Mikrocystyny sinic w zbiornikach wodnych

• Autorzy: Gajdek P.

Warianty tytułu

EN

Microcystins in water reservoirs

• Języki publikacji: PL

Abstrakty

EN

Many species of cyanobacteria forming blooms in eutrophic waters produce toxins. They are cytotoxins, neurotoxins, hepatotoxins and dermatotoxins. The hepatotoxins can be divided into microcystins and nodularins, cyclic hepta- and pentapeptides respectively. About 60 microcystins have been characterized and the most common is microcystin-LR, but their chemical structure may be also different. Since a long time cyanobacterial toxins have been the reason of lethal poisonings of wild and domestic animals and health problems of humans in different regions of the world. In 1996 in Brazil about 60 haemodialysis patients died after getting a lethal microcystin dose intravenously. The most frequent signs of poisoning are anorexia, general weakness, diarrhoea and vomiting. Microcystins repeatedly uptaken by organisms in trace amounts contribute to the development of cancer as a result of their inhibition of protein phosphatase 1 and 2A. There are epidemiological data indicating high rates of cancer in China due to long term exposure to cyanobacterial toxins in water. World Health Organization proposed 1 microgram per litre as a guideline value for maximum acceptable level of microcystin-LR or its equivalents in drinking water. Microcystins are chemically very stable and can not be decomposed by acid, alkaline or boiling. In field conditions their degradation is minimal. They are also difficult to decompose in water treatment processes. Conventional water treatment methods are not sufficient, while activated carbon filtration or ozonation makes them more effective, but still trace amounts of microcystins pass the full-scale treatment. Many methods of degradation or chemical modification of microcystins have been devised. Unfortunately, despite large body of research work cyanobacterial toxins are still dangerous, especially in drinking water reservoirs. In Poland, the cyanobacterial blooms in drinking water reservoirs constitute a serious problem, especially for large agglomerations. For instance in summer 1993 in Sulejowski reservoir being a drinking water source for the city of Łódź the microcystin content in a cyanobacterial bloom was in the range of 40 - 117 mg/g dry mass of phytoplankton, reaching in the following years the value of 427 mg/g dry mass of phytoplankton, which was in the years 1995 and 1996 on the average 5.7ug/L. In the samples gathered in 1996 in Jeziorsko and Zalew Włocławski the average microcystin content was around 300 mg/g dry mass of phytoplankton. The presence of cyanobacterial toxins in Polish lakes and water reservoirs establishes new problems for Polish waterworks and laboratories dealing with water quality analysis. This article contains many hints on construction of experimental set-ups for the determination of cyanobacterial toxins in water reservoirs, in particular sampling methods, choice of filters for separation of cyanobacterial cells, parameters in sample enrichment by means of solid-phase extraction and analysis with high performance liquid chromatography, detection methods, etc.

Słowa kluczowe

PL

mikrocystyny; toksyny sinic; oznaczanie toksyn w wodzie; metoda fizykochemiczna

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Wiadomości Chemiczne
• Rocznik: 2000
• Tom: [Z] 54, 7-8
• Strony: 637--650
• Opis fizyczny: bibliogr. 57 poz.

Twórcy

autor

Gajdek P.

• Zakład Fizjologii i Biologii Rozwoju Roślin, Instytut Biologii Molekularnej, Uniwersytet Jagielloński al. Mickiewicza 3, 31-120 Kraków

• Zakład Fizjologii i Biologii Rozwoju Roślin, Instytut Biologii Molekularnej, Uniwersytet Jagielloński al. Mickiewicza 3, 31-120 Kraków

