Tytuł artykułu
Treść / Zawartość
Pełne teksty:
Identyfikatory
Warianty tytułu
Języki publikacji
Abstrakty
Preliminary design of a spherical brain PET (SBPET) using liquid xenon (LXe) as detector is considered in this research work. The major advantage of a spherical design is the large solid angle of acceptance which improves the sensitivity and increases signal-to-noise ratio (SNR) of the image. The use of a liquid active medium enabled us to design a spherical detector. LXe, due to the intrinsic physical properties, is an excellent liquid medium for accurate tracking of gamma rays in the relevant energy range. The performance of SBPET was evaluated by Monte Carlo simulation tools (GATE) and compared to ECAT HRRT. The numerical results showed the SBPET has a sensitivity of 1.14% and spatial resolution of ~2.7 mm FWHM which is superior to ECAT HRRT especially at high-count rates.
Czasopismo
Rocznik
Tom
Strony
33--38
Opis fizyczny
Bibliogr. 39 poz., rys.
Twórcy
autor
autor
autor
autor
autor
- Physics Department, University of Isfahan, Hezar jerib Ave., P. O. Box 81745-319, Isfahan, Iran, Tel.: +98 21 2212 7215, Fax: +98 21 8861 3937, mortazavi@alzahra.ac.ir
Bibliografia
- 1. Balldini C, Bemporad FC, Doke T (2004) Liquid Xe scintillation calorimetry and Xe optical properties. arXiv:physics/0401072
- 2. Bataille F, Comtat C, Jan S, Trebossen R (2004) Monte Carlo simulation for the ECAT HRRT using GATE. Nuclear Science Symp Conf Record IEEE 4:2570–2574
- 3. Buvate I, Castiglioni I (2002) Monte Carlo simulation in SPET and PET. J Nucl Med 46:48–61
- 4. Chepel V, Lopes MI, Kurchenkov A, Ferreira Marques R, Policarpo AJPL (1997) Performance study of liquid xenon detector for PET. Nucl Instrum Methods A 392:427–432
- 5. Chepel V, Lopes M, Solvov V, Ferreira Marques R, Policarpo AJPL (2001) Development of liquid xenon detector for medical imaging. World Sci (28-11-02) 11;58:1–13
- 6. Collot J, Jan S (2001) A liquid xenon PET camera for neuro-science. In: Proc of the 9th Int Conf Calorimetry in High Energy Physics. arXiv.org/pdf/physics/0211117
- 7. Cussonneau JP, Carlier T, Couturier O et al. (2005) Simulation and evaluation of a new PET system based on Liquid Xenon as detection medium. ICDL IEEE Int Conf, pp 357–360
- 8. DeGrado TR, Turkington TG, Williams JJ, Stearn CW,Hoffman JM, Coleman RE (1994) Performance characteristics of a whole-body PET scanner. J Nucl Med 35:1398–1406
- 9. Del Guerra A, Bisogni MG, Damiani C, Di Domenico G, Marchesini R, Zavattini G (2000) New developments in photo detection for medicine. Nucl Instrum Methods A 442:18–25
- 10. Derenzo SE, Weber MJ, Bourret-Courchesne E, Klintenberg MK (2003) The quest for the ideal inorganic scintillator. Nucl Instrum Methods A 505:111–117
- 11. Doke T, Kikuchi J, Nishikido F (2006) Time of flight positron emission tomograghy using liquid xenon scintillation. Nucl Instrum Methods A 569:863–871
- 12. Eijk CWE van (2002) Inorganic scintillators in medical imaging. Phys Med Biol 47:R85–R106
- 13. Gallin-Martel ML, Martin P, Mayet F et al. (2006) Experimental study of a liquid xenon PET prototype module. Nucl Instrum Methods A 563:225–228
- 14. Herzog H, Tellmann L, Hocke C et al. (2004) NEMA NU2-2001 guided performance evaluation of four Siemens ECAT PET scanners. IEEE Trans Nucl Sci 51;5:2662–2669
- 15. Hoffman EJ, Phelps ME, Huang SC (1983) Performance evaluation of a positron tomograph designed for brain imaging. J Nucl Med 24:245–257
- 16. http://www.oken.co.jp/web_oken/Mgf2_jp.htm
