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We developed a program which allows measurement of consecutive time intervals between chosen events in ECG, carotid pulse, and phonocardiogram. Currently it is possible to determine following systolic time intervals (STI): PEP - pre-ejection period, Q-S2 – time between trough of Q wave and aortic valve closure, Q-D - time between trough of Q wave and dicrotic notch, S2-D - time between aortic valve closure and dicrotic notch, as well as QQ interval. Measurements were performed on 30 young, healthy subjects. Subjects were supine, they performed two-minute isometric handgrip (HG) twice. First HG was followed by four-minute rest, second HG by two-minute occlusion of the working arm. Preliminary analyses revealed: 1/ the QQ interval changes were reflected weakly or not at all in changes of STI, 2/ shortening of QQ during handgrip was paralleled by slight decrease of Q-D and Q-S2, 3/ during occlusion, when QQ intervals returned to baseline also Q-D and Q-S2 returned to baseline, despite sustained elevation of arterial pressure, 4/ there were distinct oscillation in the time course of Q-S2 intervals, time course of Q-D intervals was relatively smooth, thus S2 and D may reflect different events contrary to common notation.
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13--16
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Bibliogr. 9 poz., rys.
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autor
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autor
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- Department of Applied Physiology, Mossakowski Medical Research Centre Polish Academy of Sciences
Bibliografia
- [1] S. S. Ahmed, G. E. Levinson, C.J. Schwartz, P.O. Etringer, “Systolic time intervals as measures of the contractile state of the left ventricular myocardium in man”, Circulation, vol. 46, no. 3, 1972, pp. 559-571.
- [2] J. T. Cacioppo, G. G. Berntson, P. F. Binkley, K. S. Quigley, B. N. Uchino, A. Fieldstone, “Autonomic cardiac control. II. Noninvasive indices and basal response as revealed by autonomic blockades”, Psychophysiology, vol. 31, no. 6, 1994, pp. 586-598.
- [3] H. Schächinger, M. Weinbacher, A. Kiss, R. Ritz, W. Langewitz, “Cardiovascular indices of peripheral and central sympathetic activation”, Psychosom Med., vol. 63, no. 5, 2001. pp. 788-96.
- [4] K. A. Brownley, A. L. Hinderliter, S. G. West, S. S. Girdler, A. Sherwood, K. C. Light, “Sympathoadrenergic mechanisms in reduced hemodynamic stress responses after exercise”, Med Sci Sports Exerc., vol. 35, no. 6, 2003, pp. 978-986.
- [5] A. D. Goedhart, G. Willemsen, J. H. Houtveen, D. I. Boomsma, E.J. De Geus, “Comparing low frequency heart rate variability and pre-ejection period: two sides of a different coin”, Psychophysiology, vol. 45, no. 6, 2008, pp.1086-1090.
- [6] J. H. Meijer, S. Boesveldt, E. Elbertse, H.W. Berendse, “Method to measure autonomic control of cardiac function using time interval parameters from impedance cardiography”, Physiol Meas., vol. 29, no. 6, 2008, pp. S383-S391.
- [7] C. M. Licht, S. A. Vreeburg, A. K. van Reedt Dortland, E. J. Giltay, W. J. Hoogendijk, R. H. DeRijk, N. Vogelzangs, F. G. Zitman, E. J. de Geus, B. W. Penninx, “Increased sympathetic and decreased parasympathetic activity rather than changes in hypothalamic-pituitary-adrenal axis activity is associated with metabolic abnormalities”, J. Clin. Endocrinol. Metab., vol. 95, no. 5, 2010, pp. 2458-2466.
- [8] J. B. Hinnant, L. Elmore-Staton, M. El-Sheikh, “Developmental trajectories of respiratory sinus arrhythmia and pre-ejection period in middle childhood”, Dev Psychobiol., vol. 53, no. 1, 2011, pp. 59-68.
- [9] M. F. O’Rourke, T. Yaginuma, A. P. Avolio “Physiological and pathophysiological implication of ventricular/ vascular coupling”, Annals of Biomedical Engineering, vol. 12, 1984, pp. 119-134.
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Bibliografia
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bwmeta1.element.baztech-article-BUJ8-0016-0014