Bibliografia

• [1] K. Sivonen, Mycotoxins and Phycotoxins - Deoelopments in Chemistry, Toxicology and Food Safety, 1998, s. 547.
• [2] M. Rogalska-Kupiec, T. Bochnia, Wiad. Botaniczne, 1998, 42, 11.
• [3] W. W. Charmiehael, Adv. Botanical Res., 1997, 27, 211.
• [4] K. Sivonen, Phycologia, 1996, 35, 12.
• [5] W. W. Carmichael, Scientific American, 1994, 270, 78.
• [6] M. Tarczyńska, M. Zalewski, Gosp. Wodna, 1995, 4, 83.
• [7] M. Tarczyńska, M. Zalewski, Zintegrowana strategia ochrony i zagospodarowania ekosystemów wodnych, „Biblioteka Monitoringu Środowiska”, Uniwersytet Łódzki 1994, s. 79.
• [8] M. Tarczyńska, K. Izydorczyk, M. Zalewski, Raport o stanie środowiska w województwie sieradzkim w lalach 1995-1996, „Biblioteka Monitoringu Środowiska”, Sieradz 1997 s. 145.
• [9] A. K. M. Kabziński, H. Scholl, Ogólnopolskie Sympozjum: Problemy analityczne oznaczania substancji rakotwórczych w wodach, Państwowy Zakład Higieny, Warszawa, materiały konferencyjne, 1997, 121.
• [10] A. K. M. Kabziński, H. Scholl, S. Domagała. Biological Processes in Recultivation of Lakes, Łódź 1995, s. 221.
• [11] M. R. Prinsep, F. R. Caplan, R. E. Moore, G. M. L. Patterson, R. E. Honkanen, A. L. Boynton, Phytochemistry, 1992, 31, 1247.
• [12] K. L. Rinehart, M. Namikoshi, B. W. Choi. J. Appl. Phycology. 1994, 6, 159.
• [13] G. A. Godd, C. J. Ward, K. A. Beattie, S. G. Bell, The Phototrophic Prokaryotes, Kluwer Akademie, New York 1999, 623.
• [14] S. Pouria, A. de Andrade, J. Barbosa, R. L. Cavalcanti, V. T. S. Barreto, C. J. Ward, W. Preiser, G. K. Poon, G. N. Neild, G. A. Codd, Lancet, 1998, 352, 21.
• [15] E. M. Jochimsen, W. W. Carmichael, J. An, D. M. Cardo, S. T. Cookson, C. E. M. Holmes, M. B. de C. Antunes, D. A. de M. Filho, T. M. Lyra, V. S. T. Barreto, S. M. F. O. Azzevdo, W. R. Jarvis, New Engl. J. Mei, 1998, 338, 883.
• [16] R. M. Dawson, Toxicon, 1998, 36, 953.
• [17] M. Craig, H. A. Luu, T. L. McCready, D. Williams, R. J. Andersen, C. F. B. Holmes, Biochem. Cell Biol., 1996, 74, 569.
• [18] T. Abe, T. Lawton, J. D. B. Weyers, G. A. Codd, New Phytologist, 1996, 133, 651.
• [19] G. A. Codd, J. S. Metcalf, K. A. Beattie, Toxicon, 1999, 37, 1181.
• [20] Y. Ueno, S. Nagata, T. Tsutsumi, A. Hasegawa, M. F. Watanabe, H.-D. Park, G.-C. Chen, G. Chen, S.-Z. Yu, Carcinogenesis, 1996, 17, 1317.
• [21] P. Gajdek, Postępy Biol. Kom., 1999, 26, 743.
• [22] T. W. Lambert, C. F. B. Holmes, S. E. Hrudey, Water Res., 1996, 30, 1411.
• [23] K. Himberg, A.-M. Keijola, L. Hiisvirta. H. Pyysalo. K. Swonen, Water Res., 1989, 23, 979.
• [24] J. Meriluoto, A.-S. Harmala-Brasken, J. Eriksson, D. Toi vola, T. Lindholm, Phycologia, 1996, 35, 125.
• [25] L. Shi, W. W. Carmichael, I. Miller, Arch. Microbiol., 1955, 163, 7.
• [26] M. F. Watanabe, K. Tsuji, Y. Watanabe, K.-I. Harada, M. Suzuki, Natural Toxins, 1992, 1, 48.
• [27] M. Ikawa, N. Phillips, J. F. Haney, J. J. Sasner, Toxicon, 1999, 37, 923.
• [28] W. W. Carmichael, P. R. Gorham, The Water Environment. Algal Toxins and Health, Plenum Press, New York 1981, s. 161.
• [29] M. M. Watanabe, K. Kaya, N. Takamura, J. Phycology, 1992, 28, 761.
