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Immobilizacja enzymów. Część 2: Reaktory membranowe

Autorzy
Identyfikatory
Warianty tytułu
EN
Enzymes immobilization. Part 2: Membrane reactors
Języki publikacji
PL
Abstrakty
EN
Biocatalysis involves the enzyme-promoted transformations of a substrate into useful product in either a homogeneous or heterogenous system. The separation of reactants from products and the recovery and reuse of the catalyst from the reaction mixture is an important step that significantly decreases the cost of the process. Membrane reactors constitute an attempt to integrate catalytic conversion, product separation and/or concentration, and catalyst recovery into a single operation unit that lowers the overall cost of final product. In an enzyme membrane reactor biocatalyst is immobilized within the reaction vessel or on/in a membrane (catalytic membrane). The paper shows two possibilities for immobilization of enzymes: 1 - localization of the soluble biocatalyst in a certain defined region of space of a membrane reactor; e.g. a volume of a reactor and separation unit or in lumen/shell side of ultrafiltration unit; 2 - adsorbed, deposited or bound (physically, via affinity ligand or by covalent attachment) to the surface of a membrane or entrapped within pores or material of the membrane. Arguments counting for membrane supported or soluble enzymes are also presented. Reactors with soluble biocatalyst in a volume of a membrane reactor seem be suited to carry out complex enzymatic transformations, involving several enzymes and cofactor regeneration. Membrane reactors with catalytic membranes are particularly appropriate for nonconventional media such as organic-aqueous two-phase systems and for production of biosensing elements of enzyme electrodes. It is therefore the intention of the paper to outline the common immobilization methods and technologies to facilitate proper applications of enzymes immobilized in a membrane reactor.
Rocznik
Strony
747--780
Opis fizyczny
Bibliogr. 140 poz., rys., tab.
Twórcy
autor
  • Instytut Inżynierii Chemicznej, Politechnika Wrocławska, ul. Norwida 4/6, 50-373 Wrocław
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Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BUS2-0006-0040
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