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Gene Expression by Software Mechanisms

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Wybrane pełne teksty z tego czasopisma
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Języki publikacji
EN
Abstrakty
EN
This paper describes the molecular interactions and coordination of cell processes using computer operating system concepts related to synchronization and communication. We argue that in molecular biology, the genes and their chromatin context provide communication and interaction with various cell processes in a similar way to that in which computer processes synchronize and communicate with each other.
Wydawca
Rocznik
Strony
67--80
Opis fizyczny
bibliogr. 17 poz.
Twórcy
autor
autor
  • Institute of Computer Science, Romanian Academy, Iasi, Romania
Bibliografia
  • [1] T. H. Bestor: Methylation Meets Acetylation, Nature 393, 311-312,1998.
  • [2] D. Bray: Protein molecules as computational elements in living cells, Nature 376,3 07-31 2,1 995.
  • [3] D. Bray: Reductionism for biochemists-how to survive the protein jungle, Trends in Biochemical Sciences 22, 3 25-326 ,1997.’
  • [4] G. Ciobanu, B. TanasS: An Operating System View to Molecular Processes, Chinese Journal of Computers, Special Volume on Molecular Computing, 2002.
  • [5] T. Cremer, C. Cremer: Chromosome territories, nuclear architecture and gene regulation in mammalian cells. Nature Genetics 2(1), 292-301,2001.
  • [6] C. Francastel, D. Schubeler, D. Martin, M. Groudine: Nuclear Compartmentalization and Gene Activity, Nature Reviews M olecular Cell Biology 1, 137-143,2000.
  • [7] L.L. Hartwell, J. Hopfield, S. Leibler, A. Murray: From molecular to modular cell biology, Nature 402, supp: C47-C52, 1999.
  • [8] R. M . Metcalfe, D. R. Boggs: Ethernet: Distributed packet switching for local computer networks, Comm. ACM, 19(7), 1976.
  • [9] M. Misteli: Protein dynamics: implications fornuclear architecture and gene expression, Science 291, 843- 847, 2001.
  • [10] X. Nan, H. Ng, C. Johnson, C. Laherty, B. Taimer, R. Eisenman, A. Bird: Transcriptional Repression by the Methyl-CpG-binding Protein MeCP2 Involves a Histone Deacetylase Complex, Nature 393, 386-389,1998.
  • [11] B. Palsson: The challenges of in silico biology, Nature Biotechnology 18,114 7-1 150,2000.
  • [12] R. C. Paton: Some computational models at the cellular level, BioSystems 2 9,63 -75,1 99 3.
  • [13] Gh. PSun: Computing with membranes, Journal of Computer and System Sciences, 61(1), 108-143,2000.
  • [14] N. Proudfoot: Connecting transcription to messenger RNA processing, Trends in Biochemical Sciences 25, 290 -293,2000 .
  • [15] D. Schubeler, C. Francastel, D. M. Cimbora, A. Reik, D.I.K. Martin, M. Groudine: Nuc lear localization and histone acetylation: a pathway for chromatin opening a nd transcriptional activation of the /3-globin locus. Genes & Development 14,940-950,2000.
  • [16] G. S.Stein, M. Montecino, A. J. van Wijnen, J. L. Stein, J. B. Lian: Nuclear structure-gene expression interrelationships: implications for aberrant gene expression in cancer, LGancer Research 60, 2067-2076, 2000.
  • [17] B. D. Strahl, C. D. Allis: The language of covalent histone modifications, Nature 4 03 ,41 -45,2 000.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BUS2-0003-0102
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