• [30] R. L. Oliver, J. Phycology, 1994, 30, 161.
• [31] L. A. Lawton, C. Edwards, G. A. Codd, Analyst, 1994, 119, 1525.
• [32] G. J. Jones, I. R. F alcomer, R. M. Wilkins, Environ. Toxicol. Water Qual., 10,19.
• [33] C. Rivasseau, S. Martins, M.-C. Hennion, J. Chromatogr. A, 1998, 799, 155.
• [34] R. J. Wicks, P. G. Thiel, Eniiron. Sei. Technol., 1990, 24, 1413.
• [35] K.-I. Harada, K. Matsuura, M. Suzuki, H. Oka, M. F. Watanabe, S. Oishi. A. M. Dahlem, V. R. Beasley, W. W. Carmichael, J. Chromatogr., 1988, 448, 275.
• [36] T. Trishnamurthy, W. W. Carmichael, E. W. Sawer, Toxicon, 1986, 24, 865.
• [37] K. Tsuji, S. Naito, F. Kondo, M. F. Watanabe, S. Suzuki, H. Nakazawa, M. Suzuki, T. Shimada, K.-I. Harada, Toxicon, 1994, 32, 1251.
• [38] M.-C. Hennion, V. Pichon, Eniiron. Sei. Technol., 1994, 28, 576.
• [39] J. Meriluoto, Anal. Chim. Acta, 1997, 352, 277.
• [40] C. Edwards, L. A. Lawton, S. M. Coyle, P. Ross, J. Chromatogr. A, 1996, 734, 175.
• [41] K. Tsuji, S. Naito, F. Kondo, N. Ishikawa, M. F. Watanabe, M. Suzuki, K.-L Harada, Environ. Sei. Technol., 1994, 28, 173.
• [42] L. A. Lawton, C. Edwards, K. A. Beattie, S. Pleasance, G. J. Dear, G. A. Codd, Natural Toxins, 1995, 3, 50.
• [43] K.-I. Harada, K. Matsuura, M. Suzuki, M. F. Watanabe, S. Oishi, A. M. Dahlem, V. R. Beasley. W. W. Carmichael, Toxicon. 1990. 28. 55.
• [44] F. Kondo, Y. Ikai, H. Oka, H. Matsumoto, S. Yamada, N. Ishikawa, K. Tsuji, K.-I. Harada, T. Shimada, M. Oshikata, M. Suzuki, Natural Tocins, 1995, 3, 41.
• [45] K.-I. Harada, M. Oshikata, T. Shimada, A. Nagata, N. Ishikawa, M. Suzuki, F. Kondo, M. Shimizu, S. Yamada, Natural Toxins, 1997, 5, 201.
• [46] H. Murata. H. Shoji, M. Oshikata. K.-I. Harada M. Suzuki, F. Kondo, H. Goto, J. Chromatogr. A, 1995, 693, 263.
• [47] M. Yuan, M. Namikoshi, A. Otsuki, K. L. Rinehart, K. Sivonen, M. F. Watanabe, J. Mass Spectr., 1999, 34, 33.
• [48] M. Namikoshi, M. Yuan. K. Sivonen. W. W. Carmichael, K. L. Rinehart, L. Rou-hiainen, F. Sun, S. Brittain, A. Otsuki, Chem. Res. Toxicol., 1998, 11, 143.
• [49] F. Kondo, Y. Ikai, H. Oka, N. Ishikawa, M. F. Watanabe, M. Watanabe, K. il. Harada, M. Suzuki, TToT^c^c^ii,199^, 30,217.
• [50] J. Merilugto, B. Kincaid, M. R. Smyth, M. Wasberg, J. Chromatogr. A, 1998, 810,226.
• [51] H. S. Lee, C. K. Jeong, H. M. Lee, S. J. Choi, K. S. Do, K. Kim, Y. H. Kim, J. Chromatogr. A, 1999, 848, 179.
• [52] K. P. Bateman, P. Thibault, D. J. Douglas, R. L. White, J. Chromatggd. A, 1995, 717, 253.
• [53] K L. Harada, M. Suzuki, A. M. Dahlem, V. R. Beasley, W. W. Carmichael, K. L. Rinehart Jr., Toxicon, 1998, 26, 433.
• [54] I. Ojanpera, A. Pelander, E. Vugr^, K. Himberg, M. Waris, K. Niinivaara, J. Planar Chromatogr., 1995, 8, 69.
• [55] T. Sano, K. Nohara, F. Shiraishi, K. Kaya, Int. J. Environ. Anal. Chem., 1992, 49, 163.
• [56] K.-I. Harada, H. Murata, Z. Qiang, M. Suzuki, F. Kondo, Toxicon, 1996, 34, 701.
• [57] K. Kaya, T. Sano, Anal. Chim. Acta, 1999, 386, 107.

Uwagi

PL

Opracowanie rekordu ze środków MEiN, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2022-2023).