Studies on the Deamination of the Ethyl Ester of 5-Amino-3-methylisoxazole-4-carboxylic Acid

• Autorzy: Ryng S. , Szostak M.
• Języki publikacji: EN

Abstrakty

EN

The unusual behavior of the ethyl ester of 5-amino-3-methylisoxazole-4-carboxylic acid (1) during deamination is described. Possible explanations for the anomalies of the diazotization reaction are proposed. Deamination methods leading to ethyl ester of 3-methylisoxazole-4-carboxylic acid (5) are presented. 5 will serve as a lead compound for a new series of immunomodulatory agents.

Słowa kluczowe

EN

isoxazoles; diazotization; deamination; hydrogen bonding; immunological activity

• Wydawca: Polskie Towarzystwo Chemiczne
• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2009
• Tom: Vol. 83, nr 5
• Strony: 887--893
• Opis fizyczny: Bibliogr. 22 poz., rys.

Twórcy

autor

Ryng S.

autor

Szostak M.

• Department of Organic Chemistry, Faculty of Pharmacy, University of Medicine, Grodzka 9, 50-137 Wroclaw, Poland,

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