- 17. Humm JL, Rosenfeld A, Del Guerra A (2003) From PET detector to PET scanners. Eur J Nucl Med Mol Imag 30:11:1574–1597
- 18. Jan S, Collet J, Tournefier E (2000) A liquid xenon PET camera – simulation and position sensitive PMT test. Nuclear Science Symp Conf Record IEEE, pp 23–26
- 19. Jan S, Santin G, Strul D et al. (2004) Gate: a simulation toolkit for PET and SPECT. arXiv:physics/0408109
- 20. Karimian A, Thompson CJ, Sarkar S et al. (2004) A dedicated PET system for breast imaging (CYBPET). Nuclear Science and Medical Imaging Symp Conf Record IEEE 4:2339–2341
- 21. Karimian A, Thompson S, Sarkar S, Raisali G, Pani R (2005) CYBPET: A cylindrical PET system for breast imaging. Nucl Instrum Methods Phys Res A 545:427–435
- 22. Lartizien C, Comtat C, Kinahan PE, Ferreira N, Bendriem B, Trebossen R (2002) Optimization of injected dose based on noise equivalent count rates for 2- and 3-dimensional whole-body PET. J Nucl Med 43:1268–1278
- 23. Mortazavi N, Karimian A, Mostajaboddavati M (2006) Design of new dedicated brain PET system by Monte Carlo method. World J Nucl Med 5:S215, 3653
- 24. Mortazavi Moghaddam N (2007) Design of a new dedicated brain PET system by GATE, EANM 2007, Kopinhag, Denmark: S-158, 179
- 25. Moses WW, Virador PRG, Derenzo SE, Huesman RH, Budinger TF (1997) Design of a high resolution, highsensitivity PET camera for human brains and small animals. IEEE Trans Nucl Sci 44:1487–1491
- 26. NEMA (2000) Standards Publication NU 2-2000. National Electrical Manufactures Association, Washington, DC
- 27. Nishikido F, Doke T, Kikuchi J, Mori T (2004) Performance of a prototype of liquid xenon scintillation detector system for positron emission tomography. Japanese J Appl Phys 43;2:779–784
- 28. Nutt R (2002) The history of positron emission tomography. Mol Imag Biol 4;1:11–26
- 29. Saha GB (2004) Basics of PET imaging. Springer, New York
- 30. Santin G, Strul DE, Lazaro D, Simon L, Morel C (2002) Gate: A Geant4 – based simulation platform for PET and SPECT integrating movement and time management. Nuclear Science Symp Conf Record IEEE 2:1325–1329
- 31. Schmidtlein CR, Kirov AS, Nehmeh SA, Erdi YE (2006) Validation of gate Monte Carlo simulations of the GE advance/discovery LS PET scanner. Med Phys 33;1:198–208
- 32. Seguinot J, Braem A, Chesi E et al. (2005) Novel geometrical concept of high performance brain PET scanner: principle, design and performance estimates. Pre-print CERN PH EP/2004 050
- 33. Sossi V (2003) Positron emission tomography (PET) advances in neurological applications. Nucl Instrum Methods A 510:107–115
- 34. Thers D (2005) PET, imaging technologies and electronics. In: XeSAT Proceedings, Waseda University, Tokyo, Japan, pp 84–89
- 35. Thompson CJ, Yamamoto YL, Meyer E (1979) Positome II: A high efficiency positron imaging device for dynamic brain studies. IEEE Trans Nucl Sci 26;1:583–589
- 36. Townsend DW, Defrise M (1993) Image reconstruction methods in positron tomography. Academic Training Program of CERN, Report No 93-02, CERN, Division de Medicine Nuclear, Hospital Cantonal Universities de Geneve, Geneva, Switzerland
- 37. Wienhard K, Schmand M, Casey ME et al. (2003) The ECAT HRRT: performance and first clinical application of the new high resolution research tomograph. IEEE Trans Nucl Sci 49:104–110
- 38. Zaidi H, Montandon M (2005) Atlas guided non-uniform attenuation in cerebral 3D PET imaging. Neuro Image 25:278–286
- 39. Zaidi H, Montandon ML (2006) The new challenges of brain technology. Curr Med Imag Rev 2;15:3–13
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BUJ6-0025-0059