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Evaluation of set-up verification with the analysis of systematic and random errors in radiotherapy - a study of the Great Poland Cancer Centre

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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The aim of this study was the examination of influence of location tumors and methods of immobilizing on values of geometrical errors during treatment, and the analysis of set-up errors in reference to the method of irradiation in three groups of patients before and after corrections. This study included three groups of patients with prostate cancer (59 patients, 277 portal images), head and neck (60 patients, 285 portal images) and brain tumor (45 patients, 175 portal images). Ratios of IMRT vs. 3D-CRT were respectively: in I group 76% vs. 24%, in II group 95% vs. 5% and III group 83% vs. 17%. Set-up errors were compared in reference to the technique of irradiation and stage of treatment. The displacements were significantly higher in the first group compared with head, neck and brain tumors; 5.66, 4.05, 3.93 mm, respectively. The values of the vector lengths were significantly dependent on the type of irradiation technique (3D-CRT vs. IMRT) only in the first group (p < 0.001). The average of vector length in I, II and III group were significantly reduced from; 5.67, 4.02, 3.91 mm to 5.13, 3.63, 3.57 mm after correction, respectively. The Spearman test is indicating a low negative correlation between set-up errors and the following fractions. The applied methods of patients positioning with prostate cancer produce a worse repeatability than the ones used for patients with head, neck and brain cancers. Portal verification reduces values of set-up errors. Significant differences in the magnitude of displacements before and after correction were observed. No significant differences between value of displacement and number of fraction were revealed.
Czasopismo
Rocznik
Strony
167--171
Opis fizyczny
Bibliogr. 13 poz., rys.
Twórcy
autor
autor
autor
  • Department of Medical Physics, Great Poland Cancer Centre, 15 Garbary Str., 61-866 Poznań, Poland, Tel.: +48 61 854 05 53, Fax: +48 61 854 05 50, szczureklukasz@gmail.com
Bibliografia
  • 1. Alasti H, Petric PN, Catton C et al. (2001) Portal imaging for evaluation of daily on-line setup errors and off-line organ motion during conformal irradiation of carcinoma of the prostate. Int J Radiat Oncol Biol Phys 49:869–884
  • 2. Boehmer D, Bohsung J, Eichwurzel I et al. (2004)Clinical and physical quality assurance for intensity modulated radiotherapy of prostate cancer. Radiother Oncol 71:319–325
  • 3. Coen W, Hurkmans, Remeijer P et al. (2001) Set-up verification using portal imaging; review of current clinical practice. Radiother Oncol 58:105–120
  • 4. Dawson LA, Litzenberg DW, Brock KK et al. (2000) A comparison of ventilatory prostate movement in four treatment positions. Int J Radiat Oncol Biol Phys 48:319–323
  • 5. Di Yan, Wong J, Michalski J et al. (1997) Adaptive modification of treatment planning to minimize the deleterious effects of treatment setup errors. Int J Radiat Oncol Biol Phys 38:197–206
  • 6. Hashimoto S, Shirato H, Nishioka T et al. (2001) Remote verification in radiotherapy using digitally reconstructed radiography (DRR) and portal images: a pilot study. Int J Radiat Oncol Biol Phys 50:579–585
  • 7. Malicki J, Milecki P, Nawrocki S et al. (2001) Evaluation of an electronic portal imaging device (Target view, GE) as a quality assurance tool. Reports of Practical Oncology and Radiotherapy 6;4:169–172
  • 8. Manning MA, Wu Q, Cardinale RM et al. (2001) The effect of setup uncertainty on normal tissue sparing with IMRT for head-and-neck cancer. Int J Radiat Oncol Biol Phys 51:1400–1409
  • 9. Remeuer P, Geerlof E, Ploger L et al. (2000) 3-D portal image analysis in clinical practice: an evaluation of 2-D and 3-D analysis techniques as applied to 30 prostate cancer patients. Int J Radiat Oncol Biol Phys 46:1281–1290
  • 10. Samuelsson A, Mercke C, Johansson K et al. (2003) Systematic set-up errors for IMRT in the head and neck region: effect on dose distribution. Radiother Oncol 66:303–311
  • 11. Smitsmans M, Wolthaus J, Artigan X et al. (2001) Automatic localization of the prostate for on-line or off-line image-guided radiotherapy. Int J Radiat Oncol Biol Phys 60:623–635
  • 12. Song PY, Washington M, Vaida F et al. (1996) A comparison of four patient immobilization devices in the treatment of prostate cancer patients with three dimensional conformal therapy. Int J Radiat Oncol Biol Phys 34:213–219
  • 13. Suzuki M, Nishimura Y, Nakamatsu K et al. (2006) Analysis of interfractional set-up errors and intrafractional organ motions during IMRT for head and neck tumors to define an appropriate planning target volume (PTV) – and planning organs at risk volume (PRV) – margins. Radiother Oncol 78:283–290
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BUJ6-0023-0038
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