkovic, M. Jurin, B. Subotic, M. Colic, J. Mol. Me., 2001, 78, 708.
• [50] S. Ivkovic, D. Zabcic, Free. Rad. Biol. Med., 2002, 33, S331.
• [51] S. Ivkovic, P. Bendzko, J. Schulz, Free. Rad. Biol. Med., 2004, 37, S173.
• [52] G. Rodriguez-Fuentes, A.R. Denis, M.A.B Alvarez, A. Iraizoz Colarte, Micropor. Mesopor. Mater. 2006, 94, 200.
• [53] A. Rivera, G. Rodriguez-Fuentes, E. Altshuler, Micropor. Mesopor. Mater., 1998, 24, 51.
• [54] K.L. Watkins, L.L. Southern, Poultry Sci. 1992, 71, 1048.
• [55] C.R. O'Neill, D.E. Beving, W. Chen, Y. Yan, AIChE Journal, 2006, 52, 1157.
• [56] D.E. Beving, C.R. O'Neill, Y. Yan, Micropor. Mesopor. Mater. 2008, 108, 77.
• [57] P. Rusin, K. Bright, C. Gerba, Lett. Appl. Microbiol., 2003, 36, 69.
• [58] K. Bright, C. Williams, M.A. Kenward, I. Radecka, J. App. Microbiol. 2008, 104, 1516.
• [59] S. Suarez, A. Devaux, J. Banuelos, O. Bossart, A. Kunzmann, G. Calzaferri, Adv. Funct. Mat., 2007, 17, 2298.
• [60] R. Francis, 2007, US Patent 20070259017.
• [61] R. Niira, T. Yamamoto, M. Uchida, 1996, US Patent 5556699.
• [62] J.E. Barry, J.A. Trogolo, 2006, US Patent 6582715.
• [63] M. Kralj, K. Pavelic, EMBO Reports 2003, 4, 1008.
• [64] M. Hotta, H. Nakajima, K. Yamamoto, M. Aono, J. Oral Rehabil., 1998, 25, 485.
• [65] M. Grce, K. Pavelic, Micropor. Mesopor. Mater., 2005, 79, 165.
• [66] G. Rodriguez-Fuentes, M.A. Barrios, A. Iraizoz Colarte, I. Perdomo, B. Cedre, Zeolites, 1997, 19, 441.
• [67] K. Pavelic, M. Katic, V. Sverko, T. Marotti, B. Bosnjak, T. Balog, R. Stojkovic, M. Radacic, M. Colic, M. Poljak-Blazi, J. Cancer. Res. Clin. Oncol., 2002, 128, 37.
• [68] A.J. Ramos, J. FinkGremmels, E. Hernandez, J. Food. Prot., 1996, 59, 631.
• [69] X.F. Hyrsey, F.J. Dechene, 1989, US Patent 4822349.