Synthesis of 3,3- and 4,4-Alkyl-phenyl-substituted Pyrrolidin-2-one Derivatives

• Autorzy: Kulig K. , Ignasik M. , Malawska B.
• Języki publikacji: EN

Abstrakty

EN

Syn the ses of 3,3- and 4,4-alkyl-phenyl-substi tuted pyrrolidin-2-one derivatives are described. The final compounds were obtained by the reductive cyclization of relevant cyanoalkanoate esters using NaBH4 and CoCl2×6H2O. The obtained pyrrolidin-2-one derivatives are pharmacophoric fragments for the syn thesis of various biologically active compounds.

Słowa kluczowe

EN

3,3-alkyl-phenyl-pyrrolidin-2-one derivatives; 4,4-alkyl-phenyl-pyrroli-din-2-one derivatives; reductive cyclization

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2009
• Tom: Vol. 83, nr 9
• Strony: 1629--1636
• Opis fizyczny: Bibliogr. 16 poz., rys.

Twórcy

autor

Kulig K.

autor

Ignasik M.

autor

Malawska B.

• Department of Physicochemical Drug Analysis, Chair of Pharmaceutical Chemistry, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland Phone: [phone],

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