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Związki zakłócające procesy hormonalne -badania ekotoksykologiczne
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Abstrakty
Endocrine disrupting compounds (EDCs) have the potential to alter hormone pathways that regulate life processes in humans, vertebrates and invertebrates. Besides xenobiotics having endocrine effects, there arc naturally occurring estrogenie compounds. The limited number of studies with EDCs in invertebrates is partially due to the fact that their hormonal systems arc rather poorly understood in comparison with vertebrates. It is also important, but difficult to discriminate between hormone - mediated and other toxicological modes of action. Data of the potentially adverse impact of EDCs on wildlife species arc reviewed.
Związki zakłócające procesy hormonalne (EDs - endocrine disruptors) zmieniają funkcje hormonów regulujących przemiany fizjologiczne u ludzi, kręgowców i bezkręgowców. Do tych związków należą zarówno ksenobiotyki jak i substancje pochodzenia naturalnego między innymi o charakterze estrogenów. W piśmiennictwie jest niewiele danych o systemach hormonalnych u bezkręgowców i zaburzeniach w ich funkcjach pod wpływem zanieczyszczeń. W artykule podano informacje mające na celu przybliżenie problemów metodycznych w badaniach ckotoksykologicznych wybranych ED na niektórych grupach bezkręgowców.
Czasopismo
Rocznik
Tom
Strony
81--88
Opis fizyczny
bibliogr. 25 poz., tab.
Twórcy
autor
autor
- Warsaw University of Technology, Department of Environmental Biology ul. Nowowiejska 20, 00-653, Warsaw, Poland
Bibliografia
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- [9] Fossi M.C., S. Casini, L. Marsili, S. Ancora, G. Mori, L. Neri, T. Romeo, A. Ausili: Evaluation of ecotoxicological effects of endocrine disrupters during a four-year survey of the Mediterranean population of swordfish (Xiphias gladius), Marine Environmental Research, 58, 425-^129 (2004).
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- [20] Petit F., P. Le Goff, J.-P. Cravedi, Y. Valotaire, F. Pakdel: Two complementary bioassays for screening the estrogenie potency ofxenobiotics: recombinant yeast for trout estrogen receptor and trout hepatocyte cultures, Journal of Molecular Endocrinology, 19, 321-335 (1997).
- [21] Safe S.: Endocrine disruptors and human health: is there a problem, Toxicology, 205, 3-10 (2004).
- [22] Sapozhnikova Y., D. Schlenk, A. Mc Elroy, S. Snyder: Estrogenie activity measurement in wastewater using in vitro and in vivo methods, [in:] Techniques in Aquatic Toxicology, 2. cd., G.K. Ostrandcr, Taylor and Francis, CRC, 2005.
- [23] Soin T., G. Smagghc: Endocrine disruption in aquatic insects: a review, Ecotoxicology, 16, 83-93, (2007).
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Typ dokumentu
Bibliografia
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bwmeta1.element.baztech-article-BUS5-0004-0038