68Ge/68Ga radioisotope generator as a source of radiotracers for water flow investigations

• Autorzy: Palige J. , Majkowska A. , Herdzik I. , Ptaszek S.
• Języki publikacji: EN

Abstrakty

EN

Radiotracer experiments on the model of rectangular settler with a volume of 3 m3, with a consecutive application as a tracer of the aqueous phase fluoresceine (representative tracer of water), eluate from a 68Ge/68Ga radioisotope generator (0.1 N HCl solution) and chelates after Ga ions complexation with 1,4,7-triazacyclononane-1,4,7-triacetic acid (NOTA) and 1,4,7,10-tetrazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) were carried out. The obtained residence time distribution (RTD) functions indicate that only the complex compounds of gallium are stable in the water phase and are not adsorb on the vessel walls, so they can be recommended as tracers of the water phase.

Słowa kluczowe

EN

Ga-68; generator; residence time distribution (RTD)

• Wydawca: Institute of Nuclear Chemistry and Technology
• Czasopismo: Nukleonika
• Rocznik: 2011
• Tom: Vol. 56, No. 1
• Strony: 77--80
• Opis fizyczny: Bibliogr. 6 poz., rys.

Twórcy

autor

Palige J.

autor

Majkowska A.

autor

Herdzik I.

autor

Ptaszek S.

• Institute of Nuclear Chemistry and Technology, 16 Dorodna Str., 03-195 Warsaw, Poland, Tel.: [phone], Fax: [phone],

Bibliografia

• 1. Borroto JI, Dominguez J, Griffith J, Fick M, Leclerc JP (2003) Technetium-99m as a tracer for liquid RTD measurement in opaque anaerobic digester. Chem Eng Process 42;11:857–865
• 2. IAEA (2008) Radiotracer residence time distribution method for industrial and environmental application. Training Course Series no. 31. International Atomic Energy Agency, Vienna
• 3. Miernicka M, Budzisz E (2007) Gallium compounds – chance for medicine of XXI century. Wiadomości Chemiczne 61;11/12:937–962 (in Polish)
• 4. Palige J, Owczarczyk A, Ptaszek S (2004) Applications of tracers and CFD methods for investigations of wastewater treatment installations. In: Proc of the Int Conf TRACER 3, 22–24 June 2004, Ciechocinek, Poland, pp 129–137
• 5. Prata MIM, Santos AC, Geraldes CFGC, de Lima JJP (2000) Structural and in vivo studies of metal chelates of Ga(III) relevant to biomedical imaging. J Inorg Biochem 79:359–363
• 6. Zhernosekov KP, Filosofov DV, Baum RP et al. (2007) Processing of generator – produced 68Ga for medical application. J Nucl Med 48;10:1741–1748