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Języki publikacji
Abstrakty
Synthesis of 6-aminoindan-1-one and 7-amino-5,6-dimethoxyindan-1-one by nitration of corresponding indanones, followed by selective palladium catalyzed reduction under mild conditions has been described. Reactions of the amines with oxirane leading to N,N-bis-(beta-hydroxyethyl) derivatives were performed. The study of reductive amination of 6-nitroindan-1-one and 5,6-dimethoxy-7-nitroindan-1-one via azines to the corresponding amines as well as synthesis of N,N-bis-(beta-hydroxyethyl) derivatives of the amines was also described.
Słowa kluczowe
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Czasopismo
Rocznik
Tom
Strony
2133--2140
Opis fizyczny
Bibliogr. 13 poz., rys.
Twórcy
autor
autor
- Institute of Organic Technology, Technical University of Szczecin, Al. Piastów 42, 71-065 Szczecin, Poland, halina.kwiecien@ps.pl
Bibliografia
- 1. Hasbun J.A., Barker K.K. and Mertes M.P., J. Med. Chem., 16, 847 (1973).
- 2. Li C.-S., Black C., Chan C.-C, Ford-Hutchinson A. W., Gauthier J.-Y., Gordon R., Guay D., Kargman S.,Lau C.K., Mancini J., Ouimet N., Roy R, Vickers R, Wong E., Young R.N., Zamboni R. and Prasit R, J. Med. Chem., 38, 4897 (1995).
- 3. Guay D.R.R, Am. J. Geriatr. Pharmacother., 4(4), 330 (2006).
- 4. Akao Y, Maruyama W., Yi H., Shamoto-Nagai M., Youdim M.B.H. and Naoi M., Neurosci. Lett., 326,105 (2002).
- 5. Youdim M.B.H., Amit T., Falach-Vogev M., Am O.B., Maruyama W. and Naoi M., Biochem. Pharmacol., 66, 1635 (2003).
- 6. Am O.B., Amit T. and Youdim M.B.H., Neurosci. Lett., 355, 169 (2004).
- 7. Binda C., Hubalek R, Li M., Herzig Y, Sterling J., Edmondson D.E. and Mattevi A., J. Med. Chem., 48(26), 8148 (2005).
- 8. Leoni L.M., Hamel E., Genini D., Shih H., Carrera C.J., Cottam H.B. and Carson D.A., J. Natl. Cancer Inst., 92(3), 217 (2000).
- 9. Shih H., Deng L., Carrera C.J., Adachi S., Cottam H.B. and Carson D.A., Bioorg. Med. Chem. Lett., 10,487 (2000).
- 10. Kwiecień H. and Szychowska M., Synth. Commun., 37, 3599 (2007).
- 11. Ingold C.K. and Piggott H.A., J. Chem. Soc., 123, 1475 (1923).
- 12. Wan R, Davis M.J. and Teo M.A., J. Org. Chem., 54(6), 1354 (1989).
- 13. Musso D.L., Cochran F.R., Kelley J.L., McLean E.W., Selph J.L., Rigdon G.C., Orr G.R, Davis R.G.,Cooper B.R., Styles V.L., Thompson J.B. and Hall W.R., J. Med. Chem., 43(3), 399 (2003).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BUJ6-0025